ID   A0A2H3T636_FUSOX        Unreviewed;       493 AA.
AC   A0A2H3T636;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Related to pentafunctional arom polypeptide {ECO:0000313|EMBL:SCO84173.1};
GN   ORFNames=FRV6_08300 {ECO:0000313|EMBL:SCO84173.1};
OS   Fusarium oxysporum (Fusarium vascular wilt).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC   Fusarium oxysporum species complex.
OX   NCBI_TaxID=5507 {ECO:0000313|EMBL:SCO84173.1, ECO:0000313|Proteomes:UP000219369};
RN   [1] {ECO:0000313|Proteomes:UP000219369}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=V64-1 {ECO:0000313|Proteomes:UP000219369};
RA   Guldener U.;
RL   Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=NAD(+); Xref=ChEBI:CHEBI:57540;
CC         Evidence={ECO:0000256|ARBA:ARBA00001911};
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DR   EMBL; FMJY01000004; SCO84173.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2H3T636; -.
DR   VEuPathDB; FungiDB:FOC1_g10007978; -.
DR   VEuPathDB; FungiDB:FOC4_g10004309; -.
DR   VEuPathDB; FungiDB:FOIG_02508; -.
DR   VEuPathDB; FungiDB:FOMG_05909; -.
DR   VEuPathDB; FungiDB:FOXG_15363; -.
DR   VEuPathDB; FungiDB:FOZG_06058; -.
DR   VEuPathDB; FungiDB:HZS61_009223; -.
DR   OrthoDB; 453at2759; -.
DR   Proteomes; UP000219369; Unassembled WGS sequence.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0017000; P:antibiotic biosynthetic process; IEA:InterPro.
DR   CDD; cd08199; EEVS; 1.
DR   Gene3D; 3.40.50.1970; -; 1.
DR   Gene3D; 1.20.1090.10; Dehydroquinate synthase-like - alpha domain; 1.
DR   InterPro; IPR030960; DHQS/DOIS.
DR   InterPro; IPR035872; EEVS-like.
DR   PANTHER; PTHR43622; 3-DEHYDROQUINATE SYNTHASE; 1.
DR   PANTHER; PTHR43622:SF1; 3-DEHYDROQUINATE SYNTHASE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF01761; DHQ_synthase; 1.
DR   SUPFAM; SSF56796; Dehydroquinate synthase-like; 1.
PE   4: Predicted;
KW   Lyase {ECO:0000256|ARBA:ARBA00023239}; NAD {ECO:0000256|ARBA:ARBA00023027}.
FT   DOMAIN          86..335
FT                   /note="3-dehydroquinate synthase"
FT                   /evidence="ECO:0000259|Pfam:PF01761"
FT   REGION          432..470
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        442..466
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   493 AA;  54274 MW;  24539945F47700F5 CRC64;
     MSDMSATVEP TTKGFAVCGY EKIEYDFEFL DGVFNTANPQ LYQLYSPWGR CLAVMDLNIF
     NLYGNEMQRY FDHYGIPLTI HKTMIGEKAK SMDTLLSIVD SMTDFGIYRK EPVLVVGGGL
     VTDVAGFACA AYRRNTNYIR IPTTVIGLID ASVSIKVAVN YGRYKNRLGA YHAPSHTFLD
     FTFLRSLPVA QIRNGFAELI KISTCAHKDT YDLLEKYCEQ LINTGFGRSD DASPEIKEVA
     DKICRAGIHE MLKLETPNLH EIMLDRVIAY GHTWSPLHEL VPETPLRHGH AISIDMAYSA
     TLAHIRGLLS SEEHTRLLNL FSRAGLSMDH PQFDAPLLEK ATAAILKTRD GKLRAAVPVN
     PMGDCVFLND VSHDEMVAAL EEHKKIMKSY PRQGAGLEAF VDSSDTGYTM NGAPVENGNG
     QNIPLNGVEN AKLHASGPEG VDGLQQDSSS DDDYVVSSSK TNGHQGKGIL SDLKEKANGL
     QTQIAKAVTV ESQ
//