ID A0A2H5PCX5_CITUN Unreviewed; 879 AA.
AC A0A2H5PCX5;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=RING-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012483};
DE EC=2.3.2.27 {ECO:0000256|ARBA:ARBA00012483};
DE Flags: Fragment;
GN ORFNames=CUMW_125040 {ECO:0000313|EMBL:GAY50236.1};
OS Citrus unshiu (Satsuma mandarin) (Citrus nobilis var. unshiu).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus.
OX NCBI_TaxID=55188 {ECO:0000313|EMBL:GAY50236.1};
RN [1] {ECO:0000313|EMBL:GAY50236.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=29259619; DOI=10.3389/fgene.2017.00180;
RA Shimizu T., Tanizawa Y., Mochizuki T., Nagasaki H., Yoshioka T., Toyoda A.,
RA Fujiyama A., Kaminuma E., Nakamura Y.;
RT "Draft sequencing of the heterozygous diploid genome of Satsuma (Citrus
RT unshiu Marc.) using a hybrid assembly approach.";
RL Front. Genet. 8:180-180(2017).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC EC=2.3.2.27; Evidence={ECO:0000256|ARBA:ARBA00000900};
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAY50236.1}.
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DR EMBL; BDQV01000060; GAY50236.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2H5PCX5; -.
DR UniPathway; UPA00143; -.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd16664; RING-Ubox_PUB; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR045210; RING-Ubox_PUB.
DR InterPro; IPR003613; Ubox_domain.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR23315; U BOX DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR23315:SF7; U-BOX DOMAIN-CONTAINING PROTEIN 4; 1.
DR Pfam; PF00514; Arm; 3.
DR Pfam; PF04564; U-box; 1.
DR SMART; SM00185; ARM; 5.
DR SMART; SM00504; Ubox; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50176; ARM_REPEAT; 4.
DR PROSITE; PS51698; U_BOX; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 286..360
FT /note="U-box"
FT /evidence="ECO:0000259|PROSITE:PS51698"
FT REPEAT 636..678
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 677..719
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 718..760
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 759..800
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REGION 394..443
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 517..556
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 230..257
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 394..441
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 517..539
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:GAY50236.1"
SQ SEQUENCE 879 AA; 95866 MW; 3EC680031B7C140D CRC64;
IVIPVLGSAQ RIASRRISIP ANVALDSTSS WSGCIDFVSG CEKVVLEWLP KESGMEISLL
KVLLKKISSF LHLSSFDSIK LDIVKKYYQR AEEILKLLKP ILDAIVDSDV ASDEVLYKAF
EEFGQSIDEL KELIENWQPL LSRVLQVESL MSKIRTSGLD IMLQLKSSLQ YFPGELSSTS
LELCSQKIKH MEYEQTSSLI KEAIRDQVDG VAPSSEILVK VAESLSLRSN QEILIEAVAL
EKLKENAEQA EKAGEAEFMD QMISLVTRMH DRLVMIKQSQ ICSPVPIPSD FCCPLSLELM
TDPVIVASGQ TYERAFIKKW IDLGLFVCPK TRQTLAHTTL IPNYTVKALI ANWCELNNVK
LPDPTKTVSL NQPSPLFVHA DSNAPRDSHI FPHTRGNQQI MPESTRSTNS PAKNLVSSNN
TREGGSPLHP HSTSETSYSG IAGNGPGLDI ARISLTSSED RFSNSEERSM ELIGQPSMSK
SIKEFPATID TSEQSSHIHN RTASASSVLS NLNLSQGDAN ETSELSNHSD ASGEGKLESQ
PATTMRREPE FPSRVMETRS RSQVIWRRPS ERFVPRIVST SGAETRADLS GIETQVRKLV
EDLKSTSLDT QREATAELRL LAKHNMDNRM VIANCGAINI LVDLLHSSEI KIQENAVTAL
LNLSINDNNK SAIANANAIE PLIHVLQTGS PEARENAAAT LFSLSVIEDN KIKIGRSGAI
GPLVDLLGNG TPRGKKDAAT ALFNLSIYHE NKARIVQAGA VKHLVDLMDP AAGMVDKAVA
VLANLATIPD GRVAIGQENG IPVLVEVVEL GSARGKENAA AALLQLCTNS SRFCSMVLQE
GAVPPLVALS QSGTPRAKEK AQALLSYFRN QRHGNAGRG
//
