ID A0A2H3THM0_FUSOX Unreviewed; 388 AA.
AC A0A2H3THM0;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Related to GLY1-L-threonine aldolase, low-specific {ECO:0000313|EMBL:SCO85241.1};
GN ORFNames=BFJ69_g5005 {ECO:0000313|EMBL:RKK79273.1}, FOXYS1_9515
GN {ECO:0000313|EMBL:KAF5259856.1}, FRV6_09368
GN {ECO:0000313|EMBL:SCO85241.1};
OS Fusarium oxysporum (Fusarium vascular wilt).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=5507 {ECO:0000313|EMBL:SCO85241.1, ECO:0000313|Proteomes:UP000219369};
RN [1] {ECO:0000313|EMBL:SCO85241.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=V64-1 {ECO:0000313|EMBL:SCO85241.1};
RA Capua I., De Benedictis P., Joannis T., Lombin L.H., Cattoli G.;
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000219369}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=V64-1 {ECO:0000313|Proteomes:UP000219369};
RA Guldener U.;
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:RKK79273.1, ECO:0000313|Proteomes:UP000285084}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Fo_A13 {ECO:0000313|EMBL:RKK79273.1,
RC ECO:0000313|Proteomes:UP000285084};
RX PubMed=30202022; DOI=10.1038/s41598-018-30335-7;
RA Armitage A.D., Taylor A., Sobczyk M.K., Baxter L., Greenfield B.P.,
RA Bates H.J., Wilson F., Jackson A.C., Ott S., Harrison R.J., Clarkson J.P.;
RT "Characterisation of pathogen-specific regions and novel effector
RT candidates in Fusarium oxysporum f. sp. cepae.";
RL Sci. Rep. 8:13530-13530(2018).
RN [4] {ECO:0000313|EMBL:KAF5259856.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 39464 {ECO:0000313|EMBL:KAF5259856.1};
RA Kim H.-S., Busman M., Brown D.W., Divon H., Uhlig S., Proctor R.H.;
RT "Identification and distribution of gene clusters putatively required for
RT synthesis of sphingolipid metabolism inhibitors in phylogenetically diverse
RT species of the filamentous fungus Fusarium.";
RL Submitted (FEB-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- SIMILARITY: Belongs to the threonine aldolase family.
CC {ECO:0000256|ARBA:ARBA00006966}.
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DR EMBL; JAAFOW010001630; KAF5259856.1; -; Genomic_DNA.
DR EMBL; MRCX01000033; RKK79273.1; -; Genomic_DNA.
DR EMBL; FMJY01000005; SCO85241.1; -; Genomic_DNA.
DR VEuPathDB; FungiDB:FOC1_g10011062; -.
DR VEuPathDB; FungiDB:FOC4_g10009951; -.
DR VEuPathDB; FungiDB:FOIG_12832; -.
DR VEuPathDB; FungiDB:FOMG_10430; -.
DR VEuPathDB; FungiDB:FOXG_06405; -.
DR VEuPathDB; FungiDB:FOZG_07142; -.
DR VEuPathDB; FungiDB:HZS61_012546; -.
DR OrthoDB; 178754at2759; -.
DR Proteomes; UP000219369; Unassembled WGS sequence.
DR Proteomes; UP000285084; Unassembled WGS sequence.
DR Proteomes; UP000558688; Unassembled WGS sequence.
DR GO; GO:0016829; F:lyase activity; IEA:InterPro.
DR GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR001597; ArAA_b-elim_lyase/Thr_aldolase.
DR InterPro; IPR023603; Low_specificity_L-TA-like.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR NCBIfam; NF041359; GntG_guanitoxin; 1.
DR PANTHER; PTHR48097:SF9; L-THREONINE ALDOLASE; 1.
DR PANTHER; PTHR48097; L-THREONINE ALDOLASE-RELATED; 1.
DR Pfam; PF01212; Beta_elim_lyase; 1.
DR PIRSF; PIRSF017617; Thr_aldolase; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000558688}.
FT DOMAIN 29..322
FT /note="Aromatic amino acid beta-eliminating lyase/threonine
FT aldolase"
FT /evidence="ECO:0000259|Pfam:PF01212"
FT MOD_RES 234
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR017617-1"
SQ SEQUENCE 388 AA; 41888 MW; 2EE37BAFAB5EE9E6 CRC64;
MPSLTTPESP FTPKVQAKLL ASREKASRDF RSDVVTVPVE EMMTSILEAS VNDDIYDPEG
DPSVKALEAR LVELTGMEAA LWAVSGTQGN QICLRTHLTQ PPHSVLLDHR AHVHCWESGA
LPVISQASVT TVHAENGVHL TLEDVKKNII ADGNIHFPPT RVVSLENTLS GTILPLADAQ
AISNYVRSFP VPEGQKPIAM HLDGARVFDG VIGEGVDLKA YAACFDSISI CLAKGIGAPM
GSVILGKKPF IERAKWFRKM LGGGTRQPGM MAAAALSALE YSIPRFPSVH AMTKDASARL
EAVGYKFTLP VQTNMILLDL EAAEIPPAAF VEYCAKEDVS VFPMARLVFH HQTSEVAVDK
LVTALTRLME DKRNGVTLND GEAHGGYS
//
