ID   A0A2H3TJG6_FUSOX        Unreviewed;       365 AA.
AC   A0A2H3TJG6;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Related to toxD protein {ECO:0000313|EMBL:SCO88802.1};
GN   ORFNames=FRV6_12929 {ECO:0000313|EMBL:SCO88802.1};
OS   Fusarium oxysporum (Fusarium vascular wilt).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC   Fusarium oxysporum species complex.
OX   NCBI_TaxID=5507 {ECO:0000313|EMBL:SCO88802.1, ECO:0000313|Proteomes:UP000219369};
RN   [1] {ECO:0000313|Proteomes:UP000219369}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=V64-1 {ECO:0000313|Proteomes:UP000219369};
RA   Guldener U.;
RL   Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family. {ECO:0000256|ARBA:ARBA00008072}.
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DR   EMBL; FMJY01000007; SCO88802.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2H3TJG6; -.
DR   VEuPathDB; FungiDB:FOC1_g10001905; -.
DR   VEuPathDB; FungiDB:FOC4_g10002021; -.
DR   VEuPathDB; FungiDB:FOIG_07489; -.
DR   VEuPathDB; FungiDB:FOMG_08812; -.
DR   VEuPathDB; FungiDB:FOXG_12998; -.
DR   VEuPathDB; FungiDB:FOZG_14699; -.
DR   VEuPathDB; FungiDB:HZS61_009148; -.
DR   OrthoDB; 2267374at2759; -.
DR   Proteomes; UP000219369; Unassembled WGS sequence.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0016651; F:oxidoreductase activity, acting on NAD(P)H; IEA:InterPro.
DR   CDD; cd08249; enoyl_reductase_like; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   InterPro; IPR047122; Trans-enoyl_RdTase-like.
DR   PANTHER; PTHR45348; HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG); 1.
DR   PANTHER; PTHR45348:SF2; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C2E1P3.01; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   NADP {ECO:0000256|ARBA:ARBA00022857};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          31..359
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   365 AA;  39109 MW;  BA35F5B12412118D CRC64;
     MTTMKALVSN RSIVTRLINA TRAKAIGGQG GRVQDDVPIP TISSNEILVK VKAVALNPTD
     FKHLDIVSPP NSIIGCDYAG VVHQVGDSAK DRWNIGDRVA GAVHGGLYPD KGAFAEYLKI
     DADLAWRVPD DISDTEATTY GVSAVTAMLV LNVHHGLPFV DTKPTTPKNE AIFIYAGATS
     AGLYHIQLAK AAGYTVVTTA SPRSFQLVKQ YGADVVFDYN SPSVAEDIIK EYPKITKAVD
     CFSEGKSTSI CAAVLKPSGG KVVTLLPNGK SSTPGVTYDL VMSYTAMGHA FQWLPPIGPK
     FEARPQDRAA LVRFYESLPR ITHLLKPIPT IELKNGFDGV LEGLDKLRAG QVAGGKQVVR
     FNIGE
//