ID A0A2H3I7U1_FUSOX Unreviewed; 1166 AA.
AC A0A2H3I7U1;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=DUF726 domain protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=AU210_001159 {ECO:0000313|EMBL:PCD45729.1};
OS Fusarium oxysporum f. sp. radicis-cucumerinum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=327505 {ECO:0000313|EMBL:PCD45729.1, ECO:0000313|Proteomes:UP000219602};
RN [1] {ECO:0000313|EMBL:PCD45729.1, ECO:0000313|Proteomes:UP000219602}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Forc016 {ECO:0000313|EMBL:PCD45729.1,
RC ECO:0000313|Proteomes:UP000219602};
RX PubMed=27387256; DOI=10.1111/1462-2920.13445;
RA van Dam P., Fokkens L., Schmidt S.M., Linmans J.H., Kistler H.C., Ma L.J.,
RA Rep M.;
RT "Effector profiles distinguish formae speciales of Fusarium oxysporum.";
RL Environ. Microbiol. 18:4087-4102(2016).
RN [2] {ECO:0000313|EMBL:PCD45729.1, ECO:0000313|Proteomes:UP000219602}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Forc016 {ECO:0000313|EMBL:PCD45729.1,
RC ECO:0000313|Proteomes:UP000219602};
RX PubMed=28831051; DOI=10.1038/s41598-017-07995-y;
RA van Dam P., Fokkens L., Ayukawa Y., van der Gragt M., Ter Horst A.,
RA Brankovics B., Houterman P.M., Arie T., Rep M.;
RT "A mobile pathogenicity chromosome in Fusarium oxysporum for infection of
RT multiple cucurbit species.";
RL Sci. Rep. 7:9042-9042(2017).
CC -!- SIMILARITY: Belongs to the TMCO4 family.
CC {ECO:0000256|ARBA:ARBA00009824}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PCD45729.1}.
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DR EMBL; MABQ02000001; PCD45729.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2H3I7U1; -.
DR OrthoDB; 8526at2759; -.
DR Proteomes; UP000219602; Chromosome 1.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR007941; DUF726.
DR PANTHER; PTHR17920:SF24; LIPASE MIL1-RELATED; 1.
DR PANTHER; PTHR17920; TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 TMCO4; 1.
DR Pfam; PF05277; DUF726; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000219602};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 559..583
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 603..624
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..239
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 424..465
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 954..978
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1020..1166
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 67..87
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 120..163
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 179..193
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 215..239
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 424..440
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 954..975
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1028..1044
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1045..1059
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1060..1076
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1093..1109
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1121..1143
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1146..1160
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1166 AA; 127824 MW; 4AF0539515DF71D5 CRC64;
MTTPAEVDDF GLPIRRFPTP KNDEPTETPK DEKPAASPVA DALSGEQPRA SETKNDKSSD
QTTPPAVEPV KDDDKSETFE DARSEQSNPS KDASNPPVVT HETPPPTFIK TPAKIEPAEP
ESINDPEPKD SRKTRSETPE APKEPTDVDV AIKKQETPKP DDPTNKGPVE TQPEAADPVK
KSTGDEVAVS KEEPPQPDKV TPTPVSPTQA NRKDVSEFSH QKISTKPEEP QKGVDDDDWQ
EMPSYARYDM YNDDDKLVAR EYDPEQDESY EYGGLGGAGK GYTRVTLDDD AESATSMDDN
TKYLFKSAAG TSMVDDDEGR DAIGQMQATK DLLTEGQRVA YVGLVRLEIV RLVKEAEKMK
SFKKTKKEVG VSVESMLMWG QKMMLRLYAH MEINEAEQIM IEQLAEHGVM PQDLAPALNT
NARVSNPMAD SESSMPSTPS LDEKPAEAPP PYEALDGEEL SDVKTPSQLP TTAKIDIDLR
WTVLCDLFLL LIADSIYDSR SRVLLERVGE SLDITWVDIC RFEKKVTEAL EMQQAAEKEN
WNEEEHTETR RKNALTRRYV MMGLATVGGG LVIGLSAGLL APVIGAGLAT GLTAIGVTGT
GSFLGGVGGA AIITSGAAAS GSIIGGRAAD RRTGAVRTFE YRPLHNNKRV NLIVTISGWL
TGKVDDVRLP FSTVDPVMGD LYSVLFEPEM LRSMGDTINI LATEALTQSI QQILGTTILA
ALMSALQLPI ILTKLAYLID NPWAVSLDRA TSAGKILADS LLERNLGTRP ITLVGFSIGA
RVVFSCLQEL SKKGAVGIVQ NVYMFGSPIV VKKEEYIKAK TVVSGRFLNA YNRNDWILGY
LFRLTSGGIR RVAGLAPVED CPFVENMDVT DLVNGHMDYR QKMPVLLIRC GWSVESEEFV
EIEDPDPDNH NERQRELINE IEEARKNLEK EGKAKKSGRF SFFGRRKNAE KQDWEIYEDS
KNKGEGKEKA KEGEQADNNT GVLFDIDAIR AEIAKDARDH YASPEDLQVK EIKSTLPPMK
LDVSSLPASP SAVANGSRAG SRTDLTGARD SHDTRVSQER SHSYTPSYTR QASPPGYSSP
YGGGFGSGHG DAYGSGRHDE DDIQMTFDTS FDDHPRSATV APTETAATRP QVKTAQTLPT
MTLHEPWGDS DDDDFGKEKE ISMTFA
//
