ID A0A2H1BT09_FASHE Unreviewed; 77 AA.
AC A0A2H1BT09;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Putative pre-pro-cysteine proteinase {ECO:0000313|EMBL:THD18723.1};
GN ORFNames=D915_010675 {ECO:0000313|EMBL:THD18723.1};
OS Fasciola hepatica (Liver fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Plagiorchiida; Echinostomata; Echinostomatoidea; Fasciolidae;
OC Fasciola.
OX NCBI_TaxID=6192 {ECO:0000313|EMBL:THD18723.1, ECO:0000313|Proteomes:UP000230066};
RN [1] {ECO:0000313|EMBL:THD18723.1, ECO:0000313|Proteomes:UP000230066}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Choi Y.-J., Martin J., Mitreva M.;
RT "Improved annotation for the trematode Fasciola hepatica.";
RL Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase C1 family.
CC {ECO:0000256|ARBA:ARBA00008455}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:THD18723.1}.
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DR EMBL; JXXN02008932; THD18723.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2H1BT09; -.
DR Proteomes; UP000230066; Unassembled WGS sequence.
DR GO; GO:0008234; F:cysteine-type peptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR025661; Pept_asp_AS.
DR InterPro; IPR025660; Pept_his_AS.
DR InterPro; IPR013128; Peptidase_C1A.
DR InterPro; IPR000668; Peptidase_C1A_C.
DR PANTHER; PTHR12411:SF741; CATHEPSIN K; 1.
DR PANTHER; PTHR12411; CYSTEINE PROTEASE FAMILY C1-RELATED; 1.
DR Pfam; PF00112; Peptidase_C1; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS00640; THIOL_PROTEASE_ASN; 1.
DR PROSITE; PS00639; THIOL_PROTEASE_HIS; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000230066}.
FT DOMAIN 2..71
FT /note="Peptidase C1A papain C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00112"
SQ SEQUENCE 77 AA; 8691 MW; E675B822792A0670 CRC64;
MMYRSGIYQS RTCSPFHLNH AVLAVGYGTQ GGTDYWIVKN SWGSFWGEHG YIRLARNRDN
MCGIASMASL PMVARFP
//
