ID A0A2H3IKR9_9EURO Unreviewed; 410 AA.
AC A0A2H3IKR9;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=O-methyltransferase, family 2 {ECO:0000313|EMBL:PCH00246.1};
GN ORFNames=PENO1_048890 {ECO:0000313|EMBL:PCH00246.1};
OS Penicillium occitanis (nom. inval.).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=290292 {ECO:0000313|EMBL:PCH00246.1, ECO:0000313|Proteomes:UP000218381};
RN [1] {ECO:0000313|EMBL:PCH00246.1, ECO:0000313|Proteomes:UP000218381}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CL100 {ECO:0000313|EMBL:PCH00246.1,
RC ECO:0000313|Proteomes:UP000218381};
RX PubMed=28951729; DOI=10.3389/fmicb.2017.01627;
RA Bravo-Ruiz G., Sassi A.H., Marcet-Houben M., Di Pietro A., Gargouri A.,
RA Gabaldon T., Roncero M.I.G.;
RT "Regulatory Mechanisms of a Highly Pectinolytic Mutant of Penicillium
RT occitanis and Functional Analysis of a Candidate Gene in the Plant Pathogen
RT Fusarium oxysporum.";
RL Front. Microbiol. 8:1627-1627(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PCH00246.1}.
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DR EMBL; NPFK01000123; PCH00246.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2H3IKR9; -.
DR OrthoDB; 1067404at2759; -.
DR Proteomes; UP000218381; Unassembled WGS sequence.
DR GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0044550; P:secondary metabolite biosynthetic process; IEA:UniProt.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR016461; COMT-like.
DR InterPro; IPR001077; O_MeTrfase_dom.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR43712:SF11; O-METHYLTRANSFERASE (AFU_ORTHOLOGUE AFUA_2G17820)-RELATED; 1.
DR PANTHER; PTHR43712; PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED; 1.
DR Pfam; PF00891; Methyltransf_2; 1.
DR PIRSF; PIRSF005739; O-mtase; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51683; SAM_OMT_II; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:PCH00246.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000218381};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000313|EMBL:PCH00246.1}.
FT DOMAIN 227..386
FT /note="O-methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00891"
FT ACT_SITE 315
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR005739-1"
SQ SEQUENCE 410 AA; 45728 MW; 38F86B64A714BF42 CRC64;
MSSIEQLTVL LNEAAESLPA QGPINDEKRN AFYAAYENVR KAIETPIDAA VRVLFGGYDA
VALRVAMDTQ IFNQLATAGG QSKSISELAK PSGADPLLLN RFIRILAASG LVKETGEGEY
ASVPLTGAFS DMSPLSKSAF HISDKAQMRS LSNANSLAKL PQYLQKTNYQ NPNDSWDGPF
QFGEATNLQY FEWIEQDPKH QEAFNTHMTL QRMERGPNWF DFYPVQERLL DTDNDTSKKF
LVDLGGGVGH DLAAFTEKYP DLASRLVLED LGHVLADVDK QQFKLHPGIE RVPTDLFQEQ
TVKGAKVYYL RTVLHDWPDK QAKQILKNIH EAMTNDSVLI LNENALPDEN VGGFQARVDI
LMMSILSGID RTYKQFHKLL EESGFEVLGT YRPQTLSPGA GTIFEAVKKH
//
