ID A0A2H3CRZ4_ARMGA Unreviewed; 810 AA.
AC A0A2H3CRZ4;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=P-loop containing nucleoside triphosphate hydrolase protein {ECO:0000313|EMBL:PBK81982.1};
GN ORFNames=ARMGADRAFT_1019944 {ECO:0000313|EMBL:PBK81924.1},
GN ARMGADRAFT_1019989 {ECO:0000313|EMBL:PBK81982.1};
OS Armillaria gallica (Bulbous honey fungus) (Armillaria bulbosa).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Marasmiineae; Physalacriaceae; Armillaria.
OX NCBI_TaxID=47427 {ECO:0000313|EMBL:PBK81982.1, ECO:0000313|Proteomes:UP000217790};
RN [1] {ECO:0000313|Proteomes:UP000217790}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ar21-2 {ECO:0000313|Proteomes:UP000217790};
RX PubMed=29085064; DOI=10.1038/s41559-017-0347-8;
RA Sipos G., Prasanna A.N., Walter M.C., O'Connor E., Balint B., Krizsan K.,
RA Kiss B., Hess J., Varga T., Slot J., Riley R., Boka B., Rigling D.,
RA Barry K., Lee J., Mihaltcheva S., LaButti K., Lipzen A., Waldron R.,
RA Moloney N.M., Sperisen C., Kredics L., Vagvoelgyi C., Patrignani A.,
RA Fitzpatrick D., Nagy I., Doyle S., Anderson J.B., Grigoriev I.V.,
RA Gueldener U., Muensterkoetter M., Nagy L.G.;
RT "Genome expansion and lineage-specific genetic innovations in the forest
RT pathogenic fungi Armillaria.";
RL Nat. Ecol. Evol. 1:1931-1941(2017).
RN [2] {ECO:0000313|EMBL:PBK81982.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ar21-2 {ECO:0000313|EMBL:PBK81982.1};
RG DOE Joint Genome Institute;
RA Sipos G., Prasanna A.N., Walter M.C., O'Connor E., Balint B., Krizsan K.,
RA Kiss B., Hess J., Varga T., Slot J., Riley R., Boka B., Rigling D.,
RA Barry K., Lee J., Mihaltcheva S., LaButti K., Lipzen A., Waldron R.,
RA Moloney N.M., Sperisen C., Kredics L., Vagvolgyi C., Patrignani A.,
RA Fitzpatrick D., Nagy I., Doyle S., Anderson J., Grigoriev I.V.,
RA Guldener U., Munsterkotter M., Nagy L.G.;
RT "Lineage-specific genetic innovations streamline the genomes of Armillaria
RT species to pathogenesis.";
RL Nat. Ecol. Evol. 0:0-0(2017).
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC {ECO:0000256|ARBA:ARBA00008675}.
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DR EMBL; KZ293723; PBK81924.1; -; Genomic_DNA.
DR EMBL; KZ293723; PBK81982.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2H3CRZ4; -.
DR STRING; 47427.A0A2H3CRZ4; -.
DR InParanoid; A0A2H3CRZ4; -.
DR OMA; SKMMQGE; -.
DR OrthoDB; 35211at2759; -.
DR Proteomes; UP000217790; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF18; HEAT SHOCK PROTEIN 78, MITOCHONDRIAL; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00870; CLPAB_1; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000313|EMBL:PBK81982.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000217790}.
FT DOMAIN 119..259
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 522..666
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 696..787
FT /note="Clp ATPase C-terminal"
FT /evidence="ECO:0000259|SMART:SM01086"
FT REGION 428..449
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 432..449
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 810 AA; 89480 MW; BFCA97605A953790 CRC64;
MLRTLIKKDA SKALLLNATT ASLRPRGANF IRNPLLRQAI AWNALPSVSL GSVRHYAQPP
GGGGGGFPGF SMGPQHQKGE ALKEYSVDLT EMAKNGKLDP TIGRDEEIRR TIQILSRRTK
SNPVLIGPPG VGKTAILEGL ASRIVAKEVP ESLQNKRVLS IDLSAIMAGS GIRGQFEEKF
KALIRDIEEE ARNVICFIDE VHTLFNLGKA EGSIDAGQMI KPALARGLQL VGATTRDEYR
KTIGKDAALE RRFQPVQIDE PTVEATISIL RGLKSRYEVH HGVEISDAAL VTAAVYSARY
ISDRFLPDKA IDLVDEAASA LRLAQESKPD ELEALDRDVM TLQIELASLR NESDVFSVER
RQKVEADLAA KREEASKLTS IWKTERARLD RIKDVKERLE NAKHQLEVAQ RQGQYELASR
LRFSTIPELE RQLPDDSAER PDGESDSPLA MLHDRVTSND ISRVVAKATG IPVQSLLKGE
RDKLVHMENT LRQRVVGQDH VVHAVSDAVR ISRAGLQAPN RPVASFLFLG PTGVGKTELC
KALAGFLFND EQRGLININM SEYHDRHTIS RLIGAAPGYV GFEEGGQLTE AVRRKPYAVI
LLDELEKAHK DVSMILLQIL DEGSITDSQG RKVDFKNTII CLTSNLGSDI LAHQTSCNED
GVVTPEARDE VLERTSSYFP PELLNRLDTM LVFNKLSRQS ILQVVSLRLN DVADRLKHRR
ITLDVDEDAR GWLAKQGYSE VYGARAIARV VRTDVLFPLA QKLLRGTIRD GDTVVIRASG
EENSLLIQDN HPEDASVASE AAAKANTDLR
//
