ID A0A2H1UL48_9CAUD Unreviewed; 704 AA.
AC A0A2H1UL48;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=DNA polymerase {ECO:0000313|EMBL:SOP75988.1};
GN Name=g019 {ECO:0000313|EMBL:SOP75988.1};
OS Yersinia phage fPS-54-ocr.
OC Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC Autographiviridae; Studiervirinae; Helsettvirus; Helsettvirus fPS54ocr.
OX NCBI_TaxID=2052753 {ECO:0000313|EMBL:SOP75988.1, ECO:0000313|Proteomes:UP000240703};
RN [1] {ECO:0000313|Proteomes:UP000240703}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Skurnik M.;
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339,
CC Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560,
CC ChEBI:CHEBI:173112; EC=2.7.7.7;
CC Evidence={ECO:0000256|ARBA:ARBA00024632};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LT962475; SOP75988.1; -; Genomic_DNA.
DR Proteomes; UP000240703; Chromosome i.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006261; P:DNA-templated DNA replication; IEA:InterPro.
DR GO; GO:0039693; P:viral DNA genome replication; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.370; -; 2.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR019760; DNA-dir_DNA_pol_A_CS.
DR InterPro; IPR001098; DNA-dir_DNA_pol_A_palm_dom.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR002298; DNA_polymerase_A.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR10133; DNA POLYMERASE I; 1.
DR PANTHER; PTHR10133:SF62; DNA POLYMERASE THETA; 1.
DR Pfam; PF00476; DNA_pol_A; 1.
DR PRINTS; PR00868; DNAPOLI.
DR SMART; SM00482; POLAc; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS00447; DNA_POLYMERASE_A; 1.
PE 4: Predicted;
KW DNA replication {ECO:0000256|ARBA:ARBA00023109};
KW Viral DNA replication {ECO:0000256|ARBA:ARBA00023109}.
FT DOMAIN 448..664
FT /note="DNA-directed DNA polymerase family A palm"
FT /evidence="ECO:0000259|SMART:SM00482"
SQ SEQUENCE 704 AA; 78927 MW; 9E4450DADAB58BEA CRC64;
MLLTDIETNG LLPTVNKFHC AVTYDYTTDE YIKYRPQDFG AYIDALEAEV ARGGLIVFHN
GHKYDIPVIE LLAKSILGRD VSFPKENVLD TLVLSRLIFA NIKDTDAGLL RSGKLPGKRF
GSHALEAWGY RLGEMKGEYN DDFKAMLASE GVQYEDGMEW LHFNEEMMEY NVQDVVVTKA
LFEKLVCQSY YFPNESPLGH TEAERFWNGS LQCVKIEHDA AWLLAKMERN GYPVDREGLE
KLYAELAGRR GELLVDLTNT FGSWYAPKGG TEQFLHPRTG KPLSKYPRVK TPKTGDIFVA
PKNKKQREGL EPCALAKTEF MKGAPYTPVQ HVTFNPSSRD HIQRVLQLAG WIPTEFTDAG
APKVDDEVLE GVRVDDPVAQ RSIELIQEYL MLQKRIGQVA EGVNGWLRMI QEDGRIHGSV
NPNGAVTGRA THSFPNVAQV PSGKKPYGVP CRSAFGAEHN KTDGKPNPWI QVGVDASGLE
LRCLGHFMYR YDEGEYVETI LTGDIHTKNQ LAAGLPTRDN AKTFIYGFLY GAGPAKIGQI
VNGTAEDGKR LIKNFLEQTP AIAALRKAIQ SSLVESSTWR GGEQKVVWKR RWIRGLDGRK
VHVRSPHAAL NTVLQSAGAI ICKLWIIETE RLLLDAGLKH GWDGDFAYMA WVHDEIQVAC
RTREIAEIVK VKAQEAMRLV GEIFEFRCQL DTEGNIGANW NDCH
//
