ID   A0A2H3SZ17_FUSOX        Unreviewed;       372 AA.
AC   A0A2H3SZ17;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   24-JAN-2024, entry version 13.
DE   RecName: Full=Enoyl reductase (ER) domain-containing protein {ECO:0000259|SMART:SM00829};
GN   ORFNames=FRV6_00042 {ECO:0000313|EMBL:SCO75830.1};
OS   Fusarium oxysporum (Fusarium vascular wilt).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC   Fusarium oxysporum species complex.
OX   NCBI_TaxID=5507 {ECO:0000313|EMBL:SCO75830.1, ECO:0000313|Proteomes:UP000219369};
RN   [1] {ECO:0000313|Proteomes:UP000219369}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=V64-1 {ECO:0000313|Proteomes:UP000219369};
RA   Guldener U.;
RL   Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family. {ECO:0000256|ARBA:ARBA00008072}.
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DR   EMBL; FMJY01000001; SCO75830.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2H3SZ17; -.
DR   VEuPathDB; FungiDB:FOC1_g10000724; -.
DR   VEuPathDB; FungiDB:FOC4_g10011103; -.
DR   VEuPathDB; FungiDB:FOIG_15870; -.
DR   VEuPathDB; FungiDB:FOMG_05554; -.
DR   VEuPathDB; FungiDB:FOXG_01587; -.
DR   VEuPathDB; FungiDB:FOZG_17390; -.
DR   VEuPathDB; FungiDB:HZS61_004354; -.
DR   OrthoDB; 2093633at2759; -.
DR   Proteomes; UP000219369; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   PANTHER; PTHR42940; ALCOHOL DEHYDROGENASE 1-RELATED; 1.
DR   PANTHER; PTHR42940:SF8; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   NADP {ECO:0000256|ARBA:ARBA00022857}.
FT   DOMAIN          14..364
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   372 AA;  40287 MW;  27E3005A4F634968 CRC64;
     MSQTQTAAVV EKFGKPYTFK QVSRPKDPED QDILIKVLAA SYCHTDAVFA AGLLSQDLPR
     IGCHEFAGEV IALGPNVSSR RGVAVGTRVG VPGRAYHPCG TCFECTHPGQ DDMGYSPYCP
     RSGNLGLTRD GGFQEYCLVD SRQVAVLPKT LPPTQAAPLM CAGLTIWSAL QHEKVHRAQR
     VGIIGAGGGL GHIGVQFAAH LGKDVLAVDA TDQAINLIHK VKANLGEAGK KVYISDARNE
     DSNELREMIQ PASDAPPTEI GLDTVILLPE SQRAFDAGMK LLRNHGTMVV VSFPNDKLQV
     SAHDLVFRDI EVVGSLVGRN QQLREMLEFV VKKQVQVQVK TFAFDRLNEL RGPEHHAEGG
     KLVIDMALDR AV
//