ID A0A2H5N5B3_CITUN Unreviewed; 771 AA.
AC A0A2H5N5B3;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Calcium permeable stress-gated cation channel 1 {ECO:0008006|Google:ProtNLM};
GN ORFNames=CUMW_015240 {ECO:0000313|EMBL:GAY35262.1};
OS Citrus unshiu (Satsuma mandarin) (Citrus nobilis var. unshiu).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus.
OX NCBI_TaxID=55188 {ECO:0000313|EMBL:GAY35262.1};
RN [1] {ECO:0000313|EMBL:GAY35262.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=29259619; DOI=10.3389/fgene.2017.00180;
RA Shimizu T., Tanizawa Y., Mochizuki T., Nagasaki H., Yoshioka T., Toyoda A.,
RA Fujiyama A., Kaminuma E., Nakamura Y.;
RT "Draft sequencing of the heterozygous diploid genome of Satsuma (Citrus
RT unshiu Marc.) using a hybrid assembly approach.";
RL Front. Genet. 8:180-180(2017).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAY35262.1}.
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DR EMBL; BDQV01000003; GAY35262.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2H5N5B3; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR PANTHER; PTHR13018:SF93; PROTEIN OSCA1; 1.
DR Pfam; PF14703; PHM7_cyt; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023303};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 97..120
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 159..178
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 376..400
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 420..447
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 468..487
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 516..535
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 575..605
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 653..671
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 7..180
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 201..363
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 374..646
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
FT REGION 738..771
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 739..761
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 771 AA; 88257 MW; D46C6B7F7618081D CRC64;
MATLADIGVS AALNILGAFV FLIAFAILRL QPFNDRVYFP KWYLKGLRDS PTHGGAFVRK
FVNLDFRSYI RFLNWMPEAL KMPEPELIEH AGLDSAVYLR IYLIGLKIFV PIALVAWSVL
VPVNWTNDTL DVAIKISNVT ASDIDKLSIS NVPLKSQRFW THVVMAYAFT FWTCYVLLKE
YEKVANLRLQ FVASEKRRPD QFTVLVRNVP PDPDESVSEL VEHFFLVNHP NHYLTHQVVV
NANKLAKLVK KKKKLQNWLD YYQLKHSRNN SKRPMMKTGF LGLWGEKVDG IDYHISEIEK
LSKEIAEERE RVVSDPKAIM PAAFVSFNSR WGAAVCAQTQ QTRNPTLWLT EWASEPRDVY
WQNLAIPYVS LSVRRLIMGV AFFFLTFFFM IPIAIVQSFA SIEGIEKAVP FLRPVIEAKF
IKSVIQGFLP GIALKLFLIF LPTILMIMSK FEGFISLSSL ERRAATRYYL FNFVNVFLGS
IIAGSAFEQL NSFLKQSAND IPKTIGIAIP KKATFFITYI MVDGWAGIAA EILMLKPLII
FHLKNFFLVK TEKDREEAMD PGSLGFNIGE PRIQFYFLLG LVYATVTPLL LPFIIVFFAL
AYVVFRHQII NVYNQRYESA AAFWPDVHRR IIAALIISQL LLMGLLSTKK AALSTPFLIA
LPVLTIWFHY FSKDRYESAF VKYPLQEAMM KDTLERAREP NLNLKGYLRN AYIHPVFKGE
DDDDALFEKE ENENVLVLTK RQSRRNTPVP SKMSGASSPS LPEVVQEDPE P
//
