ID   A0A2H3CEG1_9AGAR        Unreviewed;       795 AA.
AC   A0A2H3CEG1;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   13-SEP-2023, entry version 17.
DE   RecName: Full=AMP deaminase {ECO:0000256|ARBA:ARBA00012775};
DE            EC=3.5.4.6 {ECO:0000256|ARBA:ARBA00012775};
GN   ORFNames=ARMSODRAFT_951242 {ECO:0000313|EMBL:PBK75157.1};
OS   Armillaria solidipes.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Agaricomycetidae; Agaricales; Marasmiineae; Physalacriaceae; Armillaria.
OX   NCBI_TaxID=1076256 {ECO:0000313|EMBL:PBK75157.1, ECO:0000313|Proteomes:UP000218334};
RN   [1] {ECO:0000313|Proteomes:UP000218334}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=28-4 {ECO:0000313|Proteomes:UP000218334};
RX   PubMed=29085064; DOI=10.1038/s41559-017-0347-8;
RA   Sipos G., Prasanna A.N., Walter M.C., O'Connor E., Balint B., Krizsan K.,
RA   Kiss B., Hess J., Varga T., Slot J., Riley R., Boka B., Rigling D.,
RA   Barry K., Lee J., Mihaltcheva S., LaButti K., Lipzen A., Waldron R.,
RA   Moloney N.M., Sperisen C., Kredics L., Vagvoelgyi C., Patrignani A.,
RA   Fitzpatrick D., Nagy I., Doyle S., Anderson J.B., Grigoriev I.V.,
RA   Gueldener U., Muensterkoetter M., Nagy L.G.;
RT   "Genome expansion and lineage-specific genetic innovations in the forest
RT   pathogenic fungi Armillaria.";
RL   Nat. Ecol. Evol. 1:1931-1941(2017).
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- PATHWAY: Purine metabolism; IMP biosynthesis via salvage pathway; IMP
CC       from AMP: step 1/1. {ECO:0000256|ARBA:ARBA00004955}.
CC   -!- SIMILARITY: Belongs to the metallo-dependent hydrolases superfamily.
CC       Adenosine and AMP deaminases family. {ECO:0000256|ARBA:ARBA00006676,
CC       ECO:0000256|PIRNR:PIRNR001251}.
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DR   EMBL; KZ293418; PBK75157.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2H3CEG1; -.
DR   STRING; 1076256.A0A2H3CEG1; -.
DR   OrthoDB; 20951at2759; -.
DR   UniPathway; UPA00591; UER00663.
DR   Proteomes; UP000218334; Unassembled WGS sequence.
DR   GO; GO:0003876; F:AMP deaminase activity; IEA:UniProtKB-EC.
DR   GO; GO:0032264; P:IMP salvage; IEA:UniProtKB-UniPathway.
DR   CDD; cd01319; AMPD; 1.
DR   Gene3D; 4.10.800.20; -; 1.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   InterPro; IPR006650; A/AMP_deam_AS.
DR   InterPro; IPR006329; AMPD.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   NCBIfam; TIGR01429; AMP_deaminase; 1.
DR   PANTHER; PTHR11359; AMP DEAMINASE; 1.
DR   PANTHER; PTHR11359:SF0; AMP DEAMINASE; 1.
DR   Pfam; PF19326; AMP_deaminase; 1.
DR   PIRSF; PIRSF001251; AMP_deaminase_met; 2.
DR   SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
DR   PROSITE; PS00485; A_DEAMINASE; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000218334}.
FT   REGION          1..31
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          158..185
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   795 AA;  91576 MW;  CB044DF7BD68B5EE CRC64;
     MAALLQAEVD DIPPQAKPTT TPPPQIPESR DAFYGYPEER TFQHIEEKMW AHRRGSDARS
     DGAASFAGSM LGHGVAADAR VPSPFAEELE EEAEEAAKSA MDGHPPETVL SSELVHLFQS
     FQRCLELRDK YTRKSCQRLG DNPKDYDGYF QGLEDESADV NGVKPDASLP ARSSASDTKQ
     AKRWKVYPSP PPPHWHWTDD KEAVSVDGGY SGSGKEFKFE ECDIPGNHDW DFKIDDKGVY
     QVYEPDQATP AFDIPNIREY FVDLDYILGV ISDGPTKSYA FRRLKYLASK FTMYSLLNEF
     QELADMKRVP HRDFYNLRKV DTHVHHSSSM NQKHLLRFIK SKMKRSPQDV VIFRDSAELT
     LEQVFQSLKL TAYDLSIDTL DMHAHQDTFH RFDKFNLKYN PIGESRLREI FLKTDNFIKG
     RYLAEITKEV MTDLEQSKYQ NCEWRLSIYG RSPDEWDKLA KWIVNNKLYS HNVRWLIQVP
     RLYDVYKANG SIKTFEDIVI NVFRPLFEVT KDPTTHPELH VFLQRVVGFD TVDDESKAER
     RIYKKFPYPR VWDTNQSPPY SYWIYYMFAN MASLNNWRRL RGFNTFVFRP HCGEAGDTDH
     LTSAFLTSHS ISHGILLRKV PALQYLFYLK QIGIAMSPLS NNALFLTYER NPLPDFFKTG
     LNVSLSTDDP LQFHFTKEPL LEEYSVAAHI YKLPQSSLAE LARNSVIQSG FEMELKRHWI
     GHEWYLPGAA GNDINKTNVP NIRLSYRHQT LLEELDMICA KNHGHGSAGR RDSHGHGHGM
     LPTADNVAAR AMARH
//