ID A0A2H3JHK1_WOLCO Unreviewed; 1408 AA.
AC A0A2H3JHK1;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=DNA-directed RNA polymerase subunit {ECO:0000256|RuleBase:RU004279};
DE EC=2.7.7.6 {ECO:0000256|RuleBase:RU004279};
GN ORFNames=WOLCODRAFT_163287 {ECO:0000313|EMBL:PCH41652.1};
OS Wolfiporia cocos (strain MD-104) (Brown rot fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Phaeolaceae; Wolfiporia.
OX NCBI_TaxID=742152 {ECO:0000313|EMBL:PCH41652.1, ECO:0000313|Proteomes:UP000218811};
RN [1] {ECO:0000313|EMBL:PCH41652.1, ECO:0000313|Proteomes:UP000218811}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MD-104 {ECO:0000313|EMBL:PCH41652.1,
RC ECO:0000313|Proteomes:UP000218811};
RX PubMed=22745431; DOI=10.1126/science.1221748;
RA Floudas D., Binder M., Riley R., Barry K., Blanchette R.A., Henrissat B.,
RA Martinez A.T., Otillar R., Spatafora J.W., Yadav J.S., Aerts A., Benoit I.,
RA Boyd A., Carlson A., Copeland A., Coutinho P.M., de Vries R.P.,
RA Ferreira P., Findley K., Foster B., Gaskell J., Glotzer D., Gorecki P.,
RA Heitman J., Hesse C., Hori C., Igarashi K., Jurgens J.A., Kallen N.,
RA Kersten P., Kohler A., Kuees U., Kumar T.K.A., Kuo A., LaButti K.,
RA Larrondo L.F., Lindquist E., Ling A., Lombard V., Lucas S., Lundell T.,
RA Martin R., McLaughlin D.J., Morgenstern I., Morin E., Murat C., Nagy L.G.,
RA Nolan M., Ohm R.A., Patyshakuliyeva A., Rokas A., Ruiz-Duenas F.J.,
RA Sabat G., Salamov A., Samejima M., Schmutz J., Slot J.C., St John F.,
RA Stenlid J., Sun H., Sun S., Syed K., Tsang A., Wiebenga A., Young D.,
RA Pisabarro A., Eastwood D.C., Martin F., Cullen D., Grigoriev I.V.,
RA Hibbett D.S.;
RT "The Paleozoic origin of enzymatic lignin decomposition reconstructed from
RT 31 fungal genomes.";
RL Science 336:1715-1719(2012).
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000256|RuleBase:RU004279}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000256|ARBA:ARBA00024550,
CC ECO:0000256|RuleBase:RU004279};
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta' chain family.
CC {ECO:0000256|RuleBase:RU004279}.
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DR EMBL; KB468113; PCH41652.1; -; Genomic_DNA.
DR STRING; 742152.A0A2H3JHK1; -.
DR OMA; AVCPPYN; -.
DR OrthoDB; 169836at2759; -.
DR Proteomes; UP000218811; Unassembled WGS sequence.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR CDD; cd02736; RNAP_III_Rpc1_C; 1.
DR CDD; cd02583; RNAP_III_RPC1_N; 1.
DR Gene3D; 1.10.132.30; -; 1.
DR Gene3D; 1.10.150.390; -; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 6.10.250.2940; -; 1.
DR Gene3D; 6.20.50.80; -; 1.
DR Gene3D; 3.30.1490.180; RNA polymerase ii; 1.
DR Gene3D; 4.10.860.120; RNA polymerase II, clamp domain; 1.
DR Gene3D; 1.10.274.100; RNA polymerase Rpb1, domain 3; 1.
DR InterPro; IPR045867; DNA-dir_RpoC_beta_prime.
DR InterPro; IPR000722; RNA_pol_asu.
DR InterPro; IPR006592; RNA_pol_N.
DR InterPro; IPR007080; RNA_pol_Rpb1_1.
DR InterPro; IPR007066; RNA_pol_Rpb1_3.
DR InterPro; IPR042102; RNA_pol_Rpb1_3_sf.
DR InterPro; IPR007083; RNA_pol_Rpb1_4.
DR InterPro; IPR007081; RNA_pol_Rpb1_5.
DR InterPro; IPR044893; RNA_pol_Rpb1_clamp_domain.
DR InterPro; IPR035698; RNAP_III_Rpc1_C.
DR InterPro; IPR035697; RNAP_III_RPC1_N.
DR InterPro; IPR038120; Rpb1_funnel_sf.
