ID A0A2H5PEF2_CITUN Unreviewed; 530 AA.
AC A0A2H5PEF2;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=cycloartenol synthase {ECO:0000256|ARBA:ARBA00039070};
DE EC=5.4.99.8 {ECO:0000256|ARBA:ARBA00039070};
GN ORFNames=CUMW_129110 {ECO:0000313|EMBL:GAY50746.1};
OS Citrus unshiu (Satsuma mandarin) (Citrus nobilis var. unshiu).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus.
OX NCBI_TaxID=55188 {ECO:0000313|EMBL:GAY50746.1};
RN [1] {ECO:0000313|EMBL:GAY50746.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=29259619; DOI=10.3389/fgene.2017.00180;
RA Shimizu T., Tanizawa Y., Mochizuki T., Nagasaki H., Yoshioka T., Toyoda A.,
RA Fujiyama A., Kaminuma E., Nakamura Y.;
RT "Draft sequencing of the heterozygous diploid genome of Satsuma (Citrus
RT unshiu Marc.) using a hybrid assembly approach.";
RL Front. Genet. 8:180-180(2017).
CC -!- SIMILARITY: Belongs to the terpene cyclase/mutase family.
CC {ECO:0000256|ARBA:ARBA00009755}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAY50746.1}.
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DR EMBL; BDQV01000065; GAY50746.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2H5PEF2; -.
DR GO; GO:0005811; C:lipid droplet; IEA:InterPro.
DR GO; GO:0016871; F:cycloartenol synthase activity; IEA:UniProt.
DR GO; GO:1901362; P:organic cyclic compound biosynthetic process; IEA:UniProt.
DR GO; GO:0016104; P:triterpenoid biosynthetic process; IEA:InterPro.
DR CDD; cd02892; SQCY_1; 1.
DR Gene3D; 1.50.10.20; -; 1.
DR InterPro; IPR032696; SQ_cyclase_C.
DR InterPro; IPR018333; Squalene_cyclase.
DR InterPro; IPR002365; Terpene_synthase_CS.
DR InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR NCBIfam; TIGR01787; squalene_cyclas; 1.
DR PANTHER; PTHR11764:SF20; LANOSTEROL SYNTHASE; 1.
DR PANTHER; PTHR11764; TERPENE CYCLASE/MUTASE FAMILY MEMBER; 1.
DR Pfam; PF13243; SQHop_cyclase_C; 2.
DR SFLD; SFLDG01016; Prenyltransferase_Like_2; 1.
DR SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 1.
DR PROSITE; PS01074; TERPENE_SYNTHASES; 1.
PE 3: Inferred from homology;
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 160..445
FT /note="Squalene cyclase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13243"
FT DOMAIN 461..522
FT /note="Squalene cyclase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13243"
SQ SEQUENCE 530 AA; 60491 MW; BC71EF8F8633B883 CRC64;
MWCHCRMVYL PMSYLYGKRF VGPITPTVLA LRKELFTVPY HEIDWNEARN LCAKEDLYYP
HPLIQDVLWA TLDKVVEPLL MHWPGKKLRE KALRNAIKHI HYEDENTRYL CIGPVNKVLN
MLCCWVEDPN SEAFKLHIPR VNDYLWIAED GMKVQGYNGS QLWDTAFAVQ AIISTNLVEE
YGATLKKAHK YIKDSQVLED CPGNLDFWYR HISKGAWPFS TADHGWPISD CTSEGLKASL
LLSKLSSAIV GEPIETKRLY DSVNVIFSLQ NADGGFATYE LMRSYPWLEV LNPAETFGDI
VIDYPCVECT SASIQALTSF KKLYPGHWQE DVDHCIKRAV KFIEKIQELD GSWYGSWGVC
FTYGTWFGVK GLVAAGMNYS NSSTIRKACE FLLSKQRPSG GWGESYLSCQ KKVYSNLEGD
RSHVVNTAWA MLALIDAGQV RINCCCSTLK VTLSLSHAYK LIGQAETDPT PLHRAARYLI
NSQMENGDYP QEEIMGVFNR NCMISYSAYR NIFPIWALGE YRCRVLEAHM
//
