ID A0A2H3CZ64_ARMGA Unreviewed; 339 AA.
AC A0A2H3CZ64;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Alpha/beta-hydrolase {ECO:0000313|EMBL:PBK87110.1};
GN ORFNames=ARMGADRAFT_939302 {ECO:0000313|EMBL:PBK87110.1};
OS Armillaria gallica (Bulbous honey fungus) (Armillaria bulbosa).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Marasmiineae; Physalacriaceae; Armillaria.
OX NCBI_TaxID=47427 {ECO:0000313|EMBL:PBK87110.1, ECO:0000313|Proteomes:UP000217790};
RN [1] {ECO:0000313|Proteomes:UP000217790}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ar21-2 {ECO:0000313|Proteomes:UP000217790};
RX PubMed=29085064; DOI=10.1038/s41559-017-0347-8;
RA Sipos G., Prasanna A.N., Walter M.C., O'Connor E., Balint B., Krizsan K.,
RA Kiss B., Hess J., Varga T., Slot J., Riley R., Boka B., Rigling D.,
RA Barry K., Lee J., Mihaltcheva S., LaButti K., Lipzen A., Waldron R.,
RA Moloney N.M., Sperisen C., Kredics L., Vagvoelgyi C., Patrignani A.,
RA Fitzpatrick D., Nagy I., Doyle S., Anderson J.B., Grigoriev I.V.,
RA Gueldener U., Muensterkoetter M., Nagy L.G.;
RT "Genome expansion and lineage-specific genetic innovations in the forest
RT pathogenic fungi Armillaria.";
RL Nat. Ecol. Evol. 1:1931-1941(2017).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a diacylglycerol + H2O = a fatty acid + a monoacylglycerol +
CC H(+); Xref=Rhea:RHEA:32731, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:17408, ChEBI:CHEBI:18035, ChEBI:CHEBI:28868;
CC Evidence={ECO:0000256|ARBA:ARBA00043665};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a monoacylglycerol + H2O = a fatty acid + glycerol + H(+);
CC Xref=Rhea:RHEA:15245, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:17408, ChEBI:CHEBI:17754, ChEBI:CHEBI:28868;
CC Evidence={ECO:0000256|ARBA:ARBA00043831};
CC -!- SIMILARITY: Belongs to the AB hydrolase superfamily. Lipase family.
CC Class 3 subfamily. {ECO:0000256|ARBA:ARBA00043996}.
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DR EMBL; KZ293680; PBK87110.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2H3CZ64; -.
DR STRING; 47427.A0A2H3CZ64; -.
DR InParanoid; A0A2H3CZ64; -.
DR OMA; EGAMACE; -.
DR OrthoDB; 1102158at2759; -.
DR Proteomes; UP000217790; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR CDD; cd00519; Lipase_3; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR002921; Fungal_lipase-like.
DR PANTHER; PTHR45856; ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN; 1.
DR PANTHER; PTHR45856:SF11; LIPASE_3 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF01764; Lipase_3; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:PBK87110.1};
KW Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Reference proteome {ECO:0000313|Proteomes:UP000217790};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..339
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5013924319"
FT DOMAIN 137..280
FT /note="Fungal lipase-like"
FT /evidence="ECO:0000259|Pfam:PF01764"
SQ SEQUENCE 339 AA; 35047 MW; DE3465EF70A6F116 CRC64;
MLTSALLFTF LCQFSLTVRA APGPLDFDDL LNKAGNLLDK AGGIISAGAG DAFDDIFGAS
GSNATTSVSP SDLTAAFSRP AFFSRVAYCS SASVMTFSCG APCDALVYSV KILATGGDGG
LIPRSMIAHD NLTNSIVVAH QGTDPSSIIS IANDVNLLLT PIDTESFPLA AQKNIQVHAG
FLDTFLRTAP TVLSAVKYGI STTGATTVIL TGHSLGATLA TLDALMLNDA LTHISIQTIT
FGSPRIGNQA FADFVDASFS NGSYVRMTNE ADPVPHVPPT FHVHPQGEVH LGEEGAMACE
GQENESVGCA DGVGLTASTD SIVGPYFDGI SFGQDQCLI
//