DR PANTHER; PTHR19376; DNA-DIRECTED RNA POLYMERASE; 1.
DR PANTHER; PTHR19376:SF32; DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC1; 1.
DR Pfam; PF04997; RNA_pol_Rpb1_1; 1.
DR Pfam; PF00623; RNA_pol_Rpb1_2; 1.
DR Pfam; PF04983; RNA_pol_Rpb1_3; 1.
DR Pfam; PF05000; RNA_pol_Rpb1_4; 1.
DR Pfam; PF04998; RNA_pol_Rpb1_5; 1.
DR SMART; SM00663; RPOLA_N; 1.
DR SUPFAM; SSF64484; beta and beta-prime subunits of DNA dependent RNA-polymerase; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW ECO:0000256|RuleBase:RU004279};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW ECO:0000256|RuleBase:RU004279}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000218811};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU004279};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU004279}.
FT DOMAIN 244..546
FT /note="RNA polymerase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00663"
SQ SEQUENCE 1408 AA; 156781 MW; B3437AE305013322 CRC64;
MKESVSHQAP KVIKKLQFSL FTNQDAVKVS EFEVTHRDLY TAVDRHPVKN GVLDRRLGTT
EKSAFCETCG LSSVDCVGHY AYIKLAVPVF HIGYFKHTIS ILQCICKTCA RVLLEEPERR
TYLKRFRRPN LENIQRQALC KAVNTLARKM VYCPYCAATN GTVKKAGALK IIHDKFRAKK
TAEEMEKWKM TFAPAVEAQK ELGMYISKAV HEDLNPLKVL NLFKRISDED CELLGLRPTY
GRPEEYIWQY ISVPPVCIRP SVAQDGASNE DDLTVKLTEI VFTNALIKQG LAKGAPTAQF
MEQWDFLQIS VAMYINSELP GVPPQMGQKP IRGFCQRLKG KQGRFRGNLS GKRVDFSGRT
VISPDPNLRI DEVAVPERVA KILTYPERVT SHNIEMLKKA VRNGTDVHPG ANYVTAGSSG
FKKFLKFGHK EAIADSLRIG DIVERHIIDG DIVLFNRQPS LHKLSIMCHR VKVRPWRSFR
LNECVCGPYN ADFDGDEMNL HVPQTEEART EALELMSVKH NLVTPRNGEP VIAAIQDFIT
ASFLLSRKDR FFDRRQFTQI CSYFGDADLQ IDIPPPTIWK PVRLWTGKQI FNVLMRPNKT
YKVFVNVESK CNKQEKPDPK QYPRMNPALD LSPNDGWLVI VNSEIMCGVM DKATVGSGKK
KSVFGIIMRD YGPHEAAAAM NRLAKLCARW LANYGFSLGI NDVIPGPKLS LEKNNLVETA
YAECQDLIMR AKKGLLENKP GCDQEQTLEA MISGVLSKVR DKVGEICLKE LSRHNAPLIM
ATCGSKGSVI NVAQMVACVG QQIIAGHRVP DGFQDRSLPH FPKKSREPPS KGFVRNSFYT
GLSPTEFLFH AISGREGLVD TAVKTAETGY MQRRLMKALE DLVTHYDSSV RNAVGGVVQF
RYGDDGLDPA CLEGDAQPVE FLRAWSHASS IGSRHTRGLL PFEIMELVDS ELSQRKFTSE
CTAAYLATIR GFISEHVAQK LAGIRKNHGM FDAIERDDEW DAETDLTLGA SGKWLAYADK
AVVDNKLKVT EDQLRAFLEI CWTKYVKAKI EPGSTVGAVG AQSIGEPGTQ MTLKTFHFAG
VASMNVTLGV PRIKEIINAA KSISTPIISC KLVTADSEAS ARIVKGRLEK THLGDVAAVL
EEAWAPEYTY IGIIVDMKTI QDLQLELTLD DIKWGIVAAK KLKIKQESIT VIPRKNRLRV
YVDGPDKYYR LRELKRALPD VVVKGVSTIR RAIINIKTDD DHRGKKGDKE LLVEGYGLQK
VMVTQGIVGE QTTSNHIIEV AQVLGIEAAR RTIINEIQYT MASHGMSIDP RHVMLLGDVM
SYKGEVLGIT RFGVAKMKDS VLMLASFEKT TDHLFDASAY GKTDSIAGVS ESIIMGNPAA
MTGTSMPALV TPAPPIGKPR KLLFEGAL
//
