ID A0A2H5PCE1_CITUN Unreviewed; 715 AA.
AC A0A2H5PCE1;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=CSC1/OSCA1-like 7TM region domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CUMW_123650 {ECO:0000313|EMBL:GAY50039.1};
OS Citrus unshiu (Satsuma mandarin) (Citrus nobilis var. unshiu).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus.
OX NCBI_TaxID=55188 {ECO:0000313|EMBL:GAY50039.1};
RN [1] {ECO:0000313|EMBL:GAY50039.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=29259619; DOI=10.3389/fgene.2017.00180;
RA Shimizu T., Tanizawa Y., Mochizuki T., Nagasaki H., Yoshioka T., Toyoda A.,
RA Fujiyama A., Kaminuma E., Nakamura Y.;
RT "Draft sequencing of the heterozygous diploid genome of Satsuma (Citrus
RT unshiu Marc.) using a hybrid assembly approach.";
RL Front. Genet. 8:180-180(2017).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAY50039.1}.
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DR EMBL; BDQV01000058; GAY50039.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2H5PCE1; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR PANTHER; PTHR13018:SF117; CSC1-LIKE PROTEIN RXW8; 1.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR Pfam; PF14703; PHM7_cyt; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023303};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 86..110
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 147..167
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 354..378
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 398..419
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 446..465
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 546..578
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 599..621
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 627..645
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 5..168
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 189..341
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 352..619
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
SQ SEQUENCE 715 AA; 80845 MW; E453728343635C99 CRC64;
MDVSALLTSA GINISVTSLL LSVYSILRKR PSNLSVYFGK RLASVGNRLD DSFSLERFAS
SSSWIVKAWE TSEDEILAIG GMDAVIIIRI IVFSIRIFSI AAIICILLVL PVNYYGNDII
HMEISSESLE VFTIANVEEG SKWYRQFWVH CLALHVISWS ACVLLYFEYK SITRTRLAHI
TGSPPDPSHF TVLVRAVPWS SEHSYSDSVK QFFMNYYSSS YLSHQIVYRA STVRKLMNDA
ENMCQLVKNF STEEKSKLSL LPCLCGKPNS FEVLSDESDS VRENIGFDIS DLASEKEYAV
AFVYFKTRYA AIVAAEVLHS ENPMLWVTEL APEPNDVLWS NLCIPYRQLW FRKIAILLAA
IAFMIVFLAP VAFVQGLTRL HQLSHAFPFL KGMFKQKYIK QLVTGYLPSV ILILFQYAVP
PTMMLFSTVE GSVSHSGRKR SACIKVLSFT IWNVFFVNVL SGSIMGQLNA ISSVKIILNQ
LAAAVPIQAS FFMTYVLTSG WASLAVEMVQ PLGLVYNTMK KCVCRIKEDQ PNGFLSFPYH
TEVSKLLMFG FLGFICSVMA PLILPLLLIY FVLAYLVYKN QIINVYTTDY ESGGKFWPIA
HNSTIVSLVL TQIIALGVFG IKRSTVAFGF TIPLIFGTLL FNEYCRQRFF PTFTKMSAQV
LTEMDRQDEQ GGRMEEIYQQ LRSAYCQFRL ISQDLCKSGR MDHQGDQNSI RIHSQ
//
