ID   A0A2H3HZJ7_9EURO        Unreviewed;       489 AA.
AC   A0A2H3HZJ7;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=Magnesium transporter {ECO:0000256|RuleBase:RU366042};
GN   ORFNames=PENO1_108050 {ECO:0000313|EMBL:PCG88831.1};
OS   Penicillium occitanis (nom. inval.).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX   NCBI_TaxID=290292 {ECO:0000313|EMBL:PCG88831.1, ECO:0000313|Proteomes:UP000218381};
RN   [1] {ECO:0000313|EMBL:PCG88831.1, ECO:0000313|Proteomes:UP000218381}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CL100 {ECO:0000313|EMBL:PCG88831.1,
RC   ECO:0000313|Proteomes:UP000218381};
RX   PubMed=28951729; DOI=10.3389/fmicb.2017.01627;
RA   Bravo-Ruiz G., Sassi A.H., Marcet-Houben M., Di Pietro A., Gargouri A.,
RA   Gabaldon T., Roncero M.I.G.;
RT   "Regulatory Mechanisms of a Highly Pectinolytic Mutant of Penicillium
RT   occitanis and Functional Analysis of a Candidate Gene in the Plant Pathogen
RT   Fusarium oxysporum.";
RL   Front. Microbiol. 8:1627-1627(2017).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Mitochondrion
CC       inner membrane {ECO:0000256|RuleBase:RU366042}; Multi-pass membrane
CC       protein {ECO:0000256|RuleBase:RU366042}.
CC   -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35)
CC       family. {ECO:0000256|ARBA:ARBA00009765, ECO:0000256|RuleBase:RU366042}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PCG88831.1}.
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DR   EMBL; NPFK01000725; PCG88831.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2H3HZJ7; -.
DR   STRING; 290292.A0A2H3HZJ7; -.
DR   OrthoDB; 73031at2759; -.
DR   Proteomes; UP000218381; Unassembled WGS sequence.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006811; P:monoatomic ion transport; IEA:UniProtKB-KW.
DR   CDD; cd12823; Mrs2_Mfm1p-like; 1.
DR   Gene3D; 2.40.128.330; -; 1.
DR   Gene3D; 1.20.58.340; Magnesium transport protein CorA, transmembrane region; 1.
DR   InterPro; IPR039204; MRS2-like.
DR   PANTHER; PTHR13890:SF26; MAGNESIUM TRANSPORTER MRS2 HOMOLOG, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR13890; RNA SPLICING PROTEIN MRS2, MITOCHONDRIAL; 1.
PE   3: Inferred from homology;
KW   Ion transport {ECO:0000256|RuleBase:RU366042};
KW   Magnesium {ECO:0000256|RuleBase:RU366042};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU366042};
KW   Mitochondrion {ECO:0000256|RuleBase:RU366042};
KW   Mitochondrion inner membrane {ECO:0000256|RuleBase:RU366042};
KW   Reference proteome {ECO:0000313|Proteomes:UP000218381};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU366042};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU366042};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU366042}.
FT   TRANSMEM        325..343
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU366042"
FT   TRANSMEM        355..377
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU366042"
FT   REGION          439..489
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        461..475
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   489 AA;  54069 MW;  FE4F82383FDE8124 CRC64;
     MACSENLNTA KVISATYLTH DTLGSDKESY QKWKNSTSPP ITSFTDDGAE GNLFNLGRTL
     ASKTLDEPRL RCTEFDENGN VTLVNGEFRK SELIAKYGLL NRDLRKIDSS VLPHILVRPS
     TILISLLHLR VLIKADRVLV FDAYGSADSY TQSVFMYDLE GKLRQRQAPG SGALPYELRA
     LESVLISVTS GLESEFEGVR DPVVRVLRAL EEDIDRDKLR HLLVYSKKLG SFEQKARLVR
     DAIDDLLEAD DDLAAMYLSD RAHGKVRAEN DHQEVEMLLE SYHKICDEIV QASGNLVTAI
     RNTEEVVKAI LDANRNSLML LDLKFSIGTL GLAAGTLISA LYGMNLKNFI EESDFGFGAV
     SITCFISSII VSLYGLAKLR KVQRVRMWGE GMDTAGMGPL QSRSLALTNR GNWRSDAIEP
     MLAGLPGEGR SERLKRFKEA VKSAAKGDSP TDAARRMAIS QARRTASQSQ DKNGTKPEEN
     TSDETIPKA
//