ID A0A2H0ZW61_CANAR Unreviewed; 987 AA.
AC A0A2H0ZW61;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 22-FEB-2023, entry version 17.
DE RecName: Full=Importin N-terminal domain-containing protein {ECO:0000259|PROSITE:PS50166};
GN ORFNames=B9J08_001992 {ECO:0000313|EMBL:PIS54845.1};
OS Candida auris (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Metschnikowiaceae; Metschnikowiaceae incertae sedis;
OC Candida/Metschnikowiaceae.
OX NCBI_TaxID=498019 {ECO:0000313|EMBL:PIS54845.1, ECO:0000313|Proteomes:UP000230249};
RN [1] {ECO:0000313|EMBL:PIS54845.1, ECO:0000313|Proteomes:UP000230249}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B8441 {ECO:0000313|EMBL:PIS54845.1,
RC ECO:0000313|Proteomes:UP000230249};
RX PubMed=27988485; DOI=.1093/cid/ciw691;
RA Lockhart S.R., Etienne K.A., Vallabhaneni S., Farooqi J., Chowdhary A.,
RA Govender N.P., Colombo A.L., Calvo B., Cuomo C.A., Desjardins C.A.,
RA Berkow E.L., Castanheira M., Magobo R.E., Jabeen K., Asghar R.J.,
RA Meis J.F., Jackson B., Chiller T., Litvintseva A.P.;
RT "Simultaneous emergence of multidrug-resistant Candida auris on 3
RT continents confirmed by whole-genome sequencing and epidemiological
RT analyses.";
RL Clin. Infect. Dis. 64:134-140(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PIS54845.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; PEKT02000005; PIS54845.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2H0ZW61; -.
DR STRING; 498019.A0A2H0ZW61; -.
DR EnsemblFungi; B9J08_001992-t37_1; B9J08_001992-t37_1-p1; B9J08_001992.
DR VEuPathDB; FungiDB:B9J08_001992; -.
DR VEuPathDB; FungiDB:CJI96_0002667; -.
DR VEuPathDB; FungiDB:CJI97_002183; -.
DR VEuPathDB; FungiDB:CJJ07_000402; -.
DR VEuPathDB; FungiDB:CJJ09_003079; -.
DR VEuPathDB; FungiDB:QG37_08174; -.
DR OMA; SFHYVFH; -.
DR OrthoDB; 6327at2759; -.
DR Proteomes; UP000230249; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0051170; P:import into nucleus; IEA:UniProt.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR001494; Importin-beta_N.
DR PANTHER; PTHR10997:SF7; IMPORTIN-11; 1.
DR PANTHER; PTHR10997; IMPORTIN-7, 8, 11; 1.
DR Pfam; PF03810; IBN_N; 1.
DR SMART; SM00913; IBN_N; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000230249}.
FT DOMAIN 27..99
FT /note="Importin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50166"
SQ SEQUENCE 987 AA; 113694 MW; A2EB8A14627C22CA CRC64;
MAVETDELLK VLYIVDGAER SSLQHEAEAQ LKKWESEPGY HYALQNIYLN TELPMHVRWL
AVICFKNGVE KHWRPSRLNA IGKEEKTKIK ERLFNLISEN NSQLTIQNAH SIARIVRFDF
PSEWPTLFDD LSKTLEDYVF VQGNLVATNN LLVVLNQIIK AVSMVRIGRS RHAMQSKAPI
IVPILIKSYC KFFQMWTSSL DLTIMEVCYL CLKNLRRIIP EGFEQPHTNQ DITDFLKLSV
SHLQGLVTEH EKYSSDLLER YVKSYSKLYV NLINSNPTSF VLIPCSSEII TTFLSLLKNR
AEDVYKSSED NDFWETLALK GFLILKKMVA YVYKQGAVTL KQRNDKEDVG NAINKLKTQL
FTPEVIFSLC DLIINWYLKL KPSDLESWLL EPEEWVNEEL SSSWEYQVRP CAENFYQDLI
KYFKDELCDF ILNKISNGLT QNESVSDILT KDSILCTFQL SADSIANRVN FDQLLTQVFI
PEGLKNDLVE NKIIKRRVCL IISTWVPVNC SRESRVNIYK LLINFLQPVN KFNDKVVRLT
SIQTLRTIIN DWDFNKQDFQ PFLKEYVSLS LNMLEDMSFT ESKLYILDTL SVLIERCNPL
IDETTLMAIL QIVPSYWEIS KKQEEAILQS SLLRVLKQLV IALNQNSSHT HFITLPLIKA
CCTQSSEHYS LLSEDGFDLW LAVVQYYPID MTPNESLVEL FSLLHPALMD ATEILPTILS
IARSYTLLIP KLFETDAGLE AFRVLSGYLP KMRDDAFDIF ITMADILLLQ ESEDDQLINN
LINSGLLNAM ASYVLDENHS VVLANKILLV LSRLATSSAE AFLNVLQHLQ IDSAKFIDVW
MNYYKNNGNP RNKKVNLLAL ISLAVYCVSK NLHGVPQRFG ELERNCFLFL EEVNEDESGN
CQAYAGDYIY SDVDNYAYLD PDIAPHGEKL RYSKLLEEKD PILKVKMQQY LRDALIKLRG
ELNESDFATL MSLNDQYTSE KLQQLLA
//
