ID A0A2H1BSG8_FASHE Unreviewed; 217 AA.
AC A0A2H1BSG8;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Cathepsin B {ECO:0000313|EMBL:THD18397.1};
GN ORFNames=D915_011152 {ECO:0000313|EMBL:THD18397.1};
OS Fasciola hepatica (Liver fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Plagiorchiida; Echinostomata; Echinostomatoidea; Fasciolidae;
OC Fasciola.
OX NCBI_TaxID=6192 {ECO:0000313|EMBL:THD18397.1, ECO:0000313|Proteomes:UP000230066};
RN [1] {ECO:0000313|EMBL:THD18397.1, ECO:0000313|Proteomes:UP000230066}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Choi Y.-J., Martin J., Mitreva M.;
RT "Improved annotation for the trematode Fasciola hepatica.";
RL Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase C1 family.
CC {ECO:0000256|ARBA:ARBA00008455}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:THD18397.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JXXN02012900; THD18397.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2H1BSG8; -.
DR Proteomes; UP000230066; Unassembled WGS sequence.
DR GO; GO:0008234; F:cysteine-type peptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd02620; Peptidase_C1A_CathepsinB; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR013128; Peptidase_C1A.
DR InterPro; IPR000668; Peptidase_C1A_C.
DR PANTHER; PTHR12411:SF895; CATHEPSIN B; 1.
DR PANTHER; PTHR12411; CYSTEINE PROTEASE FAMILY C1-RELATED; 1.
DR Pfam; PF00112; Peptidase_C1; 1.
DR SMART; SM00645; Pept_C1; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000230066}.
FT DOMAIN 1..214
FT /note="Peptidase C1A papain C-terminal"
FT /evidence="ECO:0000259|SMART:SM00645"
SQ SEQUENCE 217 AA; 24422 MW; C851164EC0F1A819 CRC64;
MSDRICIHSN GQMKPRLSAR DLVSCCGPRG DGCNIGNAPD AWDYWKSNGI VTGGSFEEPT
GCVPYPFPKC DHYIPSTGLK PCPKKAYPTP SCQRKCQVGY NKTYDEDKFY GASSYNVHKD
EKDIMYEIMK NGPVEATFLL FVDFMYYKSG IYHTVTGGYL GRHMVRILGW GVENGVKYWL
AANSFNEQWG ENGYFRIQRG NNECGIEAEV IAGMPRI
//
