ID   A0A2H3ISR0_9EURO        Unreviewed;       822 AA.
AC   A0A2H3ISR0;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   SubName: Full=Cullin homology {ECO:0000313|EMBL:PCH00940.1};
GN   ORFNames=PENO1_045530 {ECO:0000313|EMBL:PCH00940.1};
OS   Penicillium occitanis (nom. inval.).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX   NCBI_TaxID=290292 {ECO:0000313|EMBL:PCH00940.1, ECO:0000313|Proteomes:UP000218381};
RN   [1] {ECO:0000313|EMBL:PCH00940.1, ECO:0000313|Proteomes:UP000218381}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CL100 {ECO:0000313|EMBL:PCH00940.1,
RC   ECO:0000313|Proteomes:UP000218381};
RX   PubMed=28951729; DOI=10.3389/fmicb.2017.01627;
RA   Bravo-Ruiz G., Sassi A.H., Marcet-Houben M., Di Pietro A., Gargouri A.,
RA   Gabaldon T., Roncero M.I.G.;
RT   "Regulatory Mechanisms of a Highly Pectinolytic Mutant of Penicillium
RT   occitanis and Functional Analysis of a Candidate Gene in the Plant Pathogen
RT   Fusarium oxysporum.";
RL   Front. Microbiol. 8:1627-1627(2017).
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC       {ECO:0000256|ARBA:ARBA00004906}.
CC   -!- SIMILARITY: Belongs to the cullin family.
CC       {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC       ECO:0000256|RuleBase:RU003829}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PCH00940.1}.
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DR   EMBL; NPFK01000110; PCH00940.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2H3ISR0; -.
DR   STRING; 290292.A0A2H3ISR0; -.
DR   OrthoDB; 5474206at2759; -.
DR   Proteomes; UP000218381; Unassembled WGS sequence.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR045093; Cullin.
DR   InterPro; IPR016158; Cullin_homology.
DR   InterPro; IPR036317; Cullin_homology_sf.
DR   InterPro; IPR001373; Cullin_N.
DR   InterPro; IPR019559; Cullin_neddylation_domain.
DR   InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11932; CULLIN; 1.
DR   PANTHER; PTHR11932:SF168; CULLIN-3; 1.
DR   Pfam; PF00888; Cullin; 1.
DR   Pfam; PF10557; Cullin_Nedd8; 1.
DR   SMART; SM00182; CULLIN; 1.
DR   SMART; SM00884; Cullin_Nedd8; 1.
DR   SUPFAM; SSF75632; Cullin homology domain; 1.
DR   SUPFAM; SSF74788; Cullin repeat-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50069; CULLIN_2; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000218381}.
FT   DOMAIN          441..687
FT                   /note="Cullin family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50069"
FT   REGION          361..388
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          732..751
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   822 AA;  93974 MW;  2BFF64C67BDCA2F6 CRC64;
     MAMRARQKVR APRRALGSKN DDFEAIWSVL GSALREIHTK NASSLSFEEL YRSSYRIVLM
     GKGDELYERV KQLEQEWLSS LVSQNIMSSV SPVLLLNIEP TDTTDQANER RAAGERFLAA
     MRGAWEDHQL CMGMITDVLM YMDKVMNTDQ KPSIYTVSMC LFRDNVLRSA VPDSNLTIYK
     ILESTVLFMV QLERTGEMID RPLVRHCIYM LEGLYETLEE EESAKLYLSV FEPTYLQIST
     IFYQNEGKRL LETADAATFC RVSSERISEE EERCHATLSP YSEQKIKAVI DEQLISKNIT
     DVINLEGSGV RYMLDHDRVQ DLANVYELNA RIDPKKGALT KSIQTRIVQL GNEVNAAAKA
     FATAPPPAKS TEADGEKKSE KEKPVAPPVN QQTAAAIKWV DDILNLKKKF DAIWERAFAS
     DQGMHTSFTN SFSDFINSNN RSSEYLSLFF DENLKKGIKG KTDAEVDSLL ENGITLLRYI
     RDKDLFETYY KKHLSRRLLM KRSVSMDVER QMISKMKMEV GNQFTQRLEA MFKDMSVSED
     LTNNYKAHMS RTAANSKRFE LEISVLTSTM WPMEIMSSSK DGDMQLPCIF PKDVDAVRQS
     FEKFYLDKHS GRKLSWQASM GTADIRATFP RAEGKYARHD LNVSTYAMII LLLFNDLPLD
     ESLTYEEIQA RTRIPDHDLI RNLQSLAVAP KTRVLKKEPM SKDVKPTDRF FYNASFKSQF
     TKVRIGVVSS GGNKVENQNE RNETEKKMNE ERGGSIEAAV VRIMKQRKKL AHSQLLTEVL
     GQLAARFVPD VNMIKKRIES LIDREYLERI PDSDPPAYGY VA
//