ID   A0A2H5AVP6_9ACTN        Unreviewed;       950 AA.
AC   A0A2H5AVP6;
DT   28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   SubName: Full=RNA helicase {ECO:0000313|EMBL:AUG76160.1};
GN   ORFNames=CFP65_1258 {ECO:0000313|EMBL:AUG76160.1};
OS   Kitasatospora sp. MMS16-BH015.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Kitasatospora.
OX   NCBI_TaxID=2018025 {ECO:0000313|EMBL:AUG76160.1, ECO:0000313|Proteomes:UP000239175};
RN   [1] {ECO:0000313|EMBL:AUG76160.1, ECO:0000313|Proteomes:UP000239175}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MMS16-BH015 {ECO:0000313|EMBL:AUG76160.1,
RC   ECO:0000313|Proteomes:UP000239175};
RA   Kim S.B., Yun B.-R.;
RT   "Genome sequence of Kitasatospora sp. MMS16-BH015.";
RL   Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP025394; AUG76160.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2H5AVP6; -.
DR   KEGG; kit:CFP65_1258; -.
DR   OrthoDB; 3229913at2; -.
DR   Proteomes; UP000239175; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd18795; SF2_C_Ski2; 1.
DR   Gene3D; 1.10.3380.30; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR012961; Ski2/MTR4_C.
DR   PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR   PANTHER; PTHR12131:SF8; HELICASE SKI2W; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF08148; DSHCT; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM01142; DSHCT; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:AUG76160.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000239175}.
FT   DOMAIN          51..209
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          296..500
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   REGION          235..291
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          663..701
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        680..701
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   950 AA;  105157 MW;  70F156D451BF9618 CRC64;
     MTGAVPDDQG ELSPAEAYAA FRRRAKEQKT ALYGFKELYD FPLDPFQIEA CQALEEGTGV
     LVAAPTGSGK TIVGEFAVHL ALTQGRKCFY TTPIKALSNQ KFGDLVKRYG ADKVGLLTGD
     NSVNGDAPVV VMTTEVLRNM LYAGSSALDG LGYVVMDEVH YLADRFRGAV WEEVIIHLPE
     SVVLASLSAT VSNAEEFGDW LHTVRGGTKV IVSEHRPVPL WQHVMAGNRM YDLFANPDRD
     GRPKDAPRNP AKAVNPELVR LSRSEQAGNP RGGDRFQRGR GRSMPTGRPT RVWTPGRVDV
     IDRLDSEGLL PAITFIFSRA ACEAAVQQCL SSGLRLNREA DRALVREIVE ERCADIPDED
     LHVLGYFEWL DGLERGIAAH HAGMLPRFKE VVEELFVKGL VKAVFATETL ALGINMPARS
     VVLEKLVKWN GETHADITPG EYTQLTGRAG RRGIDVEGHA VVLWQRGLDP EALAGLAGTR
     TYPLKSSFRP SYNMAVNLVA QFGRRRSREL LETSFAQFQA DRSVVGIARQ VQRNEEGLEG
     YRESMTCHLG DFQEYMRLRR ELKERENELA REGTGQRRAA AVDAIEQLKP GDVIHVPTGK
     FAGLALVLDP GLPPVSRSPR SHRHPDYQDG PRPVVLTAER QVKRLAMIDF PYPVTAVDRM
     KIPKSFNPRS PQSRRDLASA LRTKAGHLEP ERYRRGRAAA ADDPEIARLR TTLRQHPCHG
     CDEREDHARW AERYHRLTRD TELLERKVKS RTNTIARTFD RVCGLLTDLG YLEGDTVTPD
     GKRLGRLYGE LDLLASECIR EGVWSGLAAA ELAACASALV YEARQADDAA APRVPEGGAK
     EALGHMVRIW GHLDALEEQH RISTAEGVGQ REPDLGFAWT AYRWALGHNL DSVLRDADMP
     AGDFVRWTKQ LIDVLGQIQD AAGDDVALRS TARKAVDGLR RGIIAYSSVG
//