ID   A0A2H5Q4B9_CITUN        Unreviewed;       858 AA.
AC   A0A2H5Q4B9;
DT   28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=Non-specific serine/threonine protein kinase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=CUMW_194420 {ECO:0000313|EMBL:GAY59421.1};
OS   Citrus unshiu (Satsuma mandarin) (Citrus nobilis var. unshiu).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus.
OX   NCBI_TaxID=55188 {ECO:0000313|EMBL:GAY59421.1};
RN   [1] {ECO:0000313|EMBL:GAY59421.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=29259619; DOI=10.3389/fgene.2017.00180;
RA   Shimizu T., Tanizawa Y., Mochizuki T., Nagasaki H., Yoshioka T., Toyoda A.,
RA   Fujiyama A., Kaminuma E., Nakamura Y.;
RT   "Draft sequencing of the heterozygous diploid genome of Satsuma (Citrus
RT   unshiu Marc.) using a hybrid assembly approach.";
RL   Front. Genet. 8:180-180(2017).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAY59421.1}.
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DR   EMBL; BDQV01000210; GAY59421.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2H5Q4B9; -.
DR   STRING; 55188.A0A2H5Q4B9; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.
DR   GO; GO:0004521; F:RNA endonuclease activity; IEA:InterPro.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IEA:InterPro.
DR   GO; GO:0006397; P:mRNA processing; IEA:InterPro.
DR   Gene3D; 1.20.1440.180; KEN domain; 1.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR045133; IRE1/2-like.
DR   InterPro; IPR010513; KEN_dom.
DR   InterPro; IPR038357; KEN_sf.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR008271; Ser/Thr_kinase_AS.
DR   PANTHER; PTHR13954; IRE1-RELATED; 1.
DR   PANTHER; PTHR13954:SF6; NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE; 1.
DR   Pfam; PF00069; Pkinase; 1.
DR   Pfam; PF06479; Ribonuc_2-5A; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   PROSITE; PS51392; KEN; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           27..858
FT                   /note="Non-specific serine/threonine protein kinase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5014139898"
FT   DOMAIN          480..768
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
FT   DOMAIN          771..858
FT                   /note="KEN"
FT                   /evidence="ECO:0000259|PROSITE:PS51392"
FT   REGION          295..320
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        295..310
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   858 AA;  95200 MW;  61CE4EF16B34A381 CRC64;
     MSPLTHRSFR CSLLLVLLLT VVLISGFCNG ESSASASASS LSTSLIRDST ASDRSSGPGR
     SLLSLPDSNG RVSWTFGTGT PIYSSYQAPV QATVDQDNAS ELTNSFFIDC GEDWGLYAHG
     LLGRMKLPQS IDDYVKTAPH ITEEGAVTLG SKTTTVFVLE AKTGRLIRTY GSPHSSSTLQ
     NEEQKSASYK HDKVNNEQLV KSGLTNTAEL QHKEPYLLFI TRTDYTLQSF EPNSDNVSWS
     MTVAEIGYAF LCQDFENPFI GATMNTSYEL GPEIGHDFDL PFACQSKGII QRFRKHNNSD
     SSRRDNHGKP KMLPAPAPDP MAFMQPKADK LSELHHNDGG EGVLTLPPLE TRVSGIVDAY
     DVRTPYKNVL SMLFEQSTAL SLLLLAMTVV GFVVRNSLVA KGQFLLSGHP SLSNSRTAAS
     KRKKVCKLGK NGAVVEKKVE NMSSGNESGF SISKDASDPF LDLNKLVRGG AQGRNVGKLF
     VSNTEIAKGS NGTVVYEGIY EGRPVAVKRL VRALHDVAFK EIQNLIASDQ HPNIVRWYGV
     ENDKDFVYLS LERCTCSLDD LIQTYSDSSC NSVFGEDQAT RAMIEYKLRL DSVKVIIRDL
     SLWKANGHPS PLLLSLMRDL VSGLVHLHEL GIIHRDLKPQ NVLIIKERSL CAKLSDMGIS
     RRLLGDMSSL GHHATGNSGW QAPEQLLHGR QTRAVDLFSL GCVLFFCITG GRHPFGDRLE
     RDINITKNQV DLFLLGCIPE AEDLISRLLN PDPQLRPCAL EVLHHPLFWS SEMRLSFLRD
     TSDRVELEDR ETDSNLLKAL ESSASVSLGA KWDEKIEPIF ITNIGRYRRY KFDSVRDLLR
     VVRNKLNHYR ELPEEIQV
//