ID   A0A2H3TNI4_FUSOX        Unreviewed;       387 AA.
AC   A0A2H3TNI4;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Related to toxD protein {ECO:0000313|EMBL:SCO90242.1};
GN   ORFNames=FRV6_14370 {ECO:0000313|EMBL:SCO90242.1};
OS   Fusarium oxysporum (Fusarium vascular wilt).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC   Fusarium oxysporum species complex.
OX   NCBI_TaxID=5507 {ECO:0000313|EMBL:SCO90242.1, ECO:0000313|Proteomes:UP000219369};
RN   [1] {ECO:0000313|Proteomes:UP000219369}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=V64-1 {ECO:0000313|Proteomes:UP000219369};
RA   Guldener U.;
RL   Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family. {ECO:0000256|ARBA:ARBA00008072}.
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DR   EMBL; FMJY01000009; SCO90242.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2H3TNI4; -.
DR   VEuPathDB; FungiDB:FOC1_g10008906; -.
DR   VEuPathDB; FungiDB:FOC4_g10002602; -.
DR   VEuPathDB; FungiDB:FOIG_14762; -.
DR   VEuPathDB; FungiDB:FOMG_13357; -.
DR   VEuPathDB; FungiDB:FOXG_16490; -.
DR   VEuPathDB; FungiDB:FOZG_16659; -.
DR   VEuPathDB; FungiDB:HZS61_005581; -.
DR   OrthoDB; 1589627at2759; -.
DR   Proteomes; UP000219369; Unassembled WGS sequence.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0016651; F:oxidoreductase activity, acting on NAD(P)H; IEA:InterPro.
DR   CDD; cd08249; enoyl_reductase_like; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   InterPro; IPR047122; Trans-enoyl_RdTase-like.
DR   PANTHER; PTHR45348; HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG); 1.
DR   PANTHER; PTHR45348:SF2; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C2E1P3.01; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   NADP {ECO:0000256|ARBA:ARBA00022857};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          8..368
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   387 AA;  41474 MW;  19DE2C7A2CBC0729 CRC64;
     MKALILNTSL KKATVENVDR PAPGSHEILV NVRAIALNPV DELYVSSPIA AQEKRIIGTD
     FAGVVVEAGS EISDLSDPRV KVGTRVAGFL QGASSVNDRP GAFAEHIAVP YDLVWNVPDG
     LTLEEASSIS MCGLTAAQAL FGRLGLPNPF SSGPPRQDVA GSNITSLFIY GSSTSVGLYA
     AQLARIAARV SGMSIRLIGA ASSSKHEMLR NEPYNYDVLV DYKDKDWVQE VKDATNGNGV
     DFALDCISEG QTVYNTHETL APSAKFAVIR GPVGGQYDPA LLTVKPIYGA VWEGLGVEVG
     YNDAVIPANP DSHAFAKEFY NFLSKPLPSG RAQLEPNPVR LMPGGLEKVV QDGFRLLGTG
     LVSGRSKIER PEEYMRPISA EKLVYRL
//