ID A0A2H0ZYW6_CANAR Unreviewed; 459 AA.
AC A0A2H0ZYW6;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Sec20-domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=B9J08_001634 {ECO:0000313|EMBL:PIS55532.1}, CA7LBN_001560
GN {ECO:0000313|EMBL:QWW22813.1};
OS Candida auris (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Metschnikowiaceae; Metschnikowiaceae incertae sedis;
OC Candida/Metschnikowiaceae.
OX NCBI_TaxID=498019 {ECO:0000313|EMBL:PIS55532.1, ECO:0000313|Proteomes:UP000230249};
RN [1] {ECO:0000313|EMBL:PIS55532.1, ECO:0000313|Proteomes:UP000230249}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B8441 {ECO:0000313|EMBL:PIS55532.1,
RC ECO:0000313|Proteomes:UP000230249};
RX PubMed=27988485; DOI=.1093/cid/ciw691;
RA Lockhart S.R., Etienne K.A., Vallabhaneni S., Farooqi J., Chowdhary A.,
RA Govender N.P., Colombo A.L., Calvo B., Cuomo C.A., Desjardins C.A.,
RA Berkow E.L., Castanheira M., Magobo R.E., Jabeen K., Asghar R.J.,
RA Meis J.F., Jackson B., Chiller T., Litvintseva A.P.;
RT "Simultaneous emergence of multidrug-resistant Candida auris on 3
RT continents confirmed by whole-genome sequencing and epidemiological
RT analyses.";
RL Clin. Infect. Dis. 64:134-140(2017).
RN [2] {ECO:0000313|EMBL:PIS55532.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=B8441 {ECO:0000313|EMBL:PIS55532.1};
RA Munoz J.F., Gade L.G., Chow N.A., Litvintseva A.P., Loparev V.N.,
RA Cuomo C.A.;
RT "Candida auris genome assembly and annotation.";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:QWW22813.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CA7LBN {ECO:0000313|EMBL:QWW22813.1};
RA Finianos M.;
RT "Candida auris outbreak in lebanese hospital.";
RL Submitted (JUN-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004163}; Single-pass type IV membrane protein
CC {ECO:0000256|ARBA:ARBA00004163}. Membrane
CC {ECO:0000256|ARBA:ARBA00004211}; Single-pass type IV membrane protein
CC {ECO:0000256|ARBA:ARBA00004211}.
CC -!- SIMILARITY: Belongs to the SEC20 family.
CC {ECO:0000256|ARBA:ARBA00037934}.
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DR EMBL; PEKT02000004; PIS55532.1; -; Genomic_DNA.
DR EMBL; CP076749; QWW22813.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2H0ZYW6; -.
DR STRING; 498019.A0A2H0ZYW6; -.
DR EnsemblFungi; B9J08_001634-t37_1; B9J08_001634-t37_1-p1; B9J08_001634.
DR VEuPathDB; FungiDB:B9J08_001634; -.
DR VEuPathDB; FungiDB:CJI96_0000099; -.
DR VEuPathDB; FungiDB:CJI97_001676; -.
DR VEuPathDB; FungiDB:CJJ07_000069; -.
DR VEuPathDB; FungiDB:CJJ09_001845; -.
DR VEuPathDB; FungiDB:QG37_05323; -.
DR OMA; WSFFKIF; -.
DR Proteomes; UP000230249; Unassembled WGS sequence.
DR Proteomes; UP000825438; Chromosome I.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005484; F:SNAP receptor activity; IEA:InterPro.
DR GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; IEA:InterPro.
DR InterPro; IPR005606; Sec20.
DR PANTHER; PTHR12825; BNIP1-RELATED; 1.
DR PANTHER; PTHR12825:SF0; VESICLE TRANSPORT PROTEIN SEC20; 1.
DR Pfam; PF03908; Sec20; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW ER-Golgi transport {ECO:0000256|ARBA:ARBA00022892};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000230249};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 232..252
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 341..372
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 459 AA; 51816 MW; C8AACF0B8BED1592 CRC64;
MSNTEIEAQT EALTRLKYSV FENIEEIRSL SAEDDESTSI ESKKETLTKQ AHSSISQMSD
LLSVLELLIL QCAPRSAEEN LLWEMLSIHK LTVQHLKDKL KDSQIAAYEQ QSKQVHAQIL
EEYVNKWRAE EGDTRDQLFA GRSAQPTGEK EKPIEEQVLN KNESITNNLK LTHQLMQMSV
AQTELNIDTI GQQTKDLSTL NDKLVDLESL LNKSRQIVKF IEKQDKHDKR RIYLSIGFLL
TCFAWVIWHR ILKLPTKILL WTLLRAFGVV TWATSKMNAS DTADSLSQSS GIAISSASHQ
ALSISSFIST VSSATETSTR SEALSIIEEI TSSIIEDIES ASRQTERFST EELSETSCGI
SEPRSEIDSE VKSVTTKEQY TTTPSTMIET RALQTNSSNH KSGDIELRDV SETTVKMSAL
EDNSVTTVDT SSIFTFRESD LRDLGFKKWN NEENFHDEL
//
