ID A0A2H5Q3H9_CITUN Unreviewed; 507 AA.
AC A0A2H5Q3H9;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 08-NOV-2023, entry version 18.
DE RecName: Full=Carotenoid oxygenase {ECO:0008006|Google:ProtNLM};
GN ORFNames=CUMW_192310 {ECO:0000313|EMBL:GAY59144.1};
OS Citrus unshiu (Satsuma mandarin) (Citrus nobilis var. unshiu).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus.
OX NCBI_TaxID=55188 {ECO:0000313|EMBL:GAY59144.1, ECO:0000313|Proteomes:UP000236630};
RN [1] {ECO:0000313|EMBL:GAY59144.1, ECO:0000313|Proteomes:UP000236630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Miyagawa wase {ECO:0000313|Proteomes:UP000236630};
RX PubMed=29259619; DOI=10.3389/fgene.2017.00180;
RA Shimizu T., Tanizawa Y., Mochizuki T., Nagasaki H., Yoshioka T., Toyoda A.,
RA Fujiyama A., Kaminuma E., Nakamura Y.;
RT "Draft sequencing of the heterozygous diploid genome of Satsuma (Citrus
RT unshiu Marc.) using a hybrid assembly approach.";
RL Front. Genet. 8:180-180(2017).
CC -!- COFACTOR:
CC Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC Evidence={ECO:0000256|PIRSR:PIRSR604294-1};
CC Note=Binds 1 Fe(2+) ion per subunit. {ECO:0000256|PIRSR:PIRSR604294-1};
CC -!- SIMILARITY: Belongs to the carotenoid oxygenase family.
CC {ECO:0000256|ARBA:ARBA00006787}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAY59144.1}.
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DR EMBL; BDQV01000204; GAY59144.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2H5Q3H9; -.
DR STRING; 55188.A0A2H5Q3H9; -.
DR Proteomes; UP000236630; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:InterPro.
DR InterPro; IPR004294; Carotenoid_Oase.
DR PANTHER; PTHR10543; BETA-CAROTENE DIOXYGENASE; 1.
DR PANTHER; PTHR10543:SF58; CAROTENOID CLEAVAGE DIOXYGENASE 4, CHLOROPLASTIC-RELATED; 1.
DR Pfam; PF03055; RPE65; 2.
PE 3: Inferred from homology;
KW Dioxygenase {ECO:0000256|ARBA:ARBA00022964};
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|PIRSR:PIRSR604294-1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|PIRSR:PIRSR604294-1};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00022964};
KW Reference proteome {ECO:0000313|Proteomes:UP000236630}.
FT BINDING 257
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 307
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 373
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
SQ SEQUENCE 507 AA; 57392 MW; FFE0A6AFABE76474 CRC64;
MDHMNYSSLK ISYNHPPKPK ITYYNHTNEQ IIPFLPFQKP KRCVPIQSSM KKNSSCDTKS
SPSLFTNIID RPLHPSVDPK HVFTGNFAPV DELGPTECPV VDGRLPDSLT GTYIRNGPNP
QHMPRGPLHF FEGDGMLHSV QLSKGRAIYT NRYVKTYKYK LERDAGCQIF PNMLSGIYGI
ADIIQCVAAV ARVLMGHINL KKGFGLANTS LAFFSSKLLA LGESDLPYII NSTREGDVET
VGRWDFDEAL FASMTAHPKT DMTTKETFAF KFSPVFSPHL TFFRFDANSI KQKDVPILSI
NRPTFIHDFA ITKRFAIFSE TQLAVSAANV MLGKGMPTVF VPEKIPRIGI ILKYATSDAE
MKWFNVPGFN AMHVFNAWEN GDDEIVLIAT TATSIENLFH KIDMVHFSLE KVRINLRTGH
VFRNILSTRN LELGSINSSY IGKKNRYWVK KFLKWKEFCF GGEPLFVPRN EDHLDAADED
DGFVVTYIHD EIHEESKFLV MDAKSPI
//
