ID A0A2H3TC30_FUSOX Unreviewed; 891 AA.
AC A0A2H3TC30;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Related to alpha-actinin {ECO:0000313|EMBL:SCO83205.1};
GN ORFNames=FRV6_07418 {ECO:0000313|EMBL:SCO83205.1};
OS Fusarium oxysporum (Fusarium vascular wilt).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=5507 {ECO:0000313|EMBL:SCO83205.1, ECO:0000313|Proteomes:UP000219369};
RN [1] {ECO:0000313|Proteomes:UP000219369}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=V64-1 {ECO:0000313|Proteomes:UP000219369};
RA Guldener U.;
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the alpha-actinin family.
CC {ECO:0000256|ARBA:ARBA00010255}.
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DR EMBL; FMJY01000004; SCO83205.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2H3TC30; -.
DR VEuPathDB; FungiDB:FOC1_g10013627; -.
DR VEuPathDB; FungiDB:FOC4_g10010466; -.
DR VEuPathDB; FungiDB:FOIG_05672; -.
DR VEuPathDB; FungiDB:FOMG_04930; -.
DR VEuPathDB; FungiDB:FOXG_02131; -.
DR VEuPathDB; FungiDB:FOZG_05102; -.
DR VEuPathDB; FungiDB:HZS61_010032; -.
DR OrthoDB; 2872403at2759; -.
DR Proteomes; UP000219369; Unassembled WGS sequence.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR CDD; cd21215; CH_SpAIN1-like_rpt1; 1.
DR CDD; cd21291; CH_SpAIN1-like_rpt2; 1.
DR CDD; cd00051; EFh; 1.
DR Gene3D; 1.20.58.60; -; 2.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR Gene3D; 1.10.238.10; EF-hand; 2.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR014837; EF-hand_Ca_insen.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR PANTHER; PTHR11915:SF435; SPECTRIN BETA CHAIN, NON-ERYTHROCYTIC 5; 1.
DR PANTHER; PTHR11915; SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN; 1.
DR Pfam; PF00307; CH; 2.
DR Pfam; PF08726; EFhand_Ca_insen; 1.
DR SMART; SM00033; CH; 2.
DR SMART; SM01184; efhand_Ca_insen; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF46966; Spectrin repeat; 2.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS00020; ACTININ_2; 1.
DR PROSITE; PS50021; CH; 2.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 247..352
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 361..467
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 721..756
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 157..189
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 861..891
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 157..172
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 891 AA; 101296 MW; 9166DD20078CDA36 CRC64;
MDATKDSAQA FQGMLPLRPG NVEGNEKFPN FCLHADAQSS DDCDCNQQQR YQENKEDYYV
YQTDLSINNN SNQHHQHFHN SPSASISASS RLSYISTVSA SASSSSSRIS TASFESLPIT
PISVFEASPH SPRSLSNRLS SPVTGFIARR RTFTQDSCSL SYSPPSSPTP RTRRDKSQLH
AARVQRSGSR TTNTTFLLGL QIGKQSTNSR RFPPSASTPA DALAAVEPPH DQKLTRMAFA
EQQRWVTVQQ KTFTKWLNTK IEARNLEVKD LVKDLSDGVM LIHLLECLSH ESLGRYASKP
KLRVQKFENA NLALDFVKSR GIQMTNIGAE DVVDGNQKIV LGLIWTLILR FTISDINEEG
MSAKEGLLLW CQRKTACYDE VEVRDFSASW NDGLAFCALL DIHRPDLIDY DALDKKDHRG
NMQLAFDIAH KEIGIPKLLD VEDVCDVAKP DERSLMTYIA YWFHAFSQME KVENAGRRVE
KFVNNMQGAW EMQSAYERRM RALLQAIQEQ IEVWKQATFE GTYADAKAQS NQFFEYKKGK
KRQWVAEKSD LATLLGNIKT KLGTYRLRPY DPPAELSLDA LERKWAELAS NEMTRAQLIN
ETIRDIKNAL RKSFADKAND FAMALNTMQL AISGLDGDVE DQLHHVRKLS ESLSPLDQYL
DKISELDQKC QEANIEENDF TTYTYDELSY ELGLVKTSVQ KKLAFLENQM VARSMTNLTP
IQLEEFESVF RHFDRDDTNS LQELEFSAAL ASLGLVFSED EMHDYFLETS GGRDYVTFEQ
FIRFMVDVTE DQNTAEQVFQ SFREVADGKP YVTEMDLRHS LVPDEVIDQL IEIMPPHSGP
DMSEDRGMPQ YDYISFMEKL INDQNNQQEN PEATQQNRSD AEPQSPHTNG V
//
