ID A0A2H3DL62_ARMGA Unreviewed; 685 AA.
AC A0A2H3DL62;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Histone deacetylase clr3 {ECO:0008006|Google:ProtNLM};
GN ORFNames=ARMGADRAFT_994572 {ECO:0000313|EMBL:PBK91598.1};
OS Armillaria gallica (Bulbous honey fungus) (Armillaria bulbosa).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Marasmiineae; Physalacriaceae; Armillaria.
OX NCBI_TaxID=47427 {ECO:0000313|EMBL:PBK91598.1, ECO:0000313|Proteomes:UP000217790};
RN [1] {ECO:0000313|Proteomes:UP000217790}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ar21-2 {ECO:0000313|Proteomes:UP000217790};
RX PubMed=29085064; DOI=10.1038/s41559-017-0347-8;
RA Sipos G., Prasanna A.N., Walter M.C., O'Connor E., Balint B., Krizsan K.,
RA Kiss B., Hess J., Varga T., Slot J., Riley R., Boka B., Rigling D.,
RA Barry K., Lee J., Mihaltcheva S., LaButti K., Lipzen A., Waldron R.,
RA Moloney N.M., Sperisen C., Kredics L., Vagvoelgyi C., Patrignani A.,
RA Fitzpatrick D., Nagy I., Doyle S., Anderson J.B., Grigoriev I.V.,
RA Gueldener U., Muensterkoetter M., Nagy L.G.;
RT "Genome expansion and lineage-specific genetic innovations in the forest
RT pathogenic fungi Armillaria.";
RL Nat. Ecol. Evol. 1:1931-1941(2017).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; KZ293661; PBK91598.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2H3DL62; -.
DR STRING; 47427.A0A2H3DL62; -.
DR InParanoid; A0A2H3DL62; -.
DR OMA; FVSPACY; -.
DR OrthoDB; 124800at2759; -.
DR Proteomes; UP000217790; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0010468; P:regulation of gene expression; IEA:UniProt.
DR Gene3D; 3.40.800.20; Histone deacetylase domain; 1.
DR InterPro; IPR019154; Arb2-like_domain.
DR InterPro; IPR000286; His_deacetylse.
DR InterPro; IPR023801; His_deacetylse_dom.
DR InterPro; IPR037138; His_deacetylse_dom_sf.
DR InterPro; IPR023696; Ureohydrolase_dom_sf.
DR PANTHER; PTHR10625:SF4; HISTONE DEACETYLASE 6, ISOFORM G; 1.
DR PANTHER; PTHR10625; HISTONE DEACETYLASE HDAC1-RELATED; 1.
DR Pfam; PF09757; Arb2; 1.
DR Pfam; PF00850; Hist_deacetyl; 1.
DR PRINTS; PR01270; HDASUPER.
DR SUPFAM; SSF52768; Arginase/deacetylase; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000217790}.
FT DOMAIN 66..367
FT /note="Histone deacetylase"
FT /evidence="ECO:0000259|Pfam:PF00850"
FT DOMAIN 422..668
FT /note="Arb2-like"
FT /evidence="ECO:0000259|Pfam:PF09757"
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8..29
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 685 AA; 76363 MW; 37E110D3DDC1A745 CRC64;
MDAGLSVSRL TIANNDPRPP VQTSGLVRPS SPKGPRASSV PLVPSEFTVG VVYSTEMTSH
FSLQDHPEQP ARISHIWHTL IVNKCNAKMK WLPIRPVHKQ EALLVHSEDH WDKVHAIQYM
TPQQIIDSEA YYETLSLYVM QGTTRSALLS CGGVIEACLA VAASDSSLKK ALAIVRPPGH
HAEPNEHMGF CFFNNVSVAA RVVQERLKLK RILILDWDVH HGNGTQKAFN NDPSVLYISL
HRYEDGRFYP CGTFGGMQSC GEGPGLGFSV NIPWPEKGMK DADYIHAFQK IVMPIAMEFA
PQLVIISAGF DAAEGDELGE CHVSPTGYAH MTHMLSGLAS GKVVVALEGG YNIDAIAKSA
LAVTQVLLGE APPELPPMTA SESATETVWL VAKEQSKYWK SVDPKACEPR KDLERATFSI
PEILKAHRQH YLFTNYDMMQ IPLLSDYLDD RFSMQMMCTP DLLDNKTMVI FIHEFGNLRT
ELESSATCNL ELERSYLVDF SKDFIAWVKK QGYSLLDINQ FPKPFAAPTR RSQTPKDPTK
EVLVYLWDNY VQLSNAERVV LVGHGPGCQS MIDLVDQRWM LGNKLIKAVV QVVGNSKVPT
VPKSDEFKAW YSKHSLVAVP SSHPVYGNTS QGKRDLRRHH HVIAIDETQP IKLIIKALPA
IQDYVQMELA RYPLKNATAR TNNAV
//
