ID A0A2H3H1T0_FUSOX Unreviewed; 1079 AA.
AC A0A2H3H1T0;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=Importin N-terminal domain-containing protein {ECO:0000259|PROSITE:PS50166};
GN ORFNames=AU210_010877 {ECO:0000313|EMBL:PCD31219.1};
OS Fusarium oxysporum f. sp. radicis-cucumerinum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=327505 {ECO:0000313|EMBL:PCD31219.1, ECO:0000313|Proteomes:UP000219602};
RN [1] {ECO:0000313|EMBL:PCD31219.1, ECO:0000313|Proteomes:UP000219602}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Forc016 {ECO:0000313|EMBL:PCD31219.1,
RC ECO:0000313|Proteomes:UP000219602};
RX PubMed=27387256; DOI=10.1111/1462-2920.13445;
RA van Dam P., Fokkens L., Schmidt S.M., Linmans J.H., Kistler H.C., Ma L.J.,
RA Rep M.;
RT "Effector profiles distinguish formae speciales of Fusarium oxysporum.";
RL Environ. Microbiol. 18:4087-4102(2016).
RN [2] {ECO:0000313|EMBL:PCD31219.1, ECO:0000313|Proteomes:UP000219602}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Forc016 {ECO:0000313|EMBL:PCD31219.1,
RC ECO:0000313|Proteomes:UP000219602};
RX PubMed=28831051; DOI=10.1038/s41598-017-07995-y;
RA van Dam P., Fokkens L., Ayukawa Y., van der Gragt M., Ter Horst A.,
RA Brankovics B., Houterman P.M., Arie T., Rep M.;
RT "A mobile pathogenicity chromosome in Fusarium oxysporum for infection of
RT multiple cucurbit species.";
RL Sci. Rep. 7:9042-9042(2017).
CC -!- FUNCTION: tRNA nucleus export receptor which facilitates tRNA
CC translocation across the nuclear pore complex. Involved in pre-tRNA
CC splicing, probably by affecting the interaction of pre-tRNA with
CC splicing endonuclease. {ECO:0000256|ARBA:ARBA00025147}.
CC -!- SIMILARITY: Belongs to the exportin family.
CC {ECO:0000256|ARBA:ARBA00009466}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PCD31219.1}.
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DR EMBL; MABQ02000007; PCD31219.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2H3H1T0; -.
DR STRING; 327505.A0A2H3H1T0; -.
DR OrthoDB; 169519at2759; -.
DR Proteomes; UP000219602; Chromosome 9.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0005049; F:nuclear export signal receptor activity; IEA:InterPro.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006611; P:protein export from nucleus; IEA:InterPro.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR041123; CRM1_repeat.
DR InterPro; IPR041235; Exp1_repeat_2.
DR InterPro; IPR013598; Exportin-1/Importin-b-like.
DR InterPro; IPR001494; Importin-beta_N.
DR InterPro; IPR045065; XPO1/5.
DR InterPro; IPR014877; XPO1_C_dom.
DR InterPro; IPR040485; XPO1_repeat_3.
DR PANTHER; PTHR11223; EXPORTIN 1/5; 1.
DR PANTHER; PTHR11223:SF2; EXPORTIN-1; 1.
DR Pfam; PF08767; CRM1_C; 1.
DR Pfam; PF18777; CRM1_repeat; 1.
DR Pfam; PF18784; CRM1_repeat_2; 1.
DR Pfam; PF18787; CRM1_repeat_3; 1.
DR Pfam; PF03810; IBN_N; 1.
DR Pfam; PF08389; Xpo1; 1.
DR SMART; SM01102; CRM1_C; 1.
DR SMART; SM00913; IBN_N; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000219602};
KW Transport {ECO:0000256|ARBA:ARBA00022448};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT DOMAIN 26..92
FT /note="Importin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50166"
FT REGION 1053..1079
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1053..1073
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1079 AA; 123695 MW; CDD7F2C44E97052F CRC64;
MAASIEELDV LVRSFYEGRG EQQKAAQAAL NQFKEDPDAW LMVDKILSDA QYPQTKYLGL
QVLDNVILTR WKVLPREQCQ GIRNFIVQFI IQCSSTEESL RQQKTLLNKL NLVLVSVLKQ
EWPHNWPTFI NEIISSCHSN LSICENNMII LRLLSEEVFD YSAEQMTSTK TRNLKQTMCA
EFSQIFNLCQ EVLNTATQPS LIKATLETLL RFCNWIPLGY IFETPLIETL RTRFLSTPEF
RNVTMQCLTE IGGLQTGGPG QPNSYDEQLV KMFTETLTTI ANIIPVSLDL KSTYPSSNSR
DQEFIQNLAL FLCNFFGMHL NLIEKLPNRD FLIHGHYYLI RISQIDDREI FKICLDYWLK
LVQELYEEMQ QLPMTDLNPL MAVGAGMSGS GAPNPTMLNN YPLRKHKYNE VLSNLRVVMI
EKMVRPEEVL IVENDEGEIV REFVKESDTV QLYKTIRECL VYLTHLDVVD TENIMTEKLA
RQVDGSEWSW HNCNVLCWAI GSISLAMNEE TEKRFLVTVI KDLLGLTEMK RGKDNKAVVA
SNIMYIVGQY PRFLKAHWKF LKTVVNKLFE FMHESHEGVQ DMACDTFIKI ARQCRRHFVA
LQPSEQEPFI EEIVRNMGKI TCDLTPQQVH TFYEACGYMV AAQGNKHQQE RLLADLMAIP
NAAWDEIIKQ ATVNPTILQD AETIKVIGNI MKTNVSACSS VGSYFYPQIG RIYHDMLQMY
NATSTLISEA VARDGELATK MPKVRGLRTI KKEILKLIEV YVDKAEDLQA VRAQMVPPLL
ESVLVDYNRN VPGARDAEVL KACSTIITKL SALMEDQVPT IMQNVFECTL EMINKDFSEF
PEHRVEFFNL LRAINLHCFP ALLKLDNNQF KFVIDSCSWA FKHDNRDVEA AGLNMALELI
NNIAEKTDVQ TANAFFQRFF ITILQDVFFV VTDNDHKAGF KTQSMLLMKL FYYINPADGS
QPKIQGPIYS PDQAQAGTDN REFVANFVAN LLQNAFRNLQ ANQITSFVEG LFTLNTQYDK
FRLNLRDFLV SLKEFAGDNA ELFIVEKEQQ EQDAKAADME RRQKVGGLLK PSELDDEEL
//
