ID   A0A2H5AW44_9ACTN        Unreviewed;       412 AA.
AC   A0A2H5AW44;
DT   28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   SubName: Full=Pyridine nucleotide-disulfide oxidoreductase {ECO:0000313|EMBL:AUG76378.1};
GN   ORFNames=CFP65_1482 {ECO:0000313|EMBL:AUG76378.1};
OS   Kitasatospora sp. MMS16-BH015.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Kitasatospora.
OX   NCBI_TaxID=2018025 {ECO:0000313|EMBL:AUG76378.1, ECO:0000313|Proteomes:UP000239175};
RN   [1] {ECO:0000313|EMBL:AUG76378.1, ECO:0000313|Proteomes:UP000239175}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MMS16-BH015 {ECO:0000313|EMBL:AUG76378.1,
RC   ECO:0000313|Proteomes:UP000239175};
RA   Kim S.B., Yun B.-R.;
RT   "Genome sequence of Kitasatospora sp. MMS16-BH015.";
RL   Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP025394; AUG76378.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2H5AW44; -.
DR   KEGG; kit:CFP65_1482; -.
DR   Proteomes; UP000239175; Chromosome.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 3.30.390.30; -; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR023753; FAD/NAD-binding_dom.
DR   InterPro; IPR016156; FAD/NAD-linked_Rdtase_dimer_sf.
DR   InterPro; IPR028202; Reductase_C.
DR   PANTHER; PTHR43557; APOPTOSIS-INDUCING FACTOR 1; 1.
DR   PANTHER; PTHR43557:SF2; RIESKE DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR   Pfam; PF07992; Pyr_redox_2; 1.
DR   Pfam; PF14759; Reductase_C; 1.
DR   PRINTS; PR00368; FADPNR.
DR   PRINTS; PR00411; PNDRDTASEI.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 2.
DR   SUPFAM; SSF55424; FAD/NAD-linked reductases, dimerisation (C-terminal) domain; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000239175}.
FT   DOMAIN          14..303
FT                   /note="FAD/NAD(P)-binding"
FT                   /evidence="ECO:0000259|Pfam:PF07992"
FT   DOMAIN          323..408
FT                   /note="Reductase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14759"
SQ   SEQUENCE   412 AA;  44810 MW;  257F01E67C248104 CRC64;
     MAEPRKWLAM GGAYVVVGAG LAGAKAVETL REEGFDGPLV LIGAEAERPY ERPPLSKGYL
     QGKAGRETVF VHPPEWYVEH RVDLRTGVTV TEIDRSGHTV RLDGRSLVGY QKLLLATGAE
     PRRLPVPGGD RALLLRTLGD SERLRAGFRR GAKLVVIGAG WIGLEAAAAA REAGCEVTVL
     EAAALPLLRV LGREAAEVFA ELHRAHGVRM RFDVRVSELT ERGVLLGDGE LVEADTVLAG
     VGVAPRTELA EAAGLTVQNG IRTDARLRTS DPDVYAAGDV ANADHPLLRR AVRVEHWANA
     LHQPRTAARA MLGQDAVYDR VPYFFTDQYD LGMEYTGYVE PGGYDRVVFR GDVDGREFIA
     FWLAQGRVLA GMNVNVWDVT DPIRALVRSD RAVDPARLAD PDVPLDEVFE QG
//