ID A0A2H1A5U0_CANAR Unreviewed; 280 AA.
AC A0A2H1A5U0; A0A5Q7YIN2;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 08-NOV-2023, entry version 22.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:PIS58250.1};
GN ORFNames=B9J08_000741 {ECO:0000313|EMBL:PIS58250.1};
OS Candida auris (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Metschnikowiaceae; Metschnikowiaceae incertae sedis;
OC Candida/Metschnikowiaceae.
OX NCBI_TaxID=498019 {ECO:0000313|EMBL:PIS58250.1, ECO:0000313|Proteomes:UP000230249};
RN [1] {ECO:0000313|EMBL:PIS58250.1, ECO:0000313|Proteomes:UP000230249}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B8441 {ECO:0000313|EMBL:PIS58250.1,
RC ECO:0000313|Proteomes:UP000230249};
RX PubMed=27988485; DOI=.1093/cid/ciw691;
RA Lockhart S.R., Etienne K.A., Vallabhaneni S., Farooqi J., Chowdhary A.,
RA Govender N.P., Colombo A.L., Calvo B., Cuomo C.A., Desjardins C.A.,
RA Berkow E.L., Castanheira M., Magobo R.E., Jabeen K., Asghar R.J.,
RA Meis J.F., Jackson B., Chiller T., Litvintseva A.P.;
RT "Simultaneous emergence of multidrug-resistant Candida auris on 3
RT continents confirmed by whole-genome sequencing and epidemiological
RT analyses.";
RL Clin. Infect. Dis. 64:134-140(2017).
CC -!- PATHWAY: Protein modification; protein sumoylation.
CC {ECO:0000256|ARBA:ARBA00004718}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the NSE2 family.
CC {ECO:0000256|ARBA:ARBA00008212}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PIS58250.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; PEKT02000002; PIS58250.1; -; Genomic_DNA.
DR STRING; 498019.A0A2H1A5U0; -.
DR EnsemblFungi; B9J08_000741-t37_1; B9J08_000741-t37_1-p1; B9J08_000741.
DR VEuPathDB; FungiDB:B9J08_000741; -.
DR VEuPathDB; FungiDB:CJI96_0003358; -.
DR VEuPathDB; FungiDB:CJI97_000742; -.
DR VEuPathDB; FungiDB:CJJ07_000578; -.
DR VEuPathDB; FungiDB:CJJ09_002701; -.
DR VEuPathDB; FungiDB:QG37_01599; -.
DR OMA; NTHRELV; -.
DR UniPathway; UPA00886; -.
DR Proteomes; UP000230249; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0030915; C:Smc5-Smc6 complex; IEA:InterPro.
DR GO; GO:0019789; F:SUMO transferase activity; IEA:InterPro.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0000724; P:double-strand break repair via homologous recombination; IEA:InterPro.
DR GO; GO:0016925; P:protein sumoylation; IEA:UniProtKB-UniPathway.
DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR CDD; cd16651; SPL-RING_NSE2; 1.
DR Gene3D; 1.20.120.1010; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR026846; Nse2(Mms21).
DR InterPro; IPR003613; Ubox_domain.
DR InterPro; IPR004181; Znf_MIZ.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR21330:SF1; E3 SUMO-PROTEIN LIGASE NSE2; 1.
DR PANTHER; PTHR21330; UNCHARACTERIZED; 1.
DR Pfam; PF11789; zf-Nse; 1.
DR SMART; SM00504; Ubox; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS51044; ZF_SP_RING; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000230249};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
SQ SEQUENCE 280 AA; 31939 MW; FE41D143AECBD89A CRC64;
MSSTEAAATG LPNFKDFPSY IPVHADIKVN TDSGSLLLLR ELDEKLQKIK DDAESLIEYA
SERSHLVQND KFQIYCSNTL KSYEQIYSAK VKLQALQSAM KNTHRELVEG RRSTLTLTLS
NYDSCKELMK RNFADSFSEN LDELLLEKSG AHLEGLLHRD PAFSYIKNAL FVLQNPEDPL
QDEQVDEELA VEGGKISLKD PLSLNYYSDP VVSKKCMHVF EREHIVRQIR ATREKYACPV
TGCNAYLTES DLSPDKLMKL RVKVYMGRAN KREHESVVRI
//
