ID A0A2H3T253_FUSOX Unreviewed; 540 AA.
AC A0A2H3T253;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=Phosphotransferase {ECO:0000256|RuleBase:RU362007};
DE EC=2.7.1.- {ECO:0000256|RuleBase:RU362007};
GN ORFNames=FRV6_06920 {ECO:0000313|EMBL:SCO82707.1};
OS Fusarium oxysporum (Fusarium vascular wilt).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=5507 {ECO:0000313|EMBL:SCO82707.1, ECO:0000313|Proteomes:UP000219369};
RN [1] {ECO:0000313|Proteomes:UP000219369}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=V64-1 {ECO:0000313|Proteomes:UP000219369};
RA Guldener U.;
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the hexokinase family.
CC {ECO:0000256|ARBA:ARBA00009225, ECO:0000256|RuleBase:RU362007}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FMJY01000004; SCO82707.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2H3T253; -.
DR VEuPathDB; FungiDB:FOC1_g10004564; -.
DR VEuPathDB; FungiDB:FOC4_g10001712; -.
DR VEuPathDB; FungiDB:FOIG_15525; -.
DR VEuPathDB; FungiDB:FOMG_16176; -.
DR VEuPathDB; FungiDB:FOXG_02600; -.
DR VEuPathDB; FungiDB:FOZG_04550; -.
DR VEuPathDB; FungiDB:HZS61_010466; -.
DR OrthoDB; 5481886at2759; -.
DR UniPathway; UPA00109; UER00180.
DR Proteomes; UP000219369; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0005536; F:glucose binding; IEA:InterPro.
DR GO; GO:0004396; F:hexokinase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0001678; P:intracellular glucose homeostasis; IEA:InterPro.
DR CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR Gene3D; 1.10.287.1250; -; 1.
DR Gene3D; 3.30.420.40; -; 1.
DR Gene3D; 3.40.367.20; -; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR001312; Hexokinase.
DR InterPro; IPR022673; Hexokinase_C.
DR InterPro; IPR022672; Hexokinase_N.
DR PANTHER; PTHR19443:SF30; GLUCOKINASE-1-RELATED; 1.
DR PANTHER; PTHR19443; HEXOKINASE; 1.
DR Pfam; PF00349; Hexokinase_1; 1.
DR Pfam; PF03727; Hexokinase_2; 2.
DR PRINTS; PR00475; HEXOKINASE.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR PROSITE; PS51748; HEXOKINASE_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU362007};
KW Glycolysis {ECO:0000256|RuleBase:RU362007};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000256|RuleBase:RU362007};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU362007};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU362007}.
FT DOMAIN 14..210
FT /note="Hexokinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00349"
FT DOMAIN 221..410
FT /note="Hexokinase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03727"
FT DOMAIN 479..537
FT /note="Hexokinase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03727"
SQ SEQUENCE 540 AA; 58740 MW; B2E0542D1F41A239 CRC64;
MLEDGLGDSQ QATVQSVAQE FEVGNEKIQE ITNYFVKQIK HGLKDKHAYQ IPSFVTQIPS
GREKGLFLAV DLGGTNCRVC AVTLHGDSTF DVLQRKHLVP HDIRVHSSHK PLFHFIALKI
QDLLREHKSS GSSDSSEACF NLGFTFSFTC EQTSISSGTL VHWDKGWDIP STLGQDPCAL
LQEAIDEISL PVRVRVLAND AVGTLLTRAY TSKTKNSTLA SIILGTGTNA AYIERMSNIQ
RLDTTADRAH HSNSDGFMVI NTEWGSWDDG LKVLPQTRFD KLVDESSSDP GCGLLEKMVS
GMYLGELLRL SLLDLMRHGA LDMSFPDGSP VYIHMGIESA FLSKIAESKP ENSLSALSCI
TDTLVATGVT SRDLRTIQML ATVIVKRSAR LVGAGLAAIL IQSGRLDTSG MSQKTGLGAH
THQIQDKSTS TQIGSRRNTL TRFIRRMFGC IRPEEPSPIS TNGSSYDSKD TLESSELADE
VIDIAVDGSL FEFHTAFESF MRTALRDVEA IGKANEARIK IELTRDGSGT GAALIAAAAA
//
