ID A0A2H3HLG4_FUSOX Unreviewed; 1428 AA.
AC A0A2H3HLG4;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=CCR4-NOT transcription complex subunit 4 {ECO:0008006|Google:ProtNLM};
GN ORFNames=AU210_002528 {ECO:0000313|EMBL:PCD43431.1};
OS Fusarium oxysporum f. sp. radicis-cucumerinum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=327505 {ECO:0000313|EMBL:PCD43431.1, ECO:0000313|Proteomes:UP000219602};
RN [1] {ECO:0000313|EMBL:PCD43431.1, ECO:0000313|Proteomes:UP000219602}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Forc016 {ECO:0000313|EMBL:PCD43431.1,
RC ECO:0000313|Proteomes:UP000219602};
RX PubMed=27387256; DOI=10.1111/1462-2920.13445;
RA van Dam P., Fokkens L., Schmidt S.M., Linmans J.H., Kistler H.C., Ma L.J.,
RA Rep M.;
RT "Effector profiles distinguish formae speciales of Fusarium oxysporum.";
RL Environ. Microbiol. 18:4087-4102(2016).
RN [2] {ECO:0000313|EMBL:PCD43431.1, ECO:0000313|Proteomes:UP000219602}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Forc016 {ECO:0000313|EMBL:PCD43431.1,
RC ECO:0000313|Proteomes:UP000219602};
RX PubMed=28831051; DOI=10.1038/s41598-017-07995-y;
RA van Dam P., Fokkens L., Ayukawa Y., van der Gragt M., Ter Horst A.,
RA Brankovics B., Houterman P.M., Arie T., Rep M.;
RT "A mobile pathogenicity chromosome in Fusarium oxysporum for infection of
RT multiple cucurbit species.";
RL Sci. Rep. 7:9042-9042(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PCD43431.1}.
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DR EMBL; MABQ02000002; PCD43431.1; -; Genomic_DNA.
DR STRING; 327505.A0A2H3HLG4; -.
DR OrthoDB; 1748at2759; -.
DR Proteomes; UP000219602; Chromosome 2.
DR GO; GO:0030014; C:CCR4-NOT complex; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR CDD; cd16618; mRING-HC-C4C4_CNOT4; 1.
DR CDD; cd12438; RRM_CNOT4; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR034261; CNOT4_RRM.
DR InterPro; IPR039780; Mot2.
DR InterPro; IPR039515; NOT4_mRING-HC-C4C4.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR003954; RRM_dom_euk.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR12603; CCR4-NOT TRANSCRIPTION COMPLEX RELATED; 1.
DR PANTHER; PTHR12603:SF0; CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 4; 1.
DR Pfam; PF00076; RRM_1; 1.
DR Pfam; PF14570; zf-RING_4; 1.
DR SMART; SM00361; RRM_1; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50102; RRM; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Reference proteome {ECO:0000313|Proteomes:UP000219602};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00175}.
FT DOMAIN 15..58
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 121..207
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 231..643
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 655..909
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 966..1133
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 82..109
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1391..1418
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 240..271
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 282..357
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 385..424
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 458..499
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 507..580
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 612..627
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 748..765
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 825..842
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 844..908
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 966..995
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1067..1084
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1101..1130
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1428 AA; 153239 MW; B2DB55F36353986E CRC64;
MAPQDSFIED EEDTCPLCIE EFDLSDRNFR PCPCGYQVCQ FCFNNIKNNM NGLCPACRRP
YDEKTIQWKV VTQEEVAEFR ANIQKNQKKR ALDQRQKELQ KREAEKENRK NLIGVRVVQK
NLVYITGLAP TVREDELLKT LRKPEFFGQY GNIQKISISN RKSSDGQHQS LGIYVTFERP
EEATRCIQAV HGSHNGDRVL KAQHGTTKYC SAWLKNEKCG NPGCMFLHEQ GDEEDSYSRQ
DLSSMNSIGS QRPLPGGSSR SASRQQISHP TPPPVVSHPM TRSISKEGSE NGADGSALPS
SANWARNPQR SRRGSLATSG AASSPAISTA QPQEEPVAGP SSSRTRESES PAPTQESPDS
WLKEIYKTLQ SCPMPIFPDV DEDQYPPMFD PRGGEKRRAM REEEDSRLSG EQEERPEVRE
PSEGEPETGG SLALGGEPED RDSSGDNRGF DRRPSAQPPI QRLSTDGLFG PSLTGASPFG
QSSGNPGSRS MTPQQLYLRS QGGFGDAPPG ITSQSNAFQN QGQSQGQGHN RQSSRFSFAN
DNAGSSTNVK VAANPRIMAQ QSSMMPNTFQ SQSSNQFYGA SMPGPPPGLK STGTPPSMFG
QFGGQGFGAP KDNSSELLQS LIGRGRAGNN QSHDAGKHDE LPSLDEATNS VDALVSDDPI
LPPIGLEGRT SVPPGLSLPP GLPANISRPP STQGHTKPTN IVPALPRMPP PGLSQGSLTP
DQSPAKLKPA IPVSEAKKNI KSLAAESGLS REITTQSQPN LTKASFLQDE DFPALDASKN
KSRPATPTPK ATPKAKRHAE RIVDRMMAKA GASLESMAQA TKAEEAKVQE TKAQEVEAQE
TKAQEVKPAS SSQAADKKPI TVNTQVGKNV AVKTSELSAT TEKSTTETSA AFPPLPTPSS
TAIASPVTRT APKTLRVIAA PKAEAPPPAS PALTMASVAL SGTSRAVSGS YRPDTPVSEM
ISDNASVVSA SVTHSRASSP PPSRIGSAAV RTTTKSQQRK QRKDVLKQET KLIAEAPIAE
AEVHAPIMGR KKKQKKEKPI KTAQPDASTI PEAPADEPSQ PPSQQEPVKE PEREPEEKPL
KSKNSQKKSI KSKGKTKEVE TQPTPPPPPP ASPKESTPDA QEPPARPQPD PASVFSEIKN
TLWASSVDKL QLFKPIANGS SRTDYSAAKN NANKAEHCKD CSCKCGEIQD EDLAALRAGK
PVRKQFHVDG SRMLITPNGD CIRGLTPEEE DAFLELQAAI ANTAENPGSF IAPRHQPGSG
AFSLIKGRAV PNGRPNIFPA TAQLQSQDPI GKLQREDALS YINQYVLPRL NLGATNMGFP
KGASPTKDAA AASLNSLAPY FYGPDAAAGV GIYSPPDGAR AMQDFSSAGM SSEERGKNFG
MGVGGMPLMS VEDAEGALAA ARRETEKLEK GLNQVIKRNR RLILGGNN
//
