ID A0A2H3NM87_9BACT Unreviewed; 834 AA.
AC A0A2H3NM87;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Cation/H(+) antiporter {ECO:0000313|EMBL:PEN05746.1};
GN ORFNames=CRI93_11615 {ECO:0000313|EMBL:PEN05746.1};
OS Longimonas halophila.
OC Bacteria; Rhodothermota; Rhodothermia; Rhodothermales; Salisaetaceae;
OC Longimonas.
OX NCBI_TaxID=1469170 {ECO:0000313|EMBL:PEN05746.1, ECO:0000313|Proteomes:UP000221024};
RN [1] {ECO:0000313|EMBL:PEN05746.1, ECO:0000313|Proteomes:UP000221024}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KCTC 42399 {ECO:0000313|EMBL:PEN05746.1,
RC ECO:0000313|Proteomes:UP000221024};
RA Goh K.M., Shamsir M.S., Lim S.W.;
RT "Draft genome of Longimonas halophila.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PEN05746.1}.
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DR EMBL; PDEP01000011; PEN05746.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2H3NM87; -.
DR OrthoDB; 9793589at2; -.
DR Proteomes; UP000221024; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR InterPro; IPR016152; PTrfase/Anion_transptr.
DR InterPro; IPR002178; PTS_EIIA_type-2_dom.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR006016; UspA.
DR PANTHER; PTHR43562:SF4; NA(+)_H(+) ANTIPORTER NHAS5; 1.
DR PANTHER; PTHR43562; NAPA-TYPE SODIUM/HYDROGEN ANTIPORTER; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
DR Pfam; PF00582; Usp; 1.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
DR SUPFAM; SSF55804; Phoshotransferase/anion transport protein; 1.
DR PROSITE; PS51094; PTS_EIIA_TYPE_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000221024};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 34..53
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 59..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..111
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 117..137
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 149..174
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 180..204
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 216..232
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 268..286
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 298..319
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 331..354
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 360..380
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 684..827
FT /note="PTS EIIA type-2"
FT /evidence="ECO:0000259|PROSITE:PS51094"
SQ SEQUENCE 834 AA; 90448 MW; FFD99BDEC4A5D0AD CRC64;
MIALPITNPV LIFATVMLIV LLAPMLFRRL GVPGLVGLIV AGAVVGPNAI GLLERGDTFE
LLGTVGLLYL MFTAGLSMDL NQFAQQKGRS FVFGFISFLM PQLLALGAGH YLMEWDLMTS
LLVGAVVGSH TLLAYPIAER LGITKNPSVT MTMGGTMVTD LVSLLILAIV SALVSGESGL
FFWIQFVVLV SGYGVVIFFA LPRLGRAFFQ GSDRQADMEF VFLLAVVFVA AYTAELVYLA
PIIGAFMTGI ALNRLVPERS ALMLRIKFVG DALFIPFFLI SVGMLVDASV LVQGLEVWLL
AGLLTAMVWG GKFIAAQAVQ WIYRYSSTER WVIFGLSTPQ AAATLAVTLI GFEMGLFSEA
LVNAVILLIL ATSILGPSLV EKYGRELALQ AERAAYNPTD VPQRIMVPLA NPESANDLMD
VAVLLRADAS EEAIYPTTVV RDGPNVEGDV AHGESMLSKA VLHAAASEVP VMPSTRIDYN
VVNGMVRAIK EDRISTVVIG WHGQSTAREY IFGSVLDQLL ERTRQMIIVS RFAHPMNTHT
RMVLAVPPYA DRESGFADAM RALKVLCNQA GLDLIVVAAE ASIEPLSRRI DATKPSVPWA
TQSMEQWGQL VHTLDDLVEP NDLLVLMNER EGSIAWRPGL DRLPGVIAQR FADHTFLTVY
MSEERFAPAP SSRPDRIDSG VLSEALRPEC VVMGMPDVDT DDMLRHVMRC ALGDRPDIIE
AVLPGLLDAE GYAPELRPGV ALYAAHTRHA EQSSLLVGIS ADGVRPKHTS GPVHVVLVLL
VPRTVPTDWY LQHLAAAAEL IQTNEAVESL RTAETAKTAR KRLLEEATTA SAVA
//
