ID   A0A2H5B8H3_9ACTN        Unreviewed;       617 AA.
AC   A0A2H5B8H3;
DT   28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=Glucose-methanol-choline oxidoreductase {ECO:0000313|EMBL:AUG80660.1};
GN   ORFNames=CFP65_5986 {ECO:0000313|EMBL:AUG80660.1};
OS   Kitasatospora sp. MMS16-BH015.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Kitasatospora.
OX   NCBI_TaxID=2018025 {ECO:0000313|EMBL:AUG80660.1, ECO:0000313|Proteomes:UP000239175};
RN   [1] {ECO:0000313|EMBL:AUG80660.1, ECO:0000313|Proteomes:UP000239175}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MMS16-BH015 {ECO:0000313|EMBL:AUG80660.1,
RC   ECO:0000313|Proteomes:UP000239175};
RA   Kim S.B., Yun B.-R.;
RT   "Genome sequence of Kitasatospora sp. MMS16-BH015.";
RL   Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
CC   -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC       {ECO:0000256|ARBA:ARBA00010790}.
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DR   EMBL; CP025394; AUG80660.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2H5B8H3; -.
DR   KEGG; kit:CFP65_5986; -.
DR   OrthoDB; 9798604at2; -.
DR   Proteomes; UP000239175; Chromosome.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR000172; GMC_OxRdtase_N.
DR   InterPro; IPR007867; GMC_OxRtase_C.
DR   PANTHER; PTHR42784; PYRANOSE 2-OXIDASE; 1.
DR   PANTHER; PTHR42784:SF1; PYRANOSE 2-OXIDASE; 1.
DR   Pfam; PF05199; GMC_oxred_C; 1.
DR   Pfam; PF00732; GMC_oxred_N; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000239175}.
FT   DOMAIN          228..344
FT                   /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00732"
FT   DOMAIN          448..581
FT                   /note="Glucose-methanol-choline oxidoreductase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05199"
FT   REGION          592..617
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        592..609
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   617 AA;  65680 MW;  AE0E1C25A2420D8B CRC64;
     MAEQTYDVVV VGAGIAGSLL AGQLGARGWR VLVLEAGTGG GDPAREQAEA LARYRGAPAK
     VPSAALAANP AVPSPDVPEL TGLPDGGYRA EGYLRQQGPQ PYASGYLRVN GGTGTAWTGL
     TPRMHPEDFR TGAFGYGRDW PLDYLELEPW YRAAERELGV AADAAEQRAE VGLPLPEGYE
     FPLPAVAASH LDQLLAERLD GAAVQDPYLQ HPTGLKVVGT PHARNTKATE QYGPACQGSA
     SCIPVCPTQA KYTPARTQAG WSAGVRLRTR AVATRVLVDA TGLAAGVSYR GYDEQGRPDP
     TERTARAGLV VLAAHAIENA RLLLASPVAD ASGQLGRNLM DHPVLLTWGL MDRQVGPYRG
     PGSTSGFEGF RFGAGRAARA PFRIEIGNWG WGWAAGPPGL ELDALLRTGD PAFPDGRGLF
     GKALREAVGD RVGRQFALQF ELEQEADPAN RVTLDHRHPD AFGQPRPLID YRLSEHVKRG
     IAAAKAVSDQ LFTLLGAEDH SSYRPGPANP GWYEYQGRPY VYRGAGHAGG THVMGRHPGD
     SVVDSFQRCW SHPNLYAVGC GSMPSLGTSN PTLTMAALAL RTADRIHGEL TSARRSLTTS
     RSAVTRESGP TEETAAR
//