ID A0A2H3CAN3_9AGAR Unreviewed; 1592 AA.
AC A0A2H3CAN3;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Kinesin-like protein unc-104 {ECO:0000256|ARBA:ARBA00020751};
GN ORFNames=ARMSODRAFT_953707 {ECO:0000313|EMBL:PBK73213.1};
OS Armillaria solidipes.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Marasmiineae; Physalacriaceae; Armillaria.
OX NCBI_TaxID=1076256 {ECO:0000313|EMBL:PBK73213.1, ECO:0000313|Proteomes:UP000218334};
RN [1] {ECO:0000313|Proteomes:UP000218334}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=28-4 {ECO:0000313|Proteomes:UP000218334};
RX PubMed=29085064; DOI=10.1038/s41559-017-0347-8;
RA Sipos G., Prasanna A.N., Walter M.C., O'Connor E., Balint B., Krizsan K.,
RA Kiss B., Hess J., Varga T., Slot J., Riley R., Boka B., Rigling D.,
RA Barry K., Lee J., Mihaltcheva S., LaButti K., Lipzen A., Waldron R.,
RA Moloney N.M., Sperisen C., Kredics L., Vagvoelgyi C., Patrignani A.,
RA Fitzpatrick D., Nagy I., Doyle S., Anderson J.B., Grigoriev I.V.,
RA Gueldener U., Muensterkoetter M., Nagy L.G.;
RT "Genome expansion and lineage-specific genetic innovations in the forest
RT pathogenic fungi Armillaria.";
RL Nat. Ecol. Evol. 1:1931-1941(2017).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. {ECO:0000256|PROSITE-ProRule:PRU00283}.
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DR EMBL; KZ293421; PBK73213.1; -; Genomic_DNA.
DR STRING; 1076256.A0A2H3CAN3; -.
DR OrthoDB; 126886at2759; -.
DR Proteomes; UP000218334; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR CDD; cd22705; FHA_KIF1; 1.
DR CDD; cd01365; KISc_KIF1A_KIF1B; 1.
DR CDD; cd01233; PH_KIFIA_KIFIB; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 6.10.250.2520; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR022164; Kinesin-like.
DR InterPro; IPR022140; Kinesin-like_KIF1-typ.
DR InterPro; IPR032405; Kinesin_assoc.
DR InterPro; IPR019821; Kinesin_motor_CS.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR049780; PH_KIFIA_KIFIB.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR PANTHER; PTHR47117:SF5; -; 1.
DR PANTHER; PTHR47117; STAR-RELATED LIPID TRANSFER PROTEIN 9; 1.
DR Pfam; PF12473; DUF3694; 1.
DR Pfam; PF00498; FHA; 1.
DR Pfam; PF12423; KIF1B; 1.
DR Pfam; PF00225; Kinesin; 1.
DR Pfam; PF16183; Kinesin_assoc; 1.
DR Pfam; PF00169; PH; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00129; KISc; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS50006; FHA_DOMAIN; 1.
DR PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00283}; Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|PROSITE-ProRule:PRU00283};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00283}; Reference proteome {ECO:0000313|Proteomes:UP000218334}.
FT DOMAIN 8..366
FT /note="Kinesin motor"
FT /evidence="ECO:0000259|PROSITE:PS50067"
FT DOMAIN 513..564
FT /note="FHA"
FT /evidence="ECO:0000259|PROSITE:PS50006"
FT DOMAIN 1490..1589
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 36..56
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 708..730
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1126..1145
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 109..116
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
SQ SEQUENCE 1592 AA; 177507 MW; 7B342577902442A4 CRC64;
MAEAGDGNIK VVVRCRPLNS RELARGAKPL IRMQGNQTFL DPPEHGSQQD SKRATERKTM
AFSFDKSYWS AGPRDEPGYC SQQMLYDDLG KELLDHGFAG FNACILAYGQ TGSGKSYSMM
GYGPDKGITP LTCSELFDRV ESKKRADPNV QFTVEVSYIE IYNEKVRDLL NPKNSGNLRV
REHPSLGPYV EDLSKLMVNS YEEMMTLMDE GNKARTVAAT NMNETSSRSH AVFTLLLTMK
RHDVDTNMDT EKVSRINLVD LAGSERANST GATGQRLKEG ANINKSLTTL GKVISALAVA
SAASENKKGK KHKADEFVPY RDSVLTWLLK DSLGGNSKTA MIAAISPADY EETLSTLRYA
DQAKKIKNKA VVNEDPNAKL VRELKEELEL LRARVMGASG EDTFDPKVPP EKQKVTYQTK
DGRIKTVTKA ELQEQMETSE KLMQSLNETW EEKMQRTQEV QKEREKALEE LGITVEKNLV
GVHTPKKMPH LVNLNEDPLM SECLIYQIKP GKTMVGRLEG EKPVAIRLSG DNILEEHCYF
DNGDGKVFIY CMPDSATFLN GKQITPGQPY KLRSGFRIIL GDNHVFRFNN PEEVRKQRNR
ATMKSNLQQG FTAADLENGA ESTPVTRAES TVSSIEDDMD WTFAQREAAL ARLGLDPTLD
NLPDDDLNKL FDKITQVKTM RDHHLKPRPE SSLSQADDLW SETGRQFASD ATTDDTSVDA
LGSPEAETPL KDVQSQLENR LHAIAESSPE AEDLKVEKDH MEHQLRLVRA QMKRIIDARA
RGEAELETMD FEPVIYSARQ LRLIRKVLDK WRAHRSFSMA EVVLSNAVVV KEANIISKEL
AKDVSYNFTI ASGGSLAAPV SAVDTIAGLD QFGDVSDPVL ASATQPSVAV KILDKRHSAI
YTWSLDRLQQ QLQRMRNLTT YIDRPSYTQH FSSDEPFYDS PPPEYSFVGN ALISLAPLSR
RLSSISTVPI FCRYTSEAIG SCRIDIKIVN VVASSKYPNG SIPSTRAPSP VPATISPGSK
LSFFVTVDTV KGMSPHDFSA VHLQVRLSSF AGPTISSEEV FPSTTVDLDS GSLSELKFRR
SFSIVATSKV LTHLRQGYAP IEFFASIRST YLERLERWDE MREIKHVPRS GTSSPESETR
AASLPHMRRS ETDFVVQQTH DVVAWLQICE LAPDGQYNPV PVISQDSHDP GSFSLHQGLQ
RRIVVSLVSN SGQQFPWIEV TKVRIGNVRL LDPKGRVHES TSKATVTLPL LKDQTLEFRP
DGTGLLSAEV LWDSSVHDSV LLNRVTAANQ RILLQLNWAV AVETCSDPVQ FNADIAITMQ
TRDARPPSRF LTFLGSNKIL SKSSTLFSVR LSPPLTRSPK DLWRLDTSEK YVRGEEALGV
WKPRGISVVE DYSRLITMER RAADVQAIRV ILGASPPKPI QSDALAWRAD GLLKKSLELW
QKHFGQMGDI VLSQEPSDEE NGSSKQPADL DSLEGIKFVS ETKVVPRSDG ATKRGHLMIL
IDAGQNIWER RWFVLKRPYL HMYAHSNELE EVGVVSLTGT NVESDPQKEL LLGKPFSFTL
FTSSNSHALA APNNKELHSW VMKLDPTRLV SS
//
