ID A0A2H3TTF9_FUSOX Unreviewed; 1969 AA.
AC A0A2H3TTF9;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=Probable RNA helicase {ECO:0000313|EMBL:SCO85159.1};
GN ORFNames=FRV6_09286 {ECO:0000313|EMBL:SCO85159.1};
OS Fusarium oxysporum (Fusarium vascular wilt).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=5507 {ECO:0000313|EMBL:SCO85159.1, ECO:0000313|Proteomes:UP000219369};
RN [1] {ECO:0000313|Proteomes:UP000219369}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=V64-1 {ECO:0000313|Proteomes:UP000219369};
RA Guldener U.;
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FMJY01000005; SCO85159.1; -; Genomic_DNA.
DR VEuPathDB; FungiDB:FOC1_g10005192; -.
DR VEuPathDB; FungiDB:FOC4_g10011560; -.
DR VEuPathDB; FungiDB:FOIG_11818; -.
DR VEuPathDB; FungiDB:FOMG_12131; -.
DR VEuPathDB; FungiDB:FOXG_08213; -.
DR VEuPathDB; FungiDB:FOZG_07045; -.
DR VEuPathDB; FungiDB:HZS61_012623; -.
DR OrthoDB; 57056at2759; -.
DR Proteomes; UP000219369; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0010467; P:gene expression; IEA:UniProt.
DR GO; GO:0090304; P:nucleic acid metabolic process; IEA:UniProt.
DR CDD; cd18020; DEXHc_ASCC3_1; 1.
DR CDD; cd18022; DEXHc_ASCC3_2; 1.
DR CDD; cd18795; SF2_C_Ski2; 2.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 2.60.40.150; C2 domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR Gene3D; 1.10.3380.10; Sec63 N-terminal domain-like domain; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004179; Sec63-dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR47961; DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED; 1.
DR PANTHER; PTHR47961:SF13; SEC63 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00270; DEAD; 2.
DR Pfam; PF00271; Helicase_C; 2.
DR Pfam; PF02889; Sec63; 2.
DR PIRSF; PIRSF039073; BRR2; 1.
DR SMART; SM00382; AAA; 2.
DR SMART; SM00487; DEXDc; 2.
DR SMART; SM00490; HELICc; 2.
DR SMART; SM00973; Sec63; 2.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
DR SUPFAM; SSF158702; Sec63 N-terminal domain-like; 2.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 2.
DR PROSITE; PS51194; HELICASE_CTER; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:SCO85159.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 284..477
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 508..711
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 1144..1319
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 1349..1560
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 29..53
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 158..197
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1950..1969
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 158..172
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1969 AA; 220536 MW; AC3E06F1BE630D44 CRC64;
MASSQLSAAE ARWREQFAAM QEAIANLKIP QENGSVEDDL DDDEFGGYSS GNSGQDVWDF
ISDEDQEALS SDFADGEALD GPAVADYGAE WFAVRCSAIA AKNGLSADVF ESQIMSVLDS
DRSDDELQIQ LTDLVGFDDL DFIIEMLGHR NEIISAVNSQ SQGSSSGPRL LSKAQREENL
RRQDQAHKSA TLAPAHSKEP QYPHVYKAYS AGNTLSYAGK KYGLPIGSER LSFDKYEEYF
IPAGKKGVLG PGQRLIPVKE LNGLCRNTFK GYKTLNRMQS LVYPVAHKTS ENMLICAPTG
AGKTDAAMLT ILQTIAQNVE PNPFEDPSAT EFAVNADDFK IVYVAPMKAL AAEVTEKLGK
RLAWLGIKCR EYTGDMQLTK SEIIQTQIIV TTPEKWDVVT RKGTGDTELV QKVRLLIIDE
VHMLHDERGA VLESLVARTE RQVESTQSLI RIVGLSATLP NYVDVADFLK VNKYAGLFYF
DSSFRPVPLE QHFIGVKGKA GSKQSKENLD QVAFDKVKEM LERDHQVMVF VHSRRDTQLT
ARMLHQKAID AMCADLLDPS YHPGFEQASR DIKQSKSKEI RELLSKGIGV HHAGMARSDR
NLMERLFGEG VLKVLCCTAT LAWGVNLPAA AVVIKGTQVY SAQDGKFVDL GILDVLQIFG
RAGRPQFEDT GIGMICTTHD KLTHYLTAVT EQQPIESKFS TKLVDNLNAE IALGTVTSIP
DAVQWIGYSY LFVRMQRSPM SYGIEWSEIR DDPNLVQRRR QLAIQAAKTL QQCQMIIYNE
RTDELRSKDI GRIASQYYIL HTSIQVFNAM MQPQATEADI LKMISMSGEF DNIQSRDSEE
KELTHLRREI IPCDVDGGID TPQAKTNILL QSYISKAQPE DFALSNDMNY VAQQSGRICR
ALFMLALNRR WGHQCLVLLT LAKSIEKRIW PYQHPLHQFD LAKSVLNQLD AKENLTIETM
KDMEPAEIGG LIHNQSAGKN IAKILNNFPT VHVEAEIAPL NRDVLRIKLF VIPDFRWHDQ
IHGTSESFYI WVENSETSEI YHHEFFILNR RKLHDDHELN FTIPLSDPLP SQIYVRAVSD
RWLGAETVTP VSFQHLIRPD TESVYTDLLN LQPLPISALK NPALEELYAK RFEFFNPMQT
QIFHTLYHTP ANVLLGSPTG SGKTVAAELA MWWAFRERPK SKVVYIAPMK ALVRERVKDW
GVRLARPLGL KLVELTGDNT PDTRTIQDAD IIITTPEKWD GISRSWQTRG YVRQVSLVII
DEIHLLAGDR GPILEIIVSR MNYIASSTKN AVRLLGMSTA CANATDLGNW LGVKEGLFNF
KHSVRPVPLE LYIDGFPEVR GFCPLMQSMN RPTFLAVKNH SPDKPVIVFV PSRRQTRLTA
KDLINFCGME DNPRRFLHMD EDDLQLNLAR VKDDALKEAI NFGIGLHHAG LVESDRQLAE
ELFLNNKIQI LVATSTLAWG VNLPAHLVVV KGTQFFDAKI EAYKDMDLTD VLQMLGRAGR
PQFDNSGVAR IFTQDSKKDF YKHFLHTGFP VESSLHTVLD NHLCAEVSAE TIVTKQDALD
YLTWTFFFRR LHKNPSYYGL EISAEEHNSI AAQQLANEYM IEMVSKSLNE LADSKCVEVF
PNGDVDPTPL GKIMSYYYLS HKTIRHLVKH AKAQASFLDV LSWMSRATEY DELPVRHNED
LINNTLSDNL PFPGHAFGLP MWDPHVKAFL LLQAHMSQID LPITDYVGDQ TSVLDQAIRV
IQASIDVLTE LGYLSSCLQM MALLQSIKSA RWPTDAPVSI LPTVEPDVKN DTPIAKISAL
TRPQAMQLAK KLGVPASQHN RFARAVSILP NVEVSIAAAT ALSVTIGLKR LNQLVEREAR
IYAPKFPKPQ TESWFVIVAD LTRDEVIAVK RVGWTTNPNR KLEAGGRPTA KTTIKLPPAQ
AGQARKFDVL VVSDAYPGLE YRVEGVDIPA PPTVDDAVQS KKADASGSK
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