ID A0A2H3HUE0_FUSOX Unreviewed; 627 AA.
AC A0A2H3HUE0;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 22-FEB-2023, entry version 13.
DE RecName: Full=Adenosine deaminase domain-containing protein {ECO:0000259|Pfam:PF00962};
GN ORFNames=AU210_002956 {ECO:0000313|EMBL:PCD43868.1};
OS Fusarium oxysporum f. sp. radicis-cucumerinum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=327505 {ECO:0000313|EMBL:PCD43868.1, ECO:0000313|Proteomes:UP000219602};
RN [1] {ECO:0000313|EMBL:PCD43868.1, ECO:0000313|Proteomes:UP000219602}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Forc016 {ECO:0000313|EMBL:PCD43868.1,
RC ECO:0000313|Proteomes:UP000219602};
RX PubMed=27387256; DOI=10.1111/1462-2920.13445;
RA van Dam P., Fokkens L., Schmidt S.M., Linmans J.H., Kistler H.C., Ma L.J.,
RA Rep M.;
RT "Effector profiles distinguish formae speciales of Fusarium oxysporum.";
RL Environ. Microbiol. 18:4087-4102(2016).
RN [2] {ECO:0000313|EMBL:PCD43868.1, ECO:0000313|Proteomes:UP000219602}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Forc016 {ECO:0000313|EMBL:PCD43868.1,
RC ECO:0000313|Proteomes:UP000219602};
RX PubMed=28831051; DOI=10.1038/s41598-017-07995-y;
RA van Dam P., Fokkens L., Ayukawa Y., van der Gragt M., Ter Horst A.,
RA Brankovics B., Houterman P.M., Arie T., Rep M.;
RT "A mobile pathogenicity chromosome in Fusarium oxysporum for infection of
RT multiple cucurbit species.";
RL Sci. Rep. 7:9042-9042(2017).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PCD43868.1}.
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DR EMBL; MABQ02000002; PCD43868.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2H3HUE0; -.
DR STRING; 327505.A0A2H3HUE0; -.
DR OrthoDB; 4403at2759; -.
DR Proteomes; UP000219602; Chromosome 2.
DR GO; GO:0019239; F:deaminase activity; IEA:InterPro.
DR Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR InterPro; IPR001365; A_deaminase_dom.
DR InterPro; IPR006330; Ado/ade_deaminase.
DR InterPro; IPR032466; Metal_Hydrolase.
DR PANTHER; PTHR11409:SF37; A_DEAMINASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11409; ADENOSINE DEAMINASE; 1.
DR Pfam; PF00962; A_deaminase; 1.
DR SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000219602}.
FT DOMAIN 290..603
FT /note="Adenosine deaminase"
FT /evidence="ECO:0000259|Pfam:PF00962"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 12..28
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 627 AA; 72117 MW; AD2D796355CC4BCD CRC64;
MGALCSRTEP VEGAQDDYDQ HHRKDHSHTD FMTRLSKRAK ISRMGEPALD DAAAARNHIQ
AHDAEITARG VLIEKADVTD TVTQEPGVVG EYFKLRQQMV AREKALDFDH GCRMRSTPEE
RRADAIIQRL RSEDEENVYA QAAPRTGYGG QQHPRFPGDH FLSNKHLIDQ TSLFRVAQHM
PKGSHLHIHF NACLAPQVLL NLAKEMGRMF ITSDIPLVSD NDFINFDRCE IQFSLLSPEK
ETPGDLFSQT YQPRQTMRFR DFLDRFPGYY ATDSTNVDEW LFEKLMFHEE EAHNHLQTAS
GAWEKFNGRT RMMKGLFNYA TAYRRYTRLC LEDFMKDNIS YAEIRPNFMT SNQLWSDDGT
QLIDNKGIME LIIEEVINFQ TDMKKQGKFF GGLKVIYCTP RSFAPAQIDA ALTECLKFKQ
IWPEWIAGFD LVGEESKGRP IKDFIPELLK FQENCDRDGV EIPFLFHCGE TLDMGTDTDG
NLVDALLLKS KRIGHGFALA KHPYVMQHMK ERGVCLELCP ISNEILGLTP RVSAHTMYQL
LANNVHCTVS SDNGTLFRSS LSHDFYQVLV GKADMGLFGW KQLALWSLEH ACLSESEYNR
VFSDWEQKWK EFIKWMIEEY GEQPKVV
//
