ID   A0A2H3TQ63_FUSOX        Unreviewed;       239 AA.
AC   A0A2H3TQ63;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   27-MAR-2024, entry version 12.
DE   RecName: Full=D-lactate dehydratase {ECO:0000256|ARBA:ARBA00013134};
DE            EC=4.2.1.130 {ECO:0000256|ARBA:ARBA00013134};
GN   ORFNames=FRV6_14902 {ECO:0000313|EMBL:SCO90774.1};
OS   Fusarium oxysporum (Fusarium vascular wilt).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC   Fusarium oxysporum species complex.
OX   NCBI_TaxID=5507 {ECO:0000313|EMBL:SCO90774.1, ECO:0000313|Proteomes:UP000219369};
RN   [1] {ECO:0000313|Proteomes:UP000219369}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=V64-1 {ECO:0000313|Proteomes:UP000219369};
RA   Guldener U.;
RL   Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H2O + methylglyoxal = (R)-lactate + H(+);
CC         Xref=Rhea:RHEA:27754, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16004, ChEBI:CHEBI:17158; EC=4.2.1.130;
CC         Evidence={ECO:0000256|ARBA:ARBA00001524};
CC   -!- SIMILARITY: Belongs to the peptidase C56 family. HSP31-like subfamily.
CC       {ECO:0000256|ARBA:ARBA00038493}.
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DR   EMBL; FMJY01000009; SCO90774.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2H3TQ63; -.
DR   VEuPathDB; FungiDB:FOC1_g10007005; -.
DR   VEuPathDB; FungiDB:FOC4_g10009860; -.
DR   VEuPathDB; FungiDB:FOIG_08774; -.
DR   VEuPathDB; FungiDB:FOMG_15434; -.
DR   VEuPathDB; FungiDB:FOXG_09865; -.
DR   VEuPathDB; FungiDB:FOZG_14125; -.
DR   VEuPathDB; FungiDB:HZS61_006031; -.
DR   OrthoDB; 4342at2759; -.
DR   Proteomes; UP000219369; Unassembled WGS sequence.
DR   Gene3D; 3.40.50.880; -; 1.
DR   InterPro; IPR029062; Class_I_gatase-like.
DR   PANTHER; PTHR48094:SF11; GLUTATHIONE-INDEPENDENT GLYOXALASE HSP31-RELATED; 1.
DR   PANTHER; PTHR48094; PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED; 1.
DR   SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
PE   3: Inferred from homology;
KW   Stress response {ECO:0000256|ARBA:ARBA00023016}.
SQ   SEQUENCE   239 AA;  25748 MW;  B3307DD645B0C25F CRC64;
     MSPPRRALIS ITSASATLFD GKETTGLFIT EALHPYKVLR AAGFEVDLAS ETGTYTPDWL
     SQQPDFLNGD DLAIWNDTNS EFRKKLDNMP KASELDPSKY GLFYASAGHA ALIDYPTASS
     LQNIAAQVWA SGGVVSTVCH GPAIFANLID PTTNEPLIKG KKITGFTTEA ENTMKIMGEL
     RSWGSEMVEE VAARLGATYE RAPGIWDDFH IVDGRLVTGQ NPASATSTAE AAVAVFEKL
//