ID A0A2H3B7R9_9AGAR Unreviewed; 1718 AA.
AC A0A2H3B7R9;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=FH2-domain-containing protein {ECO:0000313|EMBL:PBK66915.1};
GN ORFNames=ARMSODRAFT_959582 {ECO:0000313|EMBL:PBK66915.1};
OS Armillaria solidipes.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Marasmiineae; Physalacriaceae; Armillaria.
OX NCBI_TaxID=1076256 {ECO:0000313|EMBL:PBK66915.1, ECO:0000313|Proteomes:UP000218334};
RN [1] {ECO:0000313|Proteomes:UP000218334}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=28-4 {ECO:0000313|Proteomes:UP000218334};
RX PubMed=29085064; DOI=10.1038/s41559-017-0347-8;
RA Sipos G., Prasanna A.N., Walter M.C., O'Connor E., Balint B., Krizsan K.,
RA Kiss B., Hess J., Varga T., Slot J., Riley R., Boka B., Rigling D.,
RA Barry K., Lee J., Mihaltcheva S., LaButti K., Lipzen A., Waldron R.,
RA Moloney N.M., Sperisen C., Kredics L., Vagvoelgyi C., Patrignani A.,
RA Fitzpatrick D., Nagy I., Doyle S., Anderson J.B., Grigoriev I.V.,
RA Gueldener U., Muensterkoetter M., Nagy L.G.;
RT "Genome expansion and lineage-specific genetic innovations in the forest
RT pathogenic fungi Armillaria.";
RL Nat. Ecol. Evol. 1:1931-1941(2017).
CC -!- SIMILARITY: Belongs to the formin homology family. Diaphanous
CC subfamily. {ECO:0000256|ARBA:ARBA00008214}.
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DR EMBL; KZ293438; PBK66915.1; -; Genomic_DNA.
DR STRING; 1076256.A0A2H3B7R9; -.
DR OrthoDB; 5491813at2759; -.
DR Proteomes; UP000218334; Unassembled WGS sequence.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR015425; FH2_Formin.
DR InterPro; IPR042201; FH2_Formin_sf.
DR InterPro; IPR010472; FH3_dom.
DR InterPro; IPR014768; GBD/FH3_dom.
DR InterPro; IPR010473; GTPase-bd.
DR PANTHER; PTHR45691:SF7; FORMIN-J-LIKE; 1.
DR PANTHER; PTHR45691; PROTEIN DIAPHANOUS; 1.
DR Pfam; PF06367; Drf_FH3; 1.
DR Pfam; PF06371; Drf_GBD; 1.
DR Pfam; PF02181; FH2; 1.
DR PRINTS; PR00049; WILMSTUMOUR.
DR SMART; SM01139; Drf_FH3; 1.
DR SMART; SM01140; Drf_GBD; 1.
DR SMART; SM00498; FH2; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR PROSITE; PS51444; FH2; 1.
DR PROSITE; PS51232; GBD_FH3; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Reference proteome {ECO:0000313|Proteomes:UP000218334}.
