ID A0A2H5BAM3_9ACTN Unreviewed; 450 AA.
AC A0A2H5BAM3;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=GntR family transcriptional regulator {ECO:0000313|EMBL:AUG81443.1};
GN ORFNames=CFP65_6805 {ECO:0000313|EMBL:AUG81443.1};
OS Kitasatospora sp. MMS16-BH015.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Kitasatospora.
OX NCBI_TaxID=2018025 {ECO:0000313|EMBL:AUG81443.1, ECO:0000313|Proteomes:UP000239175};
RN [1] {ECO:0000313|EMBL:AUG81443.1, ECO:0000313|Proteomes:UP000239175}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MMS16-BH015 {ECO:0000313|EMBL:AUG81443.1,
RC ECO:0000313|Proteomes:UP000239175};
RA Kim S.B., Yun B.-R.;
RT "Genome sequence of Kitasatospora sp. MMS16-BH015.";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: In the C-terminal section; belongs to the class-I
CC pyridoxal-phosphate-dependent aminotransferase family.
CC {ECO:0000256|ARBA:ARBA00005384}.
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DR EMBL; CP025394; AUG81443.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2H5BAM3; -.
DR KEGG; kit:CFP65_6805; -.
DR OrthoDB; 4336542at2; -.
DR Proteomes; UP000239175; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00609; AAT_like; 1.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46577; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR PANTHER; PTHR46577:SF1; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR Pfam; PF00392; GntR; 1.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000239175};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 9..77
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
SQ SEQUENCE 450 AA; 46567 MW; 86947B88B2F0F58A CRC64;
MLGDYRITGR RANEIAADIE RAVGAGRLQP GAALPPLRDL AGELGVNPNT VAAAYRLLRD
RGVIETAGRK GSRVRPRPVT TPRDQVRIPV PPGARDLSLG NPDPALLPAL APALAVAAAT
ADRTPVLYGA PPADPALLAL AGASFRADGA PEGELAVCSG SLDAIERVLT TQLRPGDTVA
VEDPGWGSLL DLLPALGLRP VPVLLDDEGP LPASLAEALA AGARAAVVTV RAQNPTGAAL
TARRAAELRA VLAAHPETVL IEDDHGHGMV DQPYESLAVG PGGVLTLARW AVVRSASKAY
GPDLRLAVMC GEPDVVARVL GRQRLDTGWV SLLLQHTVAE LWRTDAAPAG RVAAAYRERR
AALLAALAQR GIRAHGESGL NVWVPVPEES GVVAALVQHG WVVAPGARFR LQSPPGVRIT
VAELSPAEAT RLAADLASVL GSAVGHSRLS
//
