ID A0A2H1A5Q7_CANAR Unreviewed; 534 AA.
AC A0A2H1A5Q7;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=BRCT domain-containing protein {ECO:0000259|PROSITE:PS50172};
GN ORFNames=B9J08_000868 {ECO:0000313|EMBL:PIS58371.1}, CA7LBN_002420
GN {ECO:0000313|EMBL:QWW23619.1};
OS Candida auris (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Metschnikowiaceae; Metschnikowiaceae incertae sedis;
OC Candida/Metschnikowiaceae.
OX NCBI_TaxID=498019 {ECO:0000313|EMBL:PIS58371.1, ECO:0000313|Proteomes:UP000230249};
RN [1] {ECO:0000313|EMBL:PIS58371.1, ECO:0000313|Proteomes:UP000230249}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B8441 {ECO:0000313|EMBL:PIS58371.1,
RC ECO:0000313|Proteomes:UP000230249};
RX PubMed=27988485; DOI=.1093/cid/ciw691;
RA Lockhart S.R., Etienne K.A., Vallabhaneni S., Farooqi J., Chowdhary A.,
RA Govender N.P., Colombo A.L., Calvo B., Cuomo C.A., Desjardins C.A.,
RA Berkow E.L., Castanheira M., Magobo R.E., Jabeen K., Asghar R.J.,
RA Meis J.F., Jackson B., Chiller T., Litvintseva A.P.;
RT "Simultaneous emergence of multidrug-resistant Candida auris on 3
RT continents confirmed by whole-genome sequencing and epidemiological
RT analyses.";
RL Clin. Infect. Dis. 64:134-140(2017).
RN [2] {ECO:0000313|EMBL:PIS58371.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=B8441 {ECO:0000313|EMBL:PIS58371.1};
RA Munoz J.F., Gade L.G., Chow N.A., Litvintseva A.P., Loparev V.N.,
RA Cuomo C.A.;
RT "Candida auris genome assembly and annotation.";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:QWW23619.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CA7LBN {ECO:0000313|EMBL:QWW23619.1};
RA Finianos M.;
RT "Candida auris outbreak in lebanese hospital.";
RL Submitted (JUN-2021) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; PEKT02000002; PIS58371.1; -; Genomic_DNA.
DR EMBL; CP076750; QWW23619.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2H1A5Q7; -.
DR STRING; 498019.A0A2H1A5Q7; -.
DR EnsemblFungi; B9J08_000868-t37_1; B9J08_000868-t37_1-p1; B9J08_000868.
DR VEuPathDB; FungiDB:B9J08_000868; -.
DR VEuPathDB; FungiDB:CJI96_0003230; -.
DR VEuPathDB; FungiDB:CJI97_000886; -.
DR VEuPathDB; FungiDB:CJJ07_004456; -.
DR VEuPathDB; FungiDB:CJJ09_002829; -.
DR VEuPathDB; FungiDB:QG37_02809; -.
DR OMA; EFWDLQR; -.
DR OrthoDB; 69173at2759; -.
DR Proteomes; UP000230249; Unassembled WGS sequence.
DR Proteomes; UP000825438; Chromosome II.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd17742; BRCT_CHS5_like; 1.
DR CDD; cd13945; Chs5_N; 1.
DR Gene3D; 6.20.120.50; -; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR031673; Chs5_N.
DR InterPro; IPR031669; Fn3_2.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR47351; CHITIN BIOSYNTHESIS PROTEIN CHS5; 1.
DR PANTHER; PTHR47351:SF1; CHITIN BIOSYNTHESIS PROTEIN CHS5; 1.
DR Pfam; PF00533; BRCT; 1.
DR Pfam; PF16892; CHS5_N; 1.
DR Pfam; PF16893; fn3_2; 1.
DR SMART; SM00292; BRCT; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR PROSITE; PS50172; BRCT; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000230249}.
FT DOMAIN 164..259
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT REGION 276..534
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 292..306
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 307..324
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 326..340
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 341..383
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 403..449
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 464..485
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 486..507
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 534 AA; 58850 MW; 50EE28850EA24ECC CRC64;
MVEVSLTVGK LDASLALLLT KDHHLIEFPT ILLPNGVKAG SIVKIRCDRD LETELEEKKQ
FQAIQDEIIN TFGKNLPKAP QLRVKNVTQT SCVLEWDQLD LGTASLKNLV LFRDGKKLGA
IPQAMTNKTT KLSGLPIDKT FKFHLRLDTT AGVYKSEEVE VTTHKMTDLS GITVCLGDIT
PNDQFTVEDI QAALKNMGAH HPAQETVKVD TTHFITMREN KQNPEYVKAN DMNIPIIRPE
WLKACERERR IVGVRDFYVK DCSLPDILAR NYWKKDAPAK STEASKDTLE GPPVVQVTSP
SPETTSKQDL NEKDEGKDSG VPSSEAVEEA KSSENTSGEV SESSKKSEKE GEVKSDEKPD
ENATVDVTKN EDEVGRTDEL DNAQKASETS MSLREEESTK QAIAEPTEQV VTDSKEKTNT
NAVEGTPNAA SIETQQAETS AQPTAEELTE VDLNESHPES GVAESTDLPK KIEKEEIQEA
KEDDTIAEGV DGDEGDENDD DDENENANGK ETTDQPAGES KSKKKNKKKK KGKK
//
