ID   A0A2H3BUG2_9AGAR        Unreviewed;       269 AA.
AC   A0A2H3BUG2;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   22-FEB-2023, entry version 14.
DE   RecName: Full=ER membrane protein complex subunit 3 {ECO:0000256|ARBA:ARBA00020822, ECO:0000256|PIRNR:PIRNR010045};
GN   ORFNames=ARMSODRAFT_1015442 {ECO:0000313|EMBL:PBK72594.1};
OS   Armillaria solidipes.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Agaricomycetidae; Agaricales; Marasmiineae; Physalacriaceae; Armillaria.
OX   NCBI_TaxID=1076256 {ECO:0000313|EMBL:PBK72594.1, ECO:0000313|Proteomes:UP000218334};
RN   [1] {ECO:0000313|Proteomes:UP000218334}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=28-4 {ECO:0000313|Proteomes:UP000218334};
RX   PubMed=29085064; DOI=10.1038/s41559-017-0347-8;
RA   Sipos G., Prasanna A.N., Walter M.C., O'Connor E., Balint B., Krizsan K.,
RA   Kiss B., Hess J., Varga T., Slot J., Riley R., Boka B., Rigling D.,
RA   Barry K., Lee J., Mihaltcheva S., LaButti K., Lipzen A., Waldron R.,
RA   Moloney N.M., Sperisen C., Kredics L., Vagvoelgyi C., Patrignani A.,
RA   Fitzpatrick D., Nagy I., Doyle S., Anderson J.B., Grigoriev I.V.,
RA   Gueldener U., Muensterkoetter M., Nagy L.G.;
RT   "Genome expansion and lineage-specific genetic innovations in the forest
RT   pathogenic fungi Armillaria.";
RL   Nat. Ecol. Evol. 1:1931-1941(2017).
CC   -!- FUNCTION: The EMC seems to be required for efficient folding of
CC       proteins in the endoplasmic reticulum (ER).
CC       {ECO:0000256|PIRNR:PIRNR010045}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the EMC3 family. {ECO:0000256|ARBA:ARBA00005376,
CC       ECO:0000256|PIRNR:PIRNR010045}.
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DR   EMBL; KZ293421; PBK72594.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2H3BUG2; -.
DR   STRING; 1076256.A0A2H3BUG2; -.
DR   OrthoDB; 167603at2759; -.
DR   Proteomes; UP000218334; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR008568; EMC3.
DR   InterPro; IPR002809; EMC3/TMCO1.
DR   PANTHER; PTHR13116:SF5; ER MEMBRANE PROTEIN COMPLEX SUBUNIT 3; 1.
DR   PANTHER; PTHR13116; UNCHARACTERIZED; 1.
DR   Pfam; PF01956; EMC3_TMCO1; 1.
DR   PIRSF; PIRSF010045; DUF850_TM_euk; 1.
DR   SMART; SM01415; DUF106; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000218334};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        17..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        131..153
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        184..202
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   269 AA;  29887 MW;  36E61C6CA88BEAA5 CRC64;
     MVNSAGSLYL DPQIRDWVLF PITLVMILVG ILRHYVVLLL QSPPKKLTRA AVREQRALAR
     SQILRATSAY SPIPPVFYQS ISKHLSDAFE AGVYLKDGPT KEGEAPSSPP NPITDPAAMD
     GMMAGMKTQM VMMVPQMVIM GWINFFFQGF VLIKLPFPLT LGFKSMLQRG IETPDMDVRW
     VSSLSWYFLN FFGLNGLYRI LLGSDNAAQD ASQTMMASPF ATAGAGQPGP QDYNKLFKGE
     KDNLAFSSGL YAWVGDDVED RVLRKYGKL
//