ID A0A2H3TMA8_FUSOX Unreviewed; 577 AA.
AC A0A2H3TMA8;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Related to clathrin binding protein ENT2 {ECO:0000313|EMBL:SCO86841.1};
GN ORFNames=BFJ68_g12441 {ECO:0000313|EMBL:RKL01222.1}, BFJ69_g4518
GN {ECO:0000313|EMBL:RKK79998.1}, FOXYS1_5506
GN {ECO:0000313|EMBL:KAF5263732.1}, FRV6_10968
GN {ECO:0000313|EMBL:SCO86841.1};
OS Fusarium oxysporum (Fusarium vascular wilt).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=5507 {ECO:0000313|EMBL:SCO86841.1, ECO:0000313|Proteomes:UP000219369};
RN [1] {ECO:0000313|Proteomes:UP000219369}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=V64-1 {ECO:0000313|Proteomes:UP000219369};
RA Guldener U.;
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:SCO86841.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=V64-1 {ECO:0000313|EMBL:SCO86841.1};
RA Capua I., De Benedictis P., Joannis T., Lombin L.H., Cattoli G.;
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Proteomes:UP000285084, ECO:0000313|Proteomes:UP000285860}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Fo_A13 {ECO:0000313|EMBL:RKK79998.1,
RC ECO:0000313|Proteomes:UP000285084}, and Fo_A28
RC {ECO:0000313|EMBL:RKL01222.1, ECO:0000313|Proteomes:UP000285860};
RX PubMed=30202022; DOI=10.1038/s41598-018-30335-7;
RA Armitage A.D., Taylor A., Sobczyk M.K., Baxter L., Greenfield B.P.,
RA Bates H.J., Wilson F., Jackson A.C., Ott S., Harrison R.J., Clarkson J.P.;
RT "Characterisation of pathogen-specific regions and novel effector
RT candidates in Fusarium oxysporum f. sp. cepae.";
RL Sci. Rep. 8:13530-13530(2018).
RN [4] {ECO:0000313|EMBL:KAF5263732.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 39464 {ECO:0000313|EMBL:KAF5263732.1};
RA Kim H.-S., Busman M., Brown D.W., Divon H., Uhlig S., Proctor R.H.;
RT "Identification and distribution of gene clusters putatively required for
RT synthesis of sphingolipid metabolism inhibitors in phylogenetically diverse
RT species of the filamentous fungus Fusarium.";
RL Submitted (FEB-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the epsin family.
CC {ECO:0000256|ARBA:ARBA00010130}.
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DR EMBL; JAAFOW010000850; KAF5263732.1; -; Genomic_DNA.
DR EMBL; MRCX01000029; RKK79998.1; -; Genomic_DNA.
DR EMBL; MRCY01000081; RKL01222.1; -; Genomic_DNA.
DR EMBL; FMJY01000006; SCO86841.1; -; Genomic_DNA.
DR VEuPathDB; FungiDB:FOC1_g10014714; -.
DR VEuPathDB; FungiDB:FOC4_g10014323; -.
DR VEuPathDB; FungiDB:FOIG_02304; -.
DR VEuPathDB; FungiDB:FOMG_11434; -.
DR VEuPathDB; FungiDB:FOXG_03290; -.
DR VEuPathDB; FungiDB:FOZG_08768; -.
DR VEuPathDB; FungiDB:HZS61_015394; -.
DR OrthoDB; 1532at2759; -.
DR Proteomes; UP000219369; Unassembled WGS sequence.
DR Proteomes; UP000285084; Unassembled WGS sequence.
DR Proteomes; UP000285860; Unassembled WGS sequence.
DR Proteomes; UP000558688; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR CDD; cd16991; ENTH_Ent1_Ent2; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR InterPro; IPR013182; DUF1720.
DR InterPro; IPR013809; ENTH.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR003903; UIM_dom.
DR PANTHER; PTHR12276; EPSIN/ENT-RELATED; 1.
DR PANTHER; PTHR12276:SF110; FI19443P1; 1.
DR Pfam; PF08226; DUF1720; 1.
DR Pfam; PF01417; ENTH; 1.
DR SMART; SM00273; ENTH; 1.
DR SMART; SM00726; UIM; 2.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR PROSITE; PS50942; ENTH; 1.
DR PROSITE; PS50330; UIM; 1.
PE 3: Inferred from homology;
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000558688}.
FT DOMAIN 10..143
FT /note="ENTH"
FT /evidence="ECO:0000259|PROSITE:PS50942"
FT REGION 151..468
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 544..577
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 170..242
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 244..462
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 548..577
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 577 AA; 64919 MW; BC90EBD2C86AE1B7 CRC64;
MSKVMRSVKN VTKGYSSAQV KVREATSNDP WGPTGTQMSE IAQMTYNTST EFYEIMDMID
KRLNDKGKNW RHVLKALKVL DYCLHEGSEL VVTWARQSIY IIKTLREFQY VDEDGRDVGQ
NVRVAAKELT SLILDEERLR AERSDRRSWK SRVTGLEEFA PQHAEPVNHG TRRQQPRRQM
NEEEDAEYRL ALEASKYQEE EDRKKRESRQ NGPDDDDDLA KAIKLSEEEE ERRRRELENS
NAASLFDDDP TPQQQTSQPQ YTGFNQGYQQ GNPVDFFANP IEQNQPQPTG YMNNAYTGFQ
QTQPTGFQPN YNTGFNGQQT GMGFDPYGQQ QQQNQQGFQP QPTGFNPYLQ QQQQQPQQQS
FSSPASPEPT LQPGSNNPWA TNNSQQQLQP TPTGSNNPFA QFSRPQSARP NPISSLGALP
EQKSLNSFGS QPQTQPQLQQ QNSFPLQSQN SFPQSQPSFA APQKEMNEHE TRLNTLLASG
DGMDTFGNTG NLRIPAQHTA PGTFVNSAGA GVARINAEAT GNNPFLRQQF TGMPTVNYGA
QMPAATGPAG MNGQTNNPFA HQQAPQQQQQ NHDLIQF
//
