ID   A0A2H3SU48_FUSOX        Unreviewed;       983 AA.
AC   A0A2H3SU48;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Probable mitotic control protein dis3 {ECO:0000313|EMBL:SCO79932.1};
GN   ORFNames=FRV6_04145 {ECO:0000313|EMBL:SCO79932.1};
OS   Fusarium oxysporum (Fusarium vascular wilt).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC   Fusarium oxysporum species complex.
OX   NCBI_TaxID=5507 {ECO:0000313|EMBL:SCO79932.1, ECO:0000313|Proteomes:UP000219369};
RN   [1] {ECO:0000313|Proteomes:UP000219369}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=V64-1 {ECO:0000313|Proteomes:UP000219369};
RA   Guldener U.;
RL   Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the RNR ribonuclease family.
CC       {ECO:0000256|ARBA:ARBA00005785, ECO:0000256|RuleBase:RU003901}.
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DR   EMBL; FMJY01000002; SCO79932.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2H3SU48; -.
DR   VEuPathDB; FungiDB:FOC1_g10015489; -.
DR   VEuPathDB; FungiDB:FOC4_g10015376; -.
DR   VEuPathDB; FungiDB:FOIG_00677; -.
DR   VEuPathDB; FungiDB:FOMG_00866; -.
DR   VEuPathDB; FungiDB:FOXG_00205; -.
DR   VEuPathDB; FungiDB:FOZG_00864; -.
DR   VEuPathDB; FungiDB:HZS61_000616; -.
DR   OrthoDB; 945235at2759; -.
DR   Proteomes; UP000219369; Unassembled WGS sequence.
DR   GO; GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004540; F:RNA nuclease activity; IEA:InterPro.
DR   CDD; cd09862; PIN_Rrp44-like; 1.
DR   Gene3D; 2.40.50.690; -; 1.
DR   Gene3D; 2.40.50.700; -; 1.
DR   Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR   Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR   InterPro; IPR041505; Dis3_CSD2.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR029060; PIN-like_dom_sf.
DR   InterPro; IPR002716; PIN_dom.
DR   InterPro; IPR001900; RNase_II/R.
DR   InterPro; IPR022966; RNase_II/R_CS.
DR   InterPro; IPR033771; Rrp44_CSD1.
DR   InterPro; IPR033770; RRP44_S1.
DR   PANTHER; PTHR23355:SF35; EXOSOME COMPLEX EXONUCLEASE RRP44; 1.
DR   PANTHER; PTHR23355; RIBONUCLEASE; 1.
DR   Pfam; PF17849; OB_Dis3; 1.
DR   Pfam; PF13638; PIN_4; 1.
DR   Pfam; PF00773; RNB; 1.
DR   Pfam; PF17216; Rrp44_CSD1; 1.
DR   Pfam; PF17215; Rrp44_S1; 1.
DR   SMART; SM00670; PINc; 1.
DR   SMART; SM00955; RNB; 1.
DR   SUPFAM; SSF50249; Nucleic acid-binding proteins; 4.
DR   SUPFAM; SSF88723; PIN domain-like; 1.
DR   PROSITE; PS01175; RIBONUCLEASE_II; 1.
PE   3: Inferred from homology;
KW   Exosome {ECO:0000256|ARBA:ARBA00022835};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT   DOMAIN          85..204
FT                   /note="PIN"
FT                   /evidence="ECO:0000259|SMART:SM00670"
FT   DOMAIN          514..847
FT                   /note="Ribonuclease II/R"
FT                   /evidence="ECO:0000259|SMART:SM00955"
SQ   SEQUENCE   983 AA;  111402 MW;  F03C16287B1E8B28 CRC64;
     MASLKRSTET DSLASNISSK VYVRSTRSGK VQKIVREVYL RTDIPCSSKL CKACLQDAPR
     NAAQQAQPFV LSDKPAGTET FPQGHYLVPD TNALLNAMDL FEQSSAFYDV IILQTVLEEL
     RNRSLPLYNR LVGLTKSEDK RFYVFFNDFR LETFVHRQAN ETVNDRNDRA VRLAVKWYGE
     HLARTKAKKL PAVVMLSDDR ENLRKAKEEG LHASSLRDYV SGLEDGERLL DMVAEAQNQE
     SFKKQGQMLY PEYFTLSRMM TGVKAGLMHQ GIFNVSPYNY LEGSIKVPAF PKPLLVLGRE
     NINRAVDGDV VVVEVLPQDQ WKEPSTKIIE EDAITKNENA DVEESQDLVS EKERKALQEQ
     VRKTQKSASE SKPQPTAKVV GVIKRNWRQY VGHIDPSSAS KGSSQGRKQD SVFLIPMDKK
     IPKIRLRTRQ VADLLGKRLL VTIDAWERDS RHPVGHFVRS LGELETKSAE TEALLLEWDV
     QYRPFPKTVL DCLPREGHDW RVPTSMEDPG WRQREDLRGL LICSIDPVGC QDIDDALHAK
     QLPNGNYEVG VHIADVSNFV KPANAMDAEA SIRGTTVYLV DKRIDMLPPL LGTDLCSLKP
     YVERFAFSVL WELNDNADIV NVRFTKSVIK SREAFSYEQA QLRIDDESQQ DDLTKGMRML
     LMLSKKLKKK RMDAGALSLS SPEVKVQTES ETSDPIDVKT KQLLDTNSLV EEFMLFANVS
     VAAKIYEAFP QTAILRRHAA PPKTNFDELS NQLRTKRGME LRTDSSKALA DSLDQCVDPK
     EPFFNTLVRI MATRCMMSAE YFCSGTQAYP EFRHYGLASE IYTHFTSPIR RYADLLAHRQ
     LAAAIDYEAI HPNVRSRGRL EAVCKNINVR HRNAQMAGRA SIAYYVGQAL KGKVAEEDAF
     VMKIFSNGFV VLVPRFGTEG LIRLRDLAEP EPEAEYDAET YTLTTKGSCE IKVELFQKVR
     VRVRDEKDEM TGKRGVKMEL IEA
//