ID A0A2H3G2X7_FUSOX Unreviewed; 1593 AA.
AC A0A2H3G2X7;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=NACHT domain-containing protein {ECO:0000259|PROSITE:PS50837};
GN ORFNames=AU210_015976 {ECO:0000313|EMBL:PCD22178.1};
OS Fusarium oxysporum f. sp. radicis-cucumerinum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=327505 {ECO:0000313|EMBL:PCD22178.1, ECO:0000313|Proteomes:UP000219602};
RN [1] {ECO:0000313|EMBL:PCD22178.1, ECO:0000313|Proteomes:UP000219602}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Forc016 {ECO:0000313|EMBL:PCD22178.1,
RC ECO:0000313|Proteomes:UP000219602};
RX PubMed=27387256; DOI=10.1111/1462-2920.13445;
RA van Dam P., Fokkens L., Schmidt S.M., Linmans J.H., Kistler H.C., Ma L.J.,
RA Rep M.;
RT "Effector profiles distinguish formae speciales of Fusarium oxysporum.";
RL Environ. Microbiol. 18:4087-4102(2016).
RN [2] {ECO:0000313|EMBL:PCD22178.1, ECO:0000313|Proteomes:UP000219602}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Forc016 {ECO:0000313|EMBL:PCD22178.1,
RC ECO:0000313|Proteomes:UP000219602};
RX PubMed=28831051; DOI=10.1038/s41598-017-07995-y;
RA van Dam P., Fokkens L., Ayukawa Y., van der Gragt M., Ter Horst A.,
RA Brankovics B., Houterman P.M., Arie T., Rep M.;
RT "A mobile pathogenicity chromosome in Fusarium oxysporum for infection of
RT multiple cucurbit species.";
RL Sci. Rep. 7:9042-9042(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PCD22178.1}.
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DR EMBL; MABQ02000012; PCD22178.1; -; Genomic_DNA.
DR OrthoDB; 2627650at2759; -.
DR Proteomes; UP000219602; Chromosome rc.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 3.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR008906; HATC_C_dom.
DR InterPro; IPR007111; NACHT_NTPase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR012337; RNaseH-like_sf.
DR PANTHER; PTHR24184:SF11; ANK_REP_REGION DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24184; SI:CH211-189E2.2; 1.
DR Pfam; PF00023; Ank; 2.
DR Pfam; PF12796; Ank_2; 2.
DR Pfam; PF05699; Dimer_Tnp_hAT; 1.
DR Pfam; PF05729; NACHT; 1.
DR SMART; SM00248; ANK; 6.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 5.
DR PROSITE; PS50088; ANK_REPEAT; 6.
DR PROSITE; PS50837; NACHT; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000219602};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 413..568
FT /note="NACHT"
FT /evidence="ECO:0000259|PROSITE:PS50837"
FT REPEAT 892..925
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 926..959
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 960..993
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 994..1027
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1029..1055
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1063..1096
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 1334..1353
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1593 AA; 180400 MW; 034A40F5180FF9E6 CRC64;
MSSFTFPRVI ARIFVGPQRA VWYIFPICCG LLIISICLSR RRREPSRVTS APPPAEYPIQ
ILHDDNNATV DIVAVHGLAA NPDYAWVWQP KNNPPGHPGY PAKHFNWLKE LLPIELSSAQ
LSCRVMTFNY DSKWFMNAPQ QRLSNISDTL LVSLRNKRDK ATGRPLIFIG HSFGGNLIEQ
AIISASRQSG YLEIAESTVG VVFLGTPHRG SAAASWGVLI TSLAPPQFTA EKRILKDLEE
QSSSLTDRLH DFSRWLFVES VPVVCFFEQL ATDYSSRMGA MGQVIPYKEL VVPETSACID
GHPKISLHAD HFKINKFYGP DDPSFKLVYP EIERMARGAQ DILNHHRNPK AIPMDQSATS
GDLRTCLQEM RVTNPRDILS EIRSQKGKRI GHTCEWILKR EEFSAWGAND NSQLLRLIGS
PGIGKTMMST FLIEALKGKV EKSPDKMFAY FLCDYRYPEQ RSPTAILRSL IWQLLLQRNG
FFRHIRSDFE KHKDSRLFES LFENFSTLWR IFQDMLRDEH AGEVFILIDA LDECDRSTRK
ALLRCMRELF QASLKSAGNF KFLVTCRPEI SDIEYELIGI DVSLRMDSSE VNADLSDYIN
FKGEDLAQRK GYSQNLKEDV KAALESRAGG TFLWVSLMIN ELESTPNYEV ADKLKDLPEG
LDETYTRILE DNIPKKRRED ARFLLLSMVA ARRPLTKKEL AASFAFWKTG SVVGHHDLHD
YMDICASCSS IIHLDVARNN GETTANFCHQ SVKDFLLNDH GSLSGAWYQM SSDGANLHMF
QMCWCYLSSD VFFHGRLVIS RRNNMLLKTP IEELKTHLDQ YPFLEYASRE WEEHAIASYP
ALLKDLKIDI VKAPILRDVW FLRTAREGHG HEAVFKLLLI TEGADVNSKD KNGRTPLSLA
AMYGHEGIVK MLLATEGVDM DSKDNDGRTP LSLAVMYEHD AIVKLLLATE GVDMDSKDKN
GQTPLSLATQ DGREIIVKLL LATEKVDVNS KDKGGDTPLL LATESRHEAI VKMLIATEGI
DVNAKDEVYG VTPLSLAAKN GYETIVKLLL AADKDDVDSK DKDGQTPLSL AAENGHKAIV
KLLLATEKVD VNSKDKGGDT PLSDTLDAAS IKAESGRTTL ADLPTVQIGC KRYIPEEYIA
NKNRKGRRSW IQAYGFFLTE VSPDLRTLQT YWACSKCDER GKSSLFVATN TTSPIEHLRR
SHMMTEADGN AYEDSSRADS QPPSKRRCLE LPTARSNVNK AKELTVGWIV TANLPFTAPS
NPYLRRMLDL HDASLAKEIT MRCQGWAKEG RYGALWEVMI GMEYLLNFFE EQKLIFSPPD
GTADELQIAR ASATTRCSPP RADQGRGREK HLPQHTRDEY TGAFSQAESL DDDHRRCIQI
SINNCWSKLD EYYSLLGQSP LYPAAVILHP RWNVSWLEAN WTSHEQLVWL RDAKNSVREF
FEQQYPRKEQ SEAARTMIGK AMRQDEPSQF DQWMQSYDRY MMEEEDELGV YMRQGPVRRE
NLNPILWWKE HQEEYPRLSK FALDILAIPA MSVDPERTFS VTKLTISSQR HSLSPEIIEE
IQCLRNWLGH QAITVGEVVS FGGDLMGWDG GEA
//
