ID A0A2H3TUK8_FUSOX Unreviewed; 442 AA.
AC A0A2H3TUK8;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Fructose-2,6-bisphosphatase {ECO:0000313|EMBL:RKK68173.1};
DE SubName: Full=Probable fructose-2,6-bisphosphate 2-phosphatase {ECO:0000313|EMBL:SCO89421.1};
GN ORFNames=BFJ68_g8556 {ECO:0000313|EMBL:RKL10914.1}, BFJ69_g13833
GN {ECO:0000313|EMBL:RKK68173.1}, FOXYS1_8099
GN {ECO:0000313|EMBL:KAF5261216.1}, FRV6_13549
GN {ECO:0000313|EMBL:SCO89421.1};
OS Fusarium oxysporum (Fusarium vascular wilt).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=5507 {ECO:0000313|EMBL:SCO89421.1, ECO:0000313|Proteomes:UP000219369};
RN [1] {ECO:0000313|Proteomes:UP000219369}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=V64-1 {ECO:0000313|Proteomes:UP000219369};
RA Guldener U.;
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:SCO89421.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=V64-1 {ECO:0000313|EMBL:SCO89421.1};
RA Capua I., De Benedictis P., Joannis T., Lombin L.H., Cattoli G.;
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Proteomes:UP000285084, ECO:0000313|Proteomes:UP000285860}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Fo_A13 {ECO:0000313|EMBL:RKK68173.1,
RC ECO:0000313|Proteomes:UP000285084}, and Fo_A28
RC {ECO:0000313|EMBL:RKL10914.1, ECO:0000313|Proteomes:UP000285860};
RX PubMed=30202022; DOI=10.1038/s41598-018-30335-7;
RA Armitage A.D., Taylor A., Sobczyk M.K., Baxter L., Greenfield B.P.,
RA Bates H.J., Wilson F., Jackson A.C., Ott S., Harrison R.J., Clarkson J.P.;
RT "Characterisation of pathogen-specific regions and novel effector
RT candidates in Fusarium oxysporum f. sp. cepae.";
RL Sci. Rep. 8:13530-13530(2018).
RN [4] {ECO:0000313|EMBL:KAF5261216.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 39464 {ECO:0000313|EMBL:KAF5261216.1};
RA Kim H.-S., Busman M., Brown D.W., Divon H., Uhlig S., Proctor R.H.;
RT "Identification and distribution of gene clusters putatively required for
RT synthesis of sphingolipid metabolism inhibitors in phylogenetically diverse
RT species of the filamentous fungus Fusarium.";
RL Submitted (FEB-2020) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; JAAFOW010001316; KAF5261216.1; -; Genomic_DNA.
DR EMBL; MRCX01000197; RKK68173.1; -; Genomic_DNA.
DR EMBL; MRCY01000039; RKL10914.1; -; Genomic_DNA.
DR EMBL; FMJY01000008; SCO89421.1; -; Genomic_DNA.
DR VEuPathDB; FungiDB:FOC1_g10007294; -.
DR VEuPathDB; FungiDB:FOC4_g10011090; -.
DR VEuPathDB; FungiDB:FOIG_04418; -.
DR VEuPathDB; FungiDB:FOMG_10305; -.
DR VEuPathDB; FungiDB:FOXG_13893; -.
DR VEuPathDB; FungiDB:FOZG_11329; -.
DR VEuPathDB; FungiDB:HZS61_016344; -.
DR OrthoDB; 2013830at2759; -.
DR Proteomes; UP000219369; Unassembled WGS sequence.
DR Proteomes; UP000285084; Unassembled WGS sequence.
DR Proteomes; UP000285860; Unassembled WGS sequence.
DR Proteomes; UP000558688; Unassembled WGS sequence.
DR GO; GO:0003873; F:6-phosphofructo-2-kinase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006003; P:fructose 2,6-bisphosphate metabolic process; IEA:InterPro.
DR GO; GO:0006000; P:fructose metabolic process; IEA:InterPro.
DR CDD; cd07067; HP_PGM_like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.1240; Phosphoglycerate mutase-like; 1.
DR InterPro; IPR003094; 6Pfruct_kin.
DR InterPro; IPR013079; 6Phosfructo_kin.
DR InterPro; IPR013078; His_Pase_superF_clade-1.
DR InterPro; IPR029033; His_PPase_superfam.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001345; PG/BPGM_mutase_AS.
DR PANTHER; PTHR10606:SF44; 6-PHOSPHOFRUCTO 2-KINASE_FRUCTOSE 2,6-BISPHOSPHATASE LONG FORM; 1.
DR PANTHER; PTHR10606; 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE; 1.
DR Pfam; PF01591; 6PF2K; 1.
DR Pfam; PF00300; His_Phos_1; 1.
DR PIRSF; PIRSF000709; 6PFK_2-Ptase; 1.
DR PRINTS; PR00991; 6PFRUCTKNASE.
DR SMART; SM00855; PGAM; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF53254; Phosphoglycerate mutase-like; 1.
DR PROSITE; PS00175; PG_MUTASE; 1.
PE 4: Predicted;
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000558688}.
FT DOMAIN 11..225
FT /note="6-phosphofructo-2-kinase"
FT /evidence="ECO:0000259|Pfam:PF01591"
SQ SEQUENCE 442 AA; 50690 MW; AB4433EA5B9BD3C1 CRC64;
MPSRTNGVGV QAEDTRICVV MVGLPARGKS YIAQRAQRYL QWLSIPAQTF NVGNYRRNDA
PQPTADFFDI NNPEGERTRR AAAEAAVADM LAWFRSGGIV GILDATNSTL ERRKWVLEVC
NENGIEVLFV ESKCDDEELI MANIRDVKTT SPDYRGQDPE TAALDFRNRI RNYEKVYCTI
DADGKESHLT YLKIMDVGKQ VIISRIRDYL QSRIVYYLMN LHIRPRSVWL SRHGESLYNI
DGRIGGDTLL SPRGEQYARK LPELVRKSVG DDRPLTVWTS TLRRTIATSR FLPQHYNQLQ
WKALDELDSG VCDGLTYQEI KDRYPEDFAA RDEDKYNYRY RGGESYRDVV IRLEPIIMEL
ERSEDILIVT HQAVLRCIYA YFMKKDQSKS PWMNVPLHTL IKLTPGAYGT EEVRYEANIP
AVSTWRGKGS TAKHENPAPG VM
//
