ID A0A2H3T6R6_FUSOX Unreviewed; 460 AA.
AC A0A2H3T6R6;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Related to delta-12 fatty acid desaturase {ECO:0000313|EMBL:SCO84418.1};
GN ORFNames=FRV6_08545 {ECO:0000313|EMBL:SCO84418.1};
OS Fusarium oxysporum (Fusarium vascular wilt).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=5507 {ECO:0000313|EMBL:SCO84418.1, ECO:0000313|Proteomes:UP000219369};
RN [1] {ECO:0000313|Proteomes:UP000219369}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=V64-1 {ECO:0000313|Proteomes:UP000219369};
RA Guldener U.;
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC -!- SIMILARITY: Belongs to the fatty acid desaturase type 1 family.
CC {ECO:0000256|ARBA:ARBA00009295}.
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DR EMBL; FMJY01000004; SCO84418.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2H3T6R6; -.
DR VEuPathDB; FungiDB:FOC1_g10002176; -.
DR VEuPathDB; FungiDB:FOC4_g10012263; -.
DR VEuPathDB; FungiDB:FOIG_12438; -.
DR VEuPathDB; FungiDB:FOMG_16960; -.
DR VEuPathDB; FungiDB:FOXG_08835; -.
DR VEuPathDB; FungiDB:FOZG_18523; -.
DR VEuPathDB; FungiDB:HZS61_004389; -.
DR OrthoDB; 4215at2759; -.
DR Proteomes; UP000219369; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016717; F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water; IEA:InterPro.
DR GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProt.
DR CDD; cd03507; Delta12-FADS-like; 1.
DR InterPro; IPR005804; FA_desaturase_dom.
DR InterPro; IPR021863; FAS_N.
DR InterPro; IPR012171; Fatty_acid_desaturase.
DR PANTHER; PTHR32100:SF35; OMEGA-3 FATTY ACID DESATURASE FAT-1; 1.
DR PANTHER; PTHR32100; OMEGA-6 FATTY ACID DESATURASE, CHLOROPLASTIC; 1.
DR Pfam; PF11960; DUF3474; 1.
DR Pfam; PF00487; FA_desaturase; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 81..103
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 115..136
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 281..303
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 309..329
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 56..92
FT /note="Fatty acid desaturase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF11960"
FT DOMAIN 118..404
FT /note="Fatty acid desaturase"
FT /evidence="ECO:0000259|Pfam:PF00487"
SQ SEQUENCE 460 AA; 51837 MW; E590618E7E0B0DB6 CRC64;
MASVSTSTVP GQHPAFRHTV TDFESSTSLS SLSSVDANRA KPTHDRLLDT YGNEFTPPDF
TIKDIRDAIP KHCFERSTFK GYIYILRDII CLVTTFTIFY NFVTPEYFPS TPVRALLWGL
YTTLQGLFGT GLWVIAHECG HQAFSESRLV NDATGWVLHS ALLVPYFSWQ ISHGKHHKAT
GNMDRDMVFV PRTPEQHATR IGRIAYELSE LTEETPAYTL LRLVMKQLVG WPSYILTNVT
GHNYHECQGE GRGKGKKNGL GGGVNHFDPR SPIYEAKQAK LIILSDIGIG IAIAALVYLS
NTFGWTNMLV WYGIPYLWVN HWLVAITFLQ HTDPTLPHYT ADEWNFVRGA AATIDRDMGF
IGRHLLHGII ETHVLHHYVS TIPFYNADEA SKAIRPVMGD HYRTDTKDGA WGFIRALWIS
AQMCQWVEPS AEAEGASKGI LFFRNHNGLS TKPVVLRKPE
//