FT DOMAIN 345..855
FT /note="GBD/FH3"
FT /evidence="ECO:0000259|PROSITE:PS51232"
FT DOMAIN 1244..1640
FT /note="FH2"
FT /evidence="ECO:0000259|PROSITE:PS51444"
FT REGION 263..289
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 309..354
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 445..483
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 922..944
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 965..989
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1091..1153
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1167..1243
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1653..1718
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 274..289
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 309..350
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 452..469
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 969..989
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1131..1153
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1171..1238
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1677..1691
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1718 AA; 188887 MW; 231E0B9BFB284292 CRC64;
MPTSSFAVPT ILTTATLHFA EVYEDATAQD VIDALIETAR AEVLGDLDDQ GWALQKIRVE
RNGRPWEEDE LEALGDGTLD PSTLVAPLVN APPTKATTQR HFSSFPMTAH LHNPVLRLVS
FHPHLSIHLS FLRVPEIHDD FRYKVFISKN TTIHDVINSV IDELGLTKSL PVPGGGNLEY
VLEEVWKDAD SEKSTRLPGS SLVFSIIESS FCANPYTSAA TRGFRFCVPD EWYRRSKSRS
VSTASTEPTQ STIRRLAALQ EFDEDEEDEG TAKMSSPEAS SLASATTGGG TISQNRLSTL
FDGWFQASPP SRSSVVSTSE KRKSIVSEPI LVESQTGNGS ITSSSSGQES DFDEGEFEDL
VNNLGLKNDK RTEMLTMSPE RKRTILSQHK LMKAGTTGSI RGPAHVQSYG PSSAAGIMPR
IVPQLTGDGL MKRFSIWGAA PAAPPVVSEE SHTSGEFDKG RKGSIDKIAE EPKPVLPQST
GGRWSSWWSL SSGDRGGVGD SRAPENSPKW YVDGLKSWKT TDIKLLKHII SLRVHLRNAS
MAWVEEFLSD EKGLDSLTVM LAGLVGKGGK RKNLTEIETN CLLEIVKCFK VFLNAGNDKS
NALFDRIIAA PMVVTYITYS LHVPSPELRT MSSEILAALS FLSADGHKAA LSALSDYRVA
YDETFRFEGL VNSLQLPSGE GEFNDDVASY LMDMDDEEVK RIWNPRAAVM SLVNALTNCP
DALEDRIVLR EEFSRRGLNE IIVALRYVKP PEYVMNQLNV YTEEKLDDDA EMRERTKGMM
RRTASDTTLS DAEDVLQDIV RLAQEHGELY PVMVDILHNY NDILGKDVEL QLKADLLTVL
DKFVEQAAML DKFDDSWHIF MKRFVASVSH ITGQELEIKA ASESDHIVEE ELESLRTKVE
ELSDERTKLK NELNQQIAEM NALKSLPPGG SQGKSSGKGG PESFHGVVQR LVQKEKQVLQ
LQSELDRIKS QQHPNEVRDA DERAKQARDR TKWNTLMDEI AKLKVKNGEA ETSLGIKDKE
IVYLKRALES VYSRFSAREE HREEAREAEM DAELMATRTI ESLSQKDDQI TSLCIEVADL
KAQVADMKAK LEAKPKTEKE FKARSPPPPP PSKPKRTSTA PTHASLAALS SKSPPPPPPP
PPPPPPPPPA RLPSIAIAAA AVLEPTSSTP LASFAPPPPP PPPPPPPPPP TAGIPVSAVS
TGPPPPPPPP PPFSLAPPPP PPPQPLGVGP PIPPPTAFRM GGVRPKVNRP AKRLKPFFWN
KINNSTVSNT VWREVSTDIQ FDLNDLETTF TIDNSTPTPS QLQANPSKKS AVTTLLDITR
ANHIAIMLKR IKLDFPGIRK ALLELNDDLS IDDLRAIGKH LPTPDEVNRI KDFGNVGKLA
MADQYFGQII SIPRLPERLD CMLYRRKLDL DIAEIRPDLN TLRNAALELR GSTKFRQILQ
AVLAVGNALN ESSFRGGAQG FQLEALLKMK ETKTAKAGTD CPTLLHYLAR VLLRSNPSLV
TFIEDLPNVE AASRLSVQTI MQSVSGMTSG LAQIKTEITR LKQQSVLPDD HFILVMQPFV
IEIEESIVAL KNMGQSLEGD LHSLLAYYGE NPDTPDAPKP EDFFGLILSF SSSLQKCALE
VHDSQQKSSV QTTQPDIQIR VEVDQPAEPT IKAAADTQGS HGRTAGGKSV GRGDLDQAIR
SMRDGKRRAR PARPLSKIFL DGAPSGGRPQ SRFLNHDA
//
