ID A0A2H3K3A6_WOLCO Unreviewed; 883 AA.
AC A0A2H3K3A6;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=DUF1793-domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=WOLCODRAFT_164515 {ECO:0000313|EMBL:PCH43524.1};
OS Wolfiporia cocos (strain MD-104) (Brown rot fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Phaeolaceae; Wolfiporia.
OX NCBI_TaxID=742152 {ECO:0000313|EMBL:PCH43524.1, ECO:0000313|Proteomes:UP000218811};
RN [1] {ECO:0000313|EMBL:PCH43524.1, ECO:0000313|Proteomes:UP000218811}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MD-104 {ECO:0000313|EMBL:PCH43524.1,
RC ECO:0000313|Proteomes:UP000218811};
RX PubMed=22745431; DOI=10.1126/science.1221748;
RA Floudas D., Binder M., Riley R., Barry K., Blanchette R.A., Henrissat B.,
RA Martinez A.T., Otillar R., Spatafora J.W., Yadav J.S., Aerts A., Benoit I.,
RA Boyd A., Carlson A., Copeland A., Coutinho P.M., de Vries R.P.,
RA Ferreira P., Findley K., Foster B., Gaskell J., Glotzer D., Gorecki P.,
RA Heitman J., Hesse C., Hori C., Igarashi K., Jurgens J.A., Kallen N.,
RA Kersten P., Kohler A., Kuees U., Kumar T.K.A., Kuo A., LaButti K.,
RA Larrondo L.F., Lindquist E., Ling A., Lombard V., Lucas S., Lundell T.,
RA Martin R., McLaughlin D.J., Morgenstern I., Morin E., Murat C., Nagy L.G.,
RA Nolan M., Ohm R.A., Patyshakuliyeva A., Rokas A., Ruiz-Duenas F.J.,
RA Sabat G., Salamov A., Samejima M., Schmutz J., Slot J.C., St John F.,
RA Stenlid J., Sun H., Sun S., Syed K., Tsang A., Wiebenga A., Young D.,
RA Pisabarro A., Eastwood D.C., Martin F., Cullen D., Grigoriev I.V.,
RA Hibbett D.S.;
RT "The Paleozoic origin of enzymatic lignin decomposition reconstructed from
RT 31 fungal genomes.";
RL Science 336:1715-1719(2012).
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DR EMBL; KB468146; PCH43524.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2H3K3A6; -.
DR STRING; 742152.A0A2H3K3A6; -.
DR OMA; SPYLSCW; -.
DR OrthoDB; 1658223at2759; -.
DR Proteomes; UP000218811; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 1.20.5.510; Single helix bin; 1.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR014870; GtaA_C.
DR InterPro; IPR032514; GtaA_central.
DR InterPro; IPR033433; GtaA_N.
DR PANTHER; PTHR31987:SF1; GLUTAMINASE A; 1.
DR PANTHER; PTHR31987; GLUTAMINASE A-RELATED; 1.
DR Pfam; PF08760; DUF1793; 1.
DR Pfam; PF16335; DUF4965; 1.
DR Pfam; PF17168; DUF5127; 1.
DR SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000218811};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..883
FT /note="DUF1793-domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5013897642"
FT TRANSMEM 720..744
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 108..341
FT /note="Glutaminase A N-terminal"
FT /evidence="ECO:0000259|Pfam:PF17168"
FT DOMAIN 347..513
FT /note="Glutaminase A central"
FT /evidence="ECO:0000259|Pfam:PF16335"
FT DOMAIN 521..695
FT /note="Glutaminase A C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08760"
FT REGION 812..855
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 883 AA; 96731 MW; 45D2927CCD69FD62 CRC64;
MLSSLLLSLT ILLRINVVQS QNTESPLGSA YLPLAVRSPY LSCWLNPTPN LTYHWPNFPQ
SPSQYLGWEG HIRVDNITYA WLGSLAESSN GPPNLRQVEF LSTEITPTRT IQHLQAGAMD
ITVTYMSPIE PLDWSKQSMP FSYMAVNASS SDGQAHEVQL YSDISAEWVS GDRGATVNWT
LSATNQPYVY HKIQLVNPEP FQENAGQASD GVAYYAMALE QGVNVTYQAC QDVRCRAQFT
DYGYLNKTQN TTFRPISSDF PVFAFAVDLG YMETTNSPVV WSVGYVRNPS INYEISQYKS
TYRSLFFWSQ YQTIDEVISE FLTDYGDALS RAVAFDNTIQ QAAASYSSEY SSVVSFAARQ
VFGALDITLP QPSSGGTWDT SDVKIFMKNI GNDGRVNPVE KIYAALPMFL YINASYVEYL
LAPLFELQNT STYPYSFAAR DLGTAYPNAS LTSASAESQE GVEQTGNMLI MTYAHALYTG
NGNLISANYD LLKRWAEYLV NHTLYPSNPA NSTNLSVKGI IALNAMSRMS AAMHQGNDYE
RYAKVSSNLI EQWQSAAMAS DHSHLVADYG DSSESWALMY NLYPDRLLST SLLNQSIYDL
QQQYYSNLIQ SGSGYDYGLP ISSGAGPVGN SAWLSFTAAT VENTTLRDQF LSMVWKHATS
NVTGAIFPSV YYLNNGTPIS GSANPAQGAV FAPLALSLPS SSISVASDPF TTTSKAKSNL
SAIIGGVVGG AAAVLIVASA AVIYRRRYGK GKQQDLGLIA DASNVLSLEP FPYIAANNEP
DLSHPNALPT APTPQGHVLP RKASQALHMR NLDNQLPPGY TGSIAPPPET RGSAEPDPIY
PPAEIGEDPR EQELNGLRAE MQEMRRAMEE VYADQMEAPP SYS
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