ID A0A2H3HVU1_FUSOX Unreviewed; 875 AA.
AC A0A2H3HVU1;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=Importin N-terminal domain-containing protein {ECO:0000259|PROSITE:PS50166};
GN ORFNames=AU210_002656 {ECO:0000313|EMBL:PCD43564.1};
OS Fusarium oxysporum f. sp. radicis-cucumerinum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=327505 {ECO:0000313|EMBL:PCD43564.1, ECO:0000313|Proteomes:UP000219602};
RN [1] {ECO:0000313|EMBL:PCD43564.1, ECO:0000313|Proteomes:UP000219602}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Forc016 {ECO:0000313|EMBL:PCD43564.1,
RC ECO:0000313|Proteomes:UP000219602};
RX PubMed=27387256; DOI=10.1111/1462-2920.13445;
RA van Dam P., Fokkens L., Schmidt S.M., Linmans J.H., Kistler H.C., Ma L.J.,
RA Rep M.;
RT "Effector profiles distinguish formae speciales of Fusarium oxysporum.";
RL Environ. Microbiol. 18:4087-4102(2016).
RN [2] {ECO:0000313|EMBL:PCD43564.1, ECO:0000313|Proteomes:UP000219602}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Forc016 {ECO:0000313|EMBL:PCD43564.1,
RC ECO:0000313|Proteomes:UP000219602};
RX PubMed=28831051; DOI=10.1038/s41598-017-07995-y;
RA van Dam P., Fokkens L., Ayukawa Y., van der Gragt M., Ter Horst A.,
RA Brankovics B., Houterman P.M., Arie T., Rep M.;
RT "A mobile pathogenicity chromosome in Fusarium oxysporum for infection of
RT multiple cucurbit species.";
RL Sci. Rep. 7:9042-9042(2017).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the importin beta family. Importin beta-1
CC subfamily. {ECO:0000256|ARBA:ARBA00010907}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PCD43564.1}.
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DR EMBL; MABQ02000002; PCD43564.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2H3HVU1; -.
DR STRING; 327505.A0A2H3HVU1; -.
DR OrthoDB; 124901at2759; -.
DR Proteomes; UP000219602; Chromosome 2.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR021133; HEAT_type_2.
DR InterPro; IPR001494; Importin-beta_N.
DR InterPro; IPR040122; Importin_beta.
DR PANTHER; PTHR10527; IMPORTIN BETA; 1.
DR PANTHER; PTHR10527:SF1; IMPORTIN SUBUNIT BETA-1; 1.
DR Pfam; PF13513; HEAT_EZ; 1.
DR Pfam; PF03810; IBN_N; 1.
DR SMART; SM00913; IBN_N; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50077; HEAT_REPEAT; 1.
DR PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000219602}.
FT DOMAIN 24..105
FT /note="Importin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50166"
FT REPEAT 413..451
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
SQ SEQUENCE 875 AA; 96036 MW; 1715C46346D40C5B CRC64;
MSSSEINQVL ANSLSPDANL RNAAEQQLTQ AAESNFPLYL ATLVQELAND SADGSIRAAA
GIALKNAFTT RDFARHQELQ AKWLQQTDDE TKNRVKELTL QTLNSSNTQA GTAAAQVISS
IAAIELPRGQ WNDLLPFLVK NVSEGADHQK QSSLTTIGYI CESQDAELRG ALVTHSNAIL
TAVVQGARKE ETNIEVRLAA ITALGDSLEF VGNNFKHEGE RNYIMQVVCE ATQADDSRIQ
QGAFGCLNRI MALYYENMRF YMEKALFGLT ILGMKSDDED VAKLAVEFWS TVCEEEISIE
DDNAQVESSD QMRPFYNFAR VAANEVVPVL LLLLTKQDED ATDDEYNLSR AAYQCLQLYA
QAVGATIITP VLQFVEGNLR HEDWHNRDAA VSAFGAIMEG PDEKVLDPIV KQALPILITM
MDDQSLHVKD STAYALGRIT EACSEAIDPQ TQLPTLIESL FKGLLSSAKM APSCCWALMN
LAERFAGDLG ASSNAITPHF NNAVSSLLDV TARTETETSV RTAAYEVLNV FVQNAASESL
QPVASLSDVI IKRLEETVPL QNQVVSVEDK ITLEEMQNSL CTVLQAIISR LDKEIIPQGD
RIMQILLQIL NSVGGKSSVP DAVFATISAL STAMEEDFVK YMDAFAPFLY NALGNQDEPS
LCSMAIGLVS DITRSLGERS QPYCDNFMNY LLNNLRSTTL ANQFKPAILQ CFGDIAGAIG
GHFETYLSVV AQVLEQATTV TASPEGPYEM YDYVVSLREG IMDAWGGIIG AMKVSEKTQA
LQQYVPLIFN ALSIIASDMN RSESLMRASM GVIGDLADAY PDGQLVDAFR QDWLTVMIKE
TKTNREFQPR TIETARWARE QVKRQLGGSQ AVMAN
//
