ID A0A2H0ZR57_CANAR Unreviewed; 121 AA.
AC A0A2H0ZR57; A0A5Q7YB66;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=6-O-methylguanine-DNA methyltransferase {ECO:0000256|ARBA:ARBA00030795};
DE AltName: Full=DNA repair MTase {ECO:0000256|ARBA:ARBA00033095};
DE AltName: Full=O-6-methylguanine-DNA-alkyltransferase {ECO:0000256|ARBA:ARBA00031621};
GN ORFNames=B9J08_002752 {ECO:0000313|EMBL:PIS51178.1};
OS Candida auris (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Metschnikowiaceae; Metschnikowiaceae incertae sedis;
OC Candida/Metschnikowiaceae.
OX NCBI_TaxID=498019 {ECO:0000313|EMBL:PIS51178.1, ECO:0000313|Proteomes:UP000230249};
RN [1] {ECO:0000313|EMBL:PIS51178.1, ECO:0000313|Proteomes:UP000230249}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B8441 {ECO:0000313|EMBL:PIS51178.1,
RC ECO:0000313|Proteomes:UP000230249};
RX PubMed=27988485; DOI=.1093/cid/ciw691;
RA Lockhart S.R., Etienne K.A., Vallabhaneni S., Farooqi J., Chowdhary A.,
RA Govender N.P., Colombo A.L., Calvo B., Cuomo C.A., Desjardins C.A.,
RA Berkow E.L., Castanheira M., Magobo R.E., Jabeen K., Asghar R.J.,
RA Meis J.F., Jackson B., Chiller T., Litvintseva A.P.;
RT "Simultaneous emergence of multidrug-resistant Candida auris on 3
RT continents confirmed by whole-genome sequencing and epidemiological
RT analyses.";
RL Clin. Infect. Dis. 64:134-140(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PIS51178.1}.
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DR EMBL; PEKT02000007; PIS51178.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2H0ZR57; -.
DR EnsemblFungi; B9J08_002752-t37_1; B9J08_002752-t37_1-p1; B9J08_002752.
DR VEuPathDB; FungiDB:B9J08_002752; -.
DR VEuPathDB; FungiDB:CJI96_0000594; -.
DR VEuPathDB; FungiDB:CJI97_002806; -.
DR VEuPathDB; FungiDB:CJJ07_002531; -.
DR VEuPathDB; FungiDB:CJJ09_001342; -.
DR VEuPathDB; FungiDB:QG37_07028; -.
DR OMA; DEAEWWF; -.
DR OrthoDB; 2787022at2759; -.
DR Proteomes; UP000230249; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR CDD; cd06445; ATase; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR014048; MethylDNA_cys_MeTrfase_DNA-bd.
DR InterPro; IPR036217; MethylDNA_cys_MeTrfase_DNAb.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR42942; 6-O-METHYLGUANINE DNA METHYLTRANSFERASE; 1.
DR PANTHER; PTHR42942:SF1; ALKYLTRANSFERASE-LIKE PROTEIN 1; 1.
DR Pfam; PF01035; DNA_binding_1; 1.
DR SUPFAM; SSF46767; Methylated DNA-protein cysteine methyltransferase, C-terminal domain; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000230249}.
FT DOMAIN 10..100
FT /note="Methylated-DNA-[protein]-cysteine S-
FT methyltransferase DNA binding"
FT /evidence="ECO:0000259|Pfam:PF01035"
SQ SEQUENCE 121 AA; 13873 MW; 6A86C38602A925F8 CRC64;
MNLDDEKKAF HYAVYDTVSR IPHGNVTTYG HIAYLIGRPQ NSRQVGSSLK HLRYIRERLN
QEGAGLGEVP WWRVVNSAGI ISPRNFGEFE QATLLRGEGV VVSERHKMDL EQYGWFPDDV
E
//
